Skip to main content
Top
Published in: BMC Infectious Diseases 1/2024

Open Access 01-12-2024 | Yersina Enterocolitica | Case Report

Thyroid abscess associated with thyrotoxicosis caused by Yersinia enterocolitica subsp. palearctica in a patient with follicular adenoma of the thyroid gland

Authors: Takehiro Hashimoto, Takaaki Yahiro, Sonoka Takakura, Sakirul Khan, Kazunori Kimitsuki, Kazufumi Hiramatsu, Akira Nishizono

Published in: BMC Infectious Diseases | Issue 1/2024

Login to get access

Abstract

Background

Yersinia enterocolitica is a gram-negative zoonotic bacterial pathogen that is typically transmitted via the fecal-oral route. The most common clinical manifestation of a Y. enterocolitica infection is self-limited gastroenteritis. Although various extraintestinal manifestations of Y. enterocolitica infection have been reported, there are no reports of thyroid abscesses.

Case presentation

An 89-year-old Japanese man with follicular adenoma of the left thyroid gland was admitted to our hospital with a 2-day history of fever and left neck pain. Laboratory tests revealed low levels of thyroid stimulating hormone and elevated levels of free thyroxine 4. Contrast-enhanced computed tomography showed low-attenuation areas with peripheral enhancement in the left thyroid gland. He was diagnosed with thyroid abscess and thyrotoxicosis, and treatment with intravenous piperacillin-tazobactam was initiated after collecting blood, drainage fluid, and stool samples. The isolated Gram-negative rod bacteria from blood and drainage fluid cultures was confirmed to be Y. enterocolitica. He was diagnosed with thyroid abscess and thyrotoxicosis due to be Y. enterocolitica subsp. palearctica. The piperacillin-tazobactam was replaced with levofloxacin.

Conclusion

We report a novel case of a thyroid abscess associated with thyrotoxicosis caused by Y. enterocolitica subsp. palearctica in a patient with a follicular thyroid adenoma.
Literature
1.
go back to reference Drummond N, Murphy BP, Ringwood T, Prentice MB, Buckley JF, Fanning S. Yersinia enterocolitica: a brief review of the issues relating to the zoonotic pathogen, public health challenges, and the pork production chain. Foodborne Pathog Dis. 2012;9(3):179–89.CrossRefPubMed Drummond N, Murphy BP, Ringwood T, Prentice MB, Buckley JF, Fanning S. Yersinia enterocolitica: a brief review of the issues relating to the zoonotic pathogen, public health challenges, and the pork production chain. Foodborne Pathog Dis. 2012;9(3):179–89.CrossRefPubMed
2.
go back to reference Huovinen E, Sihvonen LM, Virtanen MJ, Haukka K, Siitonen A, Kuusi M. Symptoms and sources of Yersinia enterocolitica-infection: a case-control study. BMC Infect Dis. 2010;10:122.CrossRefPubMedPubMedCentral Huovinen E, Sihvonen LM, Virtanen MJ, Haukka K, Siitonen A, Kuusi M. Symptoms and sources of Yersinia enterocolitica-infection: a case-control study. BMC Infect Dis. 2010;10:122.CrossRefPubMedPubMedCentral
5.
go back to reference Dv K, Gunasekaran K, Mishra AK, Iyyadurai R. Disseminated tuberculosis presenting as cold abscess of the thyroid gland-a case report. Oxf Med Case Rep. 2017;2017:omx049.CrossRef Dv K, Gunasekaran K, Mishra AK, Iyyadurai R. Disseminated tuberculosis presenting as cold abscess of the thyroid gland-a case report. Oxf Med Case Rep. 2017;2017:omx049.CrossRef
6.
go back to reference Takehara T, Tani T, Yajima K, Watanabe M, Otsuka Y, Koh H. First case report of thyroid abscess caused by helicobacter cinaedi presenting with thyroid storm. BMC Infect Dis. 2019;19:166.CrossRefPubMedPubMedCentral Takehara T, Tani T, Yajima K, Watanabe M, Otsuka Y, Koh H. First case report of thyroid abscess caused by helicobacter cinaedi presenting with thyroid storm. BMC Infect Dis. 2019;19:166.CrossRefPubMedPubMedCentral
7.
go back to reference Seyedjavadeyn Z, Miratashi Yazdi SA, Samimiat A, Vahedi M. Thyrotoxicosis as a rare presentation in acute suppurative thyroiditis: a case report. J Med Case Rep. 2023;17:428.CrossRefPubMedPubMedCentral Seyedjavadeyn Z, Miratashi Yazdi SA, Samimiat A, Vahedi M. Thyrotoxicosis as a rare presentation in acute suppurative thyroiditis: a case report. J Med Case Rep. 2023;17:428.CrossRefPubMedPubMedCentral
8.
go back to reference San Martin VT, Kausel AM, Albu JB. Haemophilus influenzae as a rare cause of acute suppurative thyroiditis with thyrotoxicosis and thyroid abscess formation in a patient with pre-existent multinodular goiter. AACE Clin Case Rep. 2017;3:e251–4.CrossRef San Martin VT, Kausel AM, Albu JB. Haemophilus influenzae as a rare cause of acute suppurative thyroiditis with thyrotoxicosis and thyroid abscess formation in a patient with pre-existent multinodular goiter. AACE Clin Case Rep. 2017;3:e251–4.CrossRef
9.
go back to reference McLaughlin SA, Smith SL, Meek SE. Acute suppurative thyroiditis caused by Pasteurella multocida and associated with thyrotoxicosis. Thyroid. 2006;16:307–10.CrossRefPubMed McLaughlin SA, Smith SL, Meek SE. Acute suppurative thyroiditis caused by Pasteurella multocida and associated with thyrotoxicosis. Thyroid. 2006;16:307–10.CrossRefPubMed
10.
go back to reference Thoerner P, Bin Kingombe CI, Bögli-Stuber K, Bissig-Choisat B, Wassenaar TM, Frey J, et al. PCR detection of virulence genes in Yersinia enterocolitica and Yersinia pseudotuberculosis and investigation of virulence gene distribution. Appl Environ Microbiol. 2003;69(3):1810–6.CrossRefPubMedCentral Thoerner P, Bin Kingombe CI, Bögli-Stuber K, Bissig-Choisat B, Wassenaar TM, Frey J, et al. PCR detection of virulence genes in Yersinia enterocolitica and Yersinia pseudotuberculosis and investigation of virulence gene distribution. Appl Environ Microbiol. 2003;69(3):1810–6.CrossRefPubMedCentral
11.
go back to reference Garzetti D, Susen R, Fruth A, Tietze E, Heesemann J, Rakin A. A molecular scheme for Yersinia enterocolitica patho-serotyping derived from genome-wide analysis. Int J Med Microbiol. 2014;304(3–4):275–83.CrossRefPubMed Garzetti D, Susen R, Fruth A, Tietze E, Heesemann J, Rakin A. A molecular scheme for Yersinia enterocolitica patho-serotyping derived from genome-wide analysis. Int J Med Microbiol. 2014;304(3–4):275–83.CrossRefPubMed
12.
go back to reference Fàbrega A, Vila J. Yersinia enterocolitica: pathogenesis, virulence and antimicrobial resistance. Enferm Infecc Microbiol Clin. 2012;30(1):24–32.CrossRefPubMed Fàbrega A, Vila J. Yersinia enterocolitica: pathogenesis, virulence and antimicrobial resistance. Enferm Infecc Microbiol Clin. 2012;30(1):24–32.CrossRefPubMed
13.
go back to reference AlYousef MK, Al-Sayed AA, Al Afif A, Alamoudi U, LeBlanc JM, LeBlanc R. A pain in the neck: Salmonella spp. as an unusual cause of a thyroid abscess. A case report and review of the literature. BMC Infect Dis. 2020;20(1):436.CrossRefPubMedPubMedCentral AlYousef MK, Al-Sayed AA, Al Afif A, Alamoudi U, LeBlanc JM, LeBlanc R. A pain in the neck: Salmonella spp. as an unusual cause of a thyroid abscess. A case report and review of the literature. BMC Infect Dis. 2020;20(1):436.CrossRefPubMedPubMedCentral
14.
go back to reference Falhammar H, Wallin G, Calissendorff J. Acute suppurative thyroiditis with thyroid abscess in adults: clinical presentation, treatment and outcomes. BMC Endocr Disord. 2019;19(1):130.CrossRefPubMedPubMedCentral Falhammar H, Wallin G, Calissendorff J. Acute suppurative thyroiditis with thyroid abscess in adults: clinical presentation, treatment and outcomes. BMC Endocr Disord. 2019;19(1):130.CrossRefPubMedPubMedCentral
15.
go back to reference Ghaemi N, Sayedi J, Bagheri S. Acute suppurative thyroiditis with thyroid abscess: a case report and review of the literature. Iran J Otorhinolaryngol. 2014;26:51–5.PubMedPubMedCentral Ghaemi N, Sayedi J, Bagheri S. Acute suppurative thyroiditis with thyroid abscess: a case report and review of the literature. Iran J Otorhinolaryngol. 2014;26:51–5.PubMedPubMedCentral
16.
go back to reference Lethert K, Bowerman J, Pont A, Earle K, Garcia-Kennedy R. Methicillin-resistant Staphylococcus aureus suppurative thyroiditis with thyrotoxicosis. Am J Med. 2006;119:e1–2.CrossRefPubMed Lethert K, Bowerman J, Pont A, Earle K, Garcia-Kennedy R. Methicillin-resistant Staphylococcus aureus suppurative thyroiditis with thyrotoxicosis. Am J Med. 2006;119:e1–2.CrossRefPubMed
17.
go back to reference Zangiabadian M, Mirsaeidi M, Pooyafar MH, Goudarzi M, Nasiri MJ. Associations of Yersinia Enterocolitica infection with autoimmune thyroid diseases: a systematic review and Meta-analysis. Endocr Metab Immune Disord Drug Targets. 2021;21(4):682–7.CrossRefPubMed Zangiabadian M, Mirsaeidi M, Pooyafar MH, Goudarzi M, Nasiri MJ. Associations of Yersinia Enterocolitica infection with autoimmune thyroid diseases: a systematic review and Meta-analysis. Endocr Metab Immune Disord Drug Targets. 2021;21(4):682–7.CrossRefPubMed
Metadata
Title
Thyroid abscess associated with thyrotoxicosis caused by Yersinia enterocolitica subsp. palearctica in a patient with follicular adenoma of the thyroid gland
Authors
Takehiro Hashimoto
Takaaki Yahiro
Sonoka Takakura
Sakirul Khan
Kazunori Kimitsuki
Kazufumi Hiramatsu
Akira Nishizono
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2024
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-024-08974-1

Other articles of this Issue 1/2024

BMC Infectious Diseases 1/2024 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine