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Published in: BMC Nephrology 1/2012

Open Access 01-12-2012 | Research article

What do we know about chronic kidney disease in India: first report of the Indian CKD registry

Authors: Mohan M Rajapurkar, George T John, Ashok L Kirpalani, Georgi Abraham, Sanjay K Agarwal, Alan F Almeida, Sishir Gang, Amit Gupta, Gopesh Modi, Dilip Pahari, Ramdas Pisharody, Jai Prakash, Anuradha Raman, Devinder S Rana, Raj K Sharma, RN Sahoo, Vinay Sakhuja, Ravi Raju Tatapudi, Vivekanand Jha

Published in: BMC Nephrology | Issue 1/2012

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Abstract

Background

There are no national data on the magnitude and pattern of chronic kidney disease (CKD) in India. The Indian CKD Registry documents the demographics, etiological spectrum, practice patterns, variations and special characteristics.

Methods

Data was collected for this cross-sectional study in a standardized format according to predetermined criteria. Of the 52,273 adult patients, 35.5%, 27.9%, 25.6% and 11% patients came from South, North, West and East zones respectively.

Results

The mean age was 50.1 ± 14.6 years, with M:F ratio of 70:30. Patients from North Zone were younger and those from the East Zone older. Diabetic nephropathy was the commonest cause (31%), followed by CKD of undetermined etiology (16%), chronic glomerulonephritis (14%) and hypertensive nephrosclerosis (13%). About 48% cases presented in Stage V; they were younger than those in Stages III-IV. Diabetic nephropathy patients were older, more likely to present in earlier stages of CKD and had a higher frequency of males; whereas those with CKD of unexplained etiology were younger, had more females and more frequently presented in Stage V. Patients in lower income groups had more advanced CKD at presentation. Patients presenting to public sector hospitals were poorer, younger, and more frequently had CKD of unknown etiology.

Conclusions

This report confirms the emergence of diabetic nephropathy as the pre-eminent cause in India. Patients with CKD of unknown etiology are younger, poorer and more likely to present with advanced CKD. There were some geographic variations.
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Metadata
Title
What do we know about chronic kidney disease in India: first report of the Indian CKD registry
Authors
Mohan M Rajapurkar
George T John
Ashok L Kirpalani
Georgi Abraham
Sanjay K Agarwal
Alan F Almeida
Sishir Gang
Amit Gupta
Gopesh Modi
Dilip Pahari
Ramdas Pisharody
Jai Prakash
Anuradha Raman
Devinder S Rana
Raj K Sharma
RN Sahoo
Vinay Sakhuja
Ravi Raju Tatapudi
Vivekanand Jha
Publication date
01-12-2012
Publisher
BioMed Central
Published in
BMC Nephrology / Issue 1/2012
Electronic ISSN: 1471-2369
DOI
https://doi.org/10.1186/1471-2369-13-10

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