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Open Access 01-02-2011 | Poster presentation

What happens to all that propofol during prolonged sedation?

Authors: N Cowley, TH Clutton-Brock

Published in: Critical Care | Special Issue 1/2011

Excerpt

There are few published data on the pharmacokinetics of propofol infusion for prolonged periods in critical care. Propofol is frequently infused for days or weeks in critically ill patients with organ dysfunction. We aimed to determine whether propofol concentrations in critically ill patients are predictable during constant rate infusion, and whether significant organ failure might lead to accumulation when compared with conventional pharmacokinetic models. …

Cavaliere F: Br J Anaesth. 2005, 94: 453-458.CrossRefPubMed

McMurray TJ, et al.: Anaesthesia. 2004, 59: 636-641.CrossRefPubMed

Title: What happens to all that propofol during prolonged sedation?
Authors: N Cowley
TH Clutton-Brock
Publication date: 01-02-2011
Publisher: BioMed Central
Published in: Critical Care / Issue Special Issue 1/2011
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/cc9778

Keynote webinar | Spotlight on medication adherence

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What happens to all that propofol during prolonged sedation?

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

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