Skip to main content
Top
Published in: Pediatric Radiology 2/2015

01-02-2015 | Research Forum

What you need to know about statistics Part I: validity of diagnostic and screening tests

Authors: Ronald L. Thomas, Marwan A. Zidan, Thomas L. Slovis

Published in: Pediatric Radiology | Issue 2/2015

Login to get access

Abstract

The intent of this manuscript is to provide guidance and support to clinicians and investigators for reporting the results of screening and diagnostic tests. This article is the first of two parts addressing statistics in imaging research. In this part validity measures are discussed. In part II reliability measures will be discussed. In discussing validity, the following concepts will be introduced: (1) functions of diagnostic tests, (2) statistical characteristics of diagnostic tests and application of validity measures, (3) power and sample size for testing the sensitivity and specificity of the diagnostic test, (4) statistical versus clinical significance and (5) characteristics of a useful diagnostic test.
Literature
1.
go back to reference Wald N, Cuckle H (1989) Reporting the assessment of screening and diagnostic tests. Br J Obstet Gynaecol 4:389–396CrossRef Wald N, Cuckle H (1989) Reporting the assessment of screening and diagnostic tests. Br J Obstet Gynaecol 4:389–396CrossRef
2.
go back to reference Lang TA, Secic M (1997) How to report statistics in medicine. BMJ Publishing Group, Philadelphia Lang TA, Secic M (1997) How to report statistics in medicine. BMJ Publishing Group, Philadelphia
3.
go back to reference Haynes RB (1981) How to read clinical journals: II. To learn about a diagnostic test. Can Med Assoc J 124:703–710 Haynes RB (1981) How to read clinical journals: II. To learn about a diagnostic test. Can Med Assoc J 124:703–710
5.
go back to reference Trochim W, Donnelly JP (2007) The research methods knowledge base. Cengage Learning-Atomic Dog Publishing, Mason Trochim W, Donnelly JP (2007) The research methods knowledge base. Cengage Learning-Atomic Dog Publishing, Mason
6.
go back to reference Li J, Fine J (2004) On sample size for sensitivity and specificity in prospective diagnostic accuracy studies. Stat Med 23:2537–2550PubMedCrossRef Li J, Fine J (2004) On sample size for sensitivity and specificity in prospective diagnostic accuracy studies. Stat Med 23:2537–2550PubMedCrossRef
8.
go back to reference Reid MC, Lachs MS, Feinstein AR (1995) Use of methodological standards in diagnostic test research. JAMA 274:645–651PubMedCrossRef Reid MC, Lachs MS, Feinstein AR (1995) Use of methodological standards in diagnostic test research. JAMA 274:645–651PubMedCrossRef
10.
go back to reference Altman DG (1990) Practical statistics for medical research. Chapman and Hall, London Altman DG (1990) Practical statistics for medical research. Chapman and Hall, London
11.
go back to reference Sardanelli F, Giovanni DL (2009) Biostatistics for radiologists: planning, performing, and writing a radiologic study. Springer, MilanCrossRef Sardanelli F, Giovanni DL (2009) Biostatistics for radiologists: planning, performing, and writing a radiologic study. Springer, MilanCrossRef
Metadata
Title
What you need to know about statistics Part I: validity of diagnostic and screening tests
Authors
Ronald L. Thomas
Marwan A. Zidan
Thomas L. Slovis
Publication date
01-02-2015
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Radiology / Issue 2/2015
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-014-2882-7

Other articles of this Issue 2/2015

Pediatric Radiology 2/2015 Go to the issue