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Health Services and Outcomes Research Methodology

Published in:

01-07-2011

Well-being and obesity of rheumatoid arthritis patients

Authors: Nicholas T. Longford, Catia Nicodemo, Montserrat Núñez, Esther Núñez

Published in: Health Services and Outcomes Research Methodology | Issue 1-2/2011

Abstract

We apply the potential outcomes framework in the analysis of an observational study of rheumatoid arthritis patients, in which we compare the mean functional-health and well-being scores (SF–36) of patients who are overweight and who are not. We combine propensity score matching with multiple imputation for nonresponse. We assess the sensitivity of the conclusions with respect to the details of the propensity model and the definition of being overweight.

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Angst, F., Aeschlimann, A., Stucki, G.: Smallest detectable and minimal clinically important differences of rehabilitation intervention with their implications for required sample sizes using WOMAC and SF-36 quality of life measurement instruments in patients with osteoarthritis of the lower extremities. Arthritis Rheum. 4, 384–391 (2001)CrossRef

Hays, R.D., Morales, L.S.: The RAND-36 measure of health-related quality of life. Ann. Med. 33, 350–357 (2001)PubMedCrossRef

Holland, P.B.: Statistics and causal inference. J. Am. Stat. Assoc. 81, 945–970 (1986)CrossRef

Kurth, T., Walker, A.M., Glynn, R.J., Chan, A.K., Gaziano, J.M., Berger, K., Robins, J.M.: Results of multivariable logistic regression, propensity matching, propensity adjustment and propensity-based weighting under conditions of nonuniform effect. Am. J. Epidemiol. 163, 262–270 (2006)PubMedCrossRef

Little, R.J.A., Rubin, D.B.: Statistical Analysis with Missing Data, 2nd edn. Wiley, New York (2002)

Longford, N.T.: Missing Data and Small-Area Estimation. Modern Analytical Equipment for the Survey Statistician. Springer-Verlag, New York (2005)

Longford, N.T.: Studying Human Populations. An Advanced Course in Statistics. Springer-Verlag, New York (2008)CrossRef

Núñez, M., Núñez, E., Sanchez, A., Luis de Val, J., Bonet, M., Roig, D., Muñoz, D., and the ARQUALIS Study Group: Patients’ perceptions of health-related quality of life in rheumatoid arthritis. Clin. Rheumatol. 28, 1157–1165 (2009)PubMedCrossRef

R Development Core Team: R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing, Vienna, Austria (2009)

Rosenbaum, P.R.: Observational Studies, 2nd edn. Springer-Verlag, New York (2002)

Rosenbaum, P.R., Rubin, D.B.: The central role of the propensity score in observational studies for causal effects. Biometrika 70, 41–55 (1983)CrossRef

Rubin, D.B.: Multiple Imputation for Nonresponse in Surveys, 2nd edn. Wiley, New York (2002)

Rubin, D.B.: Causal inference using potential outcomes: design, modeling, decisions. 2004 Fisher Lecture. J. Am. Stat. Assoc. 100, 322–331 (2005)CrossRef

Rubin, D.B.: Matched Sampling for Causal Effects. Wiley, New York (2006)

Rubin, D.B., Thomas, N.: Characterizing the effect of matching using linear propensity score methods with normal distributions. Biometrika 79, 797–809 (1992)CrossRef

Rubin, D.B., Thomas, N.: Matching using estimated propensity scores: relating theory to practice. Biometrics 52, 249–264 (1996)PubMedCrossRef

van Buuren, S., Boshuizen, H.C., Knook, D.L.: Multiple imputation of missing blood pressure covariates in survival analysis. Stat. Med. 18, 681–694 (1999)PubMedCrossRef

van Buuren, S., Groothuis-Oudshoorn, K.: Multiple imputation by chained equations in R . J. Stat. Softw. 37, forthcoming (2011)

Walters, S.J., Brazier, J.E.: What is the relationship between the minimally important difference and health state utility values? The case of the SF-6D. Health Qual. Life Outcomes 1, 4 (2003)PubMedCrossRef

Title: Well-being and obesity of rheumatoid arthritis patients
Authors: Nicholas T. Longford
Catia Nicodemo
Montserrat Núñez
Esther Núñez
Publication date: 01-07-2011
Publisher: Springer US
Published in: Health Services and Outcomes Research Methodology / Issue 1-2/2011
Print ISSN: 1387-3741
Electronic ISSN: 1572-9400
DOI: https://doi.org/10.1007/s10742-011-0070-x

At a glance: The STEP trials

Springer Medicine

Well-being and obesity of rheumatoid arthritis patients

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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