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24-11-2023 | Wound Debridement | Case Based Review

Healing refractory livedoid vasculopathy-related skin ulcers by ozone therapy: a case-based review

Authors: Gulsah Yasa Ozturk, Burhan Fatih Kocyigit

Published in: Rheumatology International | Issue 2/2024

Abstract

Chronic skin wounds represent a prominent etiological factor in the occurrence of non-traumatic foot amputations on a global scale and pose a substantial threat to the patient’s well-being and mortality in the absence of effective treatment strategies. There exists a subset of patients that exhibit an insufficient response to different treatment options, comprising antibiotics, dressings, gauze bandages, debridement, rehabilitation, collagen patch, and vacuum-assisted closure. In this patient group, distinct treatment strategies emerge before surgery and amputation. Ozone therapy is one of them. Ozone exhibits a wide variety of effects such as antimicrobial, anti-inflammatory, antioxidant, and trophic. Its trophic effect is mediated by disinfection, stimulation of granulation tissue, acceleration of the angiogenesis process, and detoxification mechanisms. In this article, we presented the beneficial effect of ozone therapy in a case of chronic skin ulcer associated with livedoid vasculopathy. In this context, we aimed to discuss the role of ozone therapy in the management of chronic skin ulcers. Finally, we focused on ozone therapy as a promising method in inflammatory rheumatic diseases.

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Title: Healing refractory livedoid vasculopathy-related skin ulcers by ozone therapy: a case-based review
Authors: Gulsah Yasa Ozturk
Burhan Fatih Kocyigit
Publication date: 24-11-2023
Publisher: Springer Berlin Heidelberg
Keyword: Wound Debridement
Published in: Rheumatology International / Issue 2/2024
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI: https://doi.org/10.1007/s00296-023-05504-1

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