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01-02-2020 | Book Review

Was Hawan Designed to Fight Anxiety-Scientific Evidences?

Authors: R. K. Romana, A. Sharma, V. Gupta, R. Kaur, S. Kumar, P. Bansal

Published in: Journal of Religion and Health | Issue 1/2020

Abstract

Anxiety is a psychiatric disorder with unknown neurobiology; however, neurotransmitters like gamma-amino butyric acid, norepinephrine and serotonin (5-HT) play crucial roles in mediating anxiety. Present drug modules pose dependence risk to the patient; hence, there is a great need to develop complementary therapies to fight this disorder. Aromatherapy has also been employed in ancient times for a number of mental disorders. Mahamrituanjay Mantra, Om triambkum yajamahe, sughandhim puushtivardhanam, urvarukmev vandhanaat, mrityu mokshay mamritaat!!!!, the part of veda enlightens that aroma gives rise to good health (sughandhim puushtivardhanam). Hawan is a religious practice recommended for mental peace. Hawan is a process in which special herbs are offered in the fire of medicinal woods ignited in a specially designed fire pit. Analysis of literature demonstrates that the components of Hawan are having a number of volatile oils that are specifically useful for prevention and treatment of anxiety through some mechanism of action. Due to high temperature of fire, the vapors of these oils from herbs enter into the central nervous system through nasal route. As per modern science and ancient texts on medicine, nasal drug delivery systems are the best for the diseases related to brain and head. The routine of performing Hawan might keep the threshold value of the therapeutic components in the body and help in preventing anxiety. In the present manuscript, authors highlight and integrate the modern and ancient concepts for treatment and prevention of anxiety through scientific evidences.

Ahmad, A. S., Ansari, M. A., Ahmad, M., Saleem, S., Yousuf, S., Hoda, M. N., et al. (2005). Neuroprotection by crocetin in a hemi-parkinsonian rat model. Pharmacology, Biochemistry and Behavior,81, 805–813.PubMed

Akhondzabeh, S., Fallah-Pour, H., Afkham, K., Jamshidi, A. H., & KhalighiCigaroudi, F. (2004). Comparison of Crocus sativus L., and imipramine in the treatment of mild to moderate depression: A pilot double-blind, randomized trial. Complementary and Alternative Medicine,4, 12–16.

Akhondzadeh, S., Tahmacebi-Pour, N., Noorbala, A. A., Amini, H., Fallah-Pour, H., Jamshidi, A. H., et al. (2005). Crocus sativus L. in the treatment of mild to moderate depression: A double-blind, randomized and placebo-controlled trial. Phytotherapy Research,19(2), 148–151.PubMed

Al-Reza, S. M., Bajpai, V. K., & Kang, S. C. (2009). Antioxidant and antilisterial effect of seed essential oil and organic extracts from Zizyphus jujuba. Food and Chemical Toxicology,47, 2374–2380.PubMed

Andreatini, R., Sartori, V. A., Seabra, M. L., & Leite, J. R. (2002). Effect of valepotriates (valerian extract) in generalized anxiety disorder: a randomized placebo-controlled pilot study. Phytotherapy Research,16(7), 650–654.PubMed

Arikian, S. R., & Gorman, J. M. (2001). A review of the diagnosis, pharmacologic treatment and economic aspects of anxiety disorders. Primary Care Companion Journal of Clinical Psychiatry,3, 110–117.

Arora, R. B., Singh, K. P., Das, P. K., & Mistry, P. N. (1958). Prolonged hypotensive effect of the essential oil of Nardostachys jatamansi. Archives Internationales de Pharmacodynamie et de Therapie,113, 367–376.PubMed

Ballard, C. G., Gauthier, S., Cummings, J. L., Brodaty, H., Grossberg, G. T., Robert, P., et al. (2009). Management of agitation and aggression associated with Alzheimer disease. Nature Reviews Neurology,5(5), 245–255.PubMed

Bansal, P., Kaur, R., Gupta, V., Kumar, S., & Kaur, R. P. (2015). Is there any scientific basis of Hawan to be used in epilepsy—Prevention/cure? Journal of Epilepsy Research,2, 33–45.

Bansal, P., Sannd, R., Srikanth, N., & Lavekar, G. S. (2009). Effect of a traditionally designed nutraceutical on the stress induced immunoglobulin changes at Antarctica. African Journal of Biochemistry Research,3, 1084–1088.

Benke, D., Barberis, A., Kopp, S., Altmann, K. H., Schubiger, M., Vogt, K. E., et al. (2009). GABAA receptors as in vivo substrate for the anxiolytic action of valerenic acid, a major constituent of valerian root extracts. Neuropharmacology,56(1), 174–181.PubMed

Bhogwat, V., Chowta, M. N., Shoeb, A., Maskeri, R., Venkatesh, V., & Rai, A. (2013). Evaluation of anxiolytic activity of vanillin in wistar albino rats. International Journal of Nutrition, Pharmacology, Neurological Diseases,3, 96–101.

Bissett, N. G. (1994). Herbal drugs and phytopharmaceuticals. Stuttgart. Med Pharm (pp. 566–567). Boca Raton: CRC Press.

Blennow, K., De Leon, M. J., & Zetterberg, H. (2006). Alzheimer’s disease. Lancet,368, 387–403.PubMed

Borhade, P., Tankar, A., Joshi, S., & Khandelwal, K. (2012). Pharmacological Review on Ficus racemosa Linn. IJPRBS,1(6), 51–66.

Bouayed, J. (2010). Polyphenols: A potential new strategy for the prevention and treatment of anxiety and depression. Current Nutrition and Food Science,6, 13–18.

Bouayed, J., Rammal, H., & Soulimani, R. (2009). Oxidative stress and anxiety: relationship and cellular pathways. Oxidative Medicine and Cellular Longevity,2, 63–67.PubMedPubMedCentral

Brad, K. T., & Verduin, M. L. (2005). Pharmacotherapy of comorbid mood, anxiety, and substance use disorders. Substance Use Misuse,40, 2021–2041.

Bradley, P. R. (1992). British herbal compendium (Vol. 1). Bournemouth: British Herbal Medicine Association.

Brown, R. P., & Gerbarg, P. L. (2001). Herbs and nutrients in the treatment of depression, anxiety, insomnia, migraine, and obesity. Journal of Psychiatric Practice,7, 75–91.PubMed

Chahar, M. K., Kumar, S. D. S., Lokesh, T., & Manohara, K. P. (2012). In-vivo antioxidant and immunomodulatory activity of mesuol isolated from Mesua ferrea L. seed oil. International Immunopharmacology,13(4), 386–391.PubMed

Chen, W. W., He, R. R., Li, Y. F., Li, S. B., & Kurihara, H. (2011). Pharmacological studies on the anxiolytic effect of standardized Schisandra lignans extract on restraint-stressed mice. Phytomedicine,18, 1144–1147.PubMed

Chopra, R. N. (1982). Chopra’s indigenous drugs of India (2nd ed.). Calcutta: Academic Publishers.

Cotran, R. S., Kumar, V., & Collins, T. (2000). Robbins pathologic basis of disease (6th ed.). Pennsylvania: Saunders.

Devane, C. L., Chiao, E., Franklin, M., & Kruep, E. J. (2005). Anxiety disorders in the 21st century: Status, challenges, opportunities, and comorbidity with depression. The American Journal of Managed Care,11(12), 344–353.

El Tinay, A. H., Khattab, A. H., & Khidir, M. O. (1976). Protein and oil compositions of sesame seed. Journal of the American Oil Chemists Society,53, 648–653.

El-Sayed, M. U., & Labban, L. (2013). Effect of Zizyphus jujuba on serum lipid profile and some anthropometric measurements. Advancement in Medicinal Plant Research,1(3), 49–55.

Frison, N. S., & Sporns, P. (2010). Identification and quantification of flavonol glycosides in alm5214-41ond seed coats by using MALDI-TOF.MS. Journal of Agricultural and Food Chemistry,50, 2782–2787.

Garabadu, D., Shah, A., Ahmad, A., Joshi, V. B., Saxena, B., Palit, G., et al. (2011). Eugenol as an anti-stress agent: Modulation of hypothalamic-pituitary-adrenal axis and brain monoaminergic systems in a rat model of stress. Stress,14(2), 145–155.PubMed

García-Gutiérrez, M. S., García-Bueno, B., Zoppi, S., Leza, J. C., & Manzanares, J. (2012). Chronic blockade of cannabinoid CB2 receptors induces anxiolytic-like actions associated with alterations in GABA(A) receptors. British Journal of Pharmacology,165(4), 951–964.PubMedPubMedCentral

WHO Monographs on Selected Medicinal Plants-1. Geneva, 1999.

Georgiadou, G., Tarantilis, P. A., & Pitsikas, N. (2012). Effects of the active constituents of Crocus sativus L., crocins, in an animal model of obsessive-compulsive disorder. Neuroscience Letters,528, 27–30.PubMed

Ghadrdoost, B., Vafaei, A. A., Rashidy-Pour, A., Hajisoltani, R., Bandegi, A. R., & Motamedi, F. (2011). Protective effects of saffron extract and its active constituent crocin against oxidative stress and spatial learning and memory deficits induced by chronic stress in rats. European Journal of Pharmacology,667(1), 222–229.PubMed

Grieve, M. (1971). A modern herbal (Ist ed.). New York: Dover Publications.

Guedes, D. N., Silva, D. F., Barbosa-Filho, J. M., & Medeiros, I. A. (2002). Muscarinic agonist properties involved in the hypotensive and vasorelaxant responses of rotundifolone in rats. Planta Medica,68(8), 700–704.PubMed

Hosseinzadeh, H., & Noraei, N. B. (2009). Anxiolytic and hypnotic effect of Crocus sativus aqueous extract and its constituents, crocin and safranal in mice. Phytotherapy Research,23, 768–774.PubMed

Houghton, P. J. (1999). The scientific basis for the reputed activity of Valerian. Journal of Pharmacy and Pharmacology,51, 505–511.PubMed

Hsieh, P. F., Hou, C. W., Yao, P. W., Wu, S. P., Peng, Y. F., Shen, M. L., et al. (2011). Sesamin ameliorates oxidative stress and mortality in kainic acid induced status epilepticus by inhibition of MAPK and COX-2 activation. Journal of Neuroinflammation,8, 57–66.PubMedPubMedCentral

Huang, X., Liu, T., Gu, J., Luo, X., & Cao, Y. (2001). 3D-QSAR model of flavonoids binding at benzodiazepine site of GABA A receptors. Journal of Medicinal Chemistry,44, 1883–1884.PubMed

Huang, P. W., Tsuen, H. M., Shung, L. Y., Chin, L. Y., & Jen, L. (2000). Anxiolytic effect of seed of Ziziphus jujuba in mouse models of anxiety. Journal of Ethnopharmacology,72(3), 435–441.

Jain, S., & Tandon, P. N. (2004). Ayurvedic medicine and Indian literature on epilepsy. Neurology Asia,9, 57–58.

Jirovetz, L., & Buchbauer, G. (2006). Chemical composition and antioxidant properties of clove leaf essential oils. Journal of Agricultural and Food Chemistry,54, 6303–6307.PubMed

Joshi, R. R. (2009). The integrated science of yagna. Mathrua: Yug Nirman Yojna Press.

Kalyanraman, S. (2004). Mleccha: Indus script and sarasvati hieroglyphs (Ist ed.). Bangalore: Baba Saheb (Umakanta Keshava) Apte Smarak Samiti.

Khom, S., Baburin, I., Timin, E., Hohaus, A., Trauner, G., Kopp, B., et al. (2007). Valerenic acid potentiates and inhibits GABAA receptors: Molecular mechanism and subunit specificity. Neuropharmacology,53(1), 178–187.PubMed

Khom, S., Strommeier, B., Ramharter, J., Schwarz, T., Schwarzer, C., Erker, T., et al. (2010). Valerenic acid derivatives as novel subunit-selective ligands—In vitro and in vivo characterization. British Journal of Pharmacology,161(1), 65–78.PubMedPubMedCentral

Kumari, R., Kaundal, M., Ahmad, Z., & Ashwalayan, V. D. (2011). Herbal and dietary supplements in treatment of schizophrenia. An Approach to Improve Therapeutics,10(1), 217–224.

Leiter, E., Hitchcock, G., Godwin, S., Johnson, M., Sedgwick, W., & Jones, W. (2001). Evaluation of the anxiolytic properties of myristicin, a component of nutmeg, in the male sprague-dawley rat. AANA Journal,79, 109–114.

Leiter, E., Hitchcock, G., Godwin, S., Johnson, M., Sedgwick, W., Jones, W., et al. (2011). Anxiolytic effects of myristicin, a major compound found in nutmeg, and its potential interaction with the gamma-aminobutyric acid (GABA(A)) receptor in male Sprague-Dawley rats. AANA Journal,79(2), 109–114.PubMed

Lepine, J. P. (2002). The epidemiology of anxiety disorders: Prevalence and social costs. Journal of Clinical Psychiatry,63(14), 4–8.PubMed

Makhija, I. K., Sharma, I. P., & Khamar, D. (2010). Phytochemistry and Pharmacological properties of Ficus religiosa: An overview. Annals of Biological Research,1(4), 171–180.

Medina, J. H., Viola, H., Wolfman, C., Marder, M., Wasowski, C., Clavo, D., et al. (1997). Neuroactive flavonoids: New ligands for the benzodiazepine receptors. Phytomedicine,5, 235–243.

Moazzami, A. A., & Kamal-Eldin, A. (2006). Sesame seed is a rich source of dietary lignans. Journal of the American Oil Chemists Society,83, 719–723.

Murphy, K., Kubin, Z. J., Shepherd, J. N., & Ettinger, R. H. (2010). Valeriana officinalis root extracts have potent anxiolytic effects in laboratory rats. Phytomedicine,17, 674–678.PubMed

Nagai, M., Wada, M., Usui, N., Tanaka, A., & Hasebe, Y. (2000). Pleasant odors attenuate the blood pressure increase during rhythmic handgrip in humans. Neuroscience Letters,289(3), 227–229.PubMed

Naska, S., Mazumder, U. K., Pramanik, G., Bala, A., Haldar, P. K., Islam, A., et al. (2011). Comparative in vitro antioxidant activity of different parts of Cocos nucifera (linn) on reactive oxygen and nitrogen species. International Journal of Pharmacy and Pharmaceutical Sciences,3, 104–107.

Neelakanth, M. J., Bhat, M. R., Taranalli, A. D., & Veeresh, B. (2012). Effect of Buchanania lanzan seeds on learning and memory in normal and memory deficit rats. Journal of Researchers in Pharmabiomedica,22(1), 33–38.

Neha, S., Purohit, V. K., Andola, H., Rana, M., Chauhan, R. S., & Nautiya, A. R. (2012). Biological activities of Valeriana wallichi DC medicinal plants. International Journal of Phytomedicines and Related Industries,4(3), 115–120.

Nierenberg, A. A. (2001). Current perspectives on the diagnosis and treatment of major depressive disorder. The American Journal of Managed Care,7, 353–366.

Nigam, R., & Hashimi, N. H. (2002). Has sea level fluctuations modulated human settlements in gulf of Khambat (Cambay). Journal of Geological Society of India,59, 583–584.

Noorbala, A., Akhondzadeh, S., Tahmacebi-Pour, N., & Jamshidi, A. (2005). Hydro-alcoholic extract of Crocus sativus L. versus fluoxetine in the treatment of mild to moderate depression: A double-blind, randomized pilot trial. Journal of Ethnopharmacology,97, 281–284.PubMed

Ortiz, J. G., Nieves-Natal, J., & Chavez, P. (1999). Effects of Valeriana officinalis extracts on [3H]flunitrazepam binding, synaptosomal [3H]GABA uptake, and hippocampal [3H]GABA release. Neurochemical Research,24, 1373–1378.PubMed

Paladini, A. C., Marder, M., Viola, H., Wolfman, C., Wasowski, C., & Medina, J. H. (1999). Flavonoids and the central nervous system: from forgotten factors to potent anxiolytic compounds. Journal of Pharmacy and Pharmacology,51(5), 519–526.PubMed

Papandreou, M. A., Kanakis, C. D., Polissiou, M. G., Efthimiopoulos, S., Cordopatis, P., Margariti, M., et al. (2006). Inhibitory activity of amyloid- aggregation and antioxidant properties of Crocus sativus extract and its crocins constituents. Journal of Agricultural and Food Chemistry,54, 8762–8768.PubMed

Pathirana, W., Abhayawardhana, P., Kariyawasam, H., & Ratnasooriya, W. D. (2009). Transcranial route of brain targeted delivery of methadone in oil. Indian Journal of Pharmaceutical Sciences,71(3), 264–269.PubMedPubMedCentral

Pinelo, M., Rubilar, M., Sineiro, J., & Nunez, M. J. (2004). Extraction of antioxidant phenolics from almond hulls (Prunus amygdlaus) and pine sawdust (Pinus pinaster). Food Chemistry,85, 267–273.

Pitsikas, N., Boultadakis, A., Georgiadou, G., Tarantilis, P. A., & Sakellaridis, N. (2008). Effects of the active constituents of Crocus sativus L. crocins, in an animal model of anxiety. Phytomedicine,15, 1135–1139.PubMed

Pitsikas, N., & Sakellaridis, N. (2006). Crocus sativus L. extracts antagonize memory impairments in different behavioural tasks in the rat. Behavioural Brain Research,173, 112–115.PubMed

Pitsikas, N., Zisopoulou, S., Tarantilis, P. A., Kanakis, C. D., Polissiou, M. G., & Sakellaridis, N. (2007). Effects of the active constituents of Crocus sativus L. crocins on recognition and spatial rats’ memory. Behavioural Brain Research,183, 141–146.PubMed

Prasad, D. K., & Sriharsha, S. N. (2015). Evaluation of anxiolytic activity of leaf extracts of Nelumbo nucifera in laboratory rodents. International Journal of Pharmacy and Biological Sciences,5, 24–30.

Radhakrishna, A., Kumar, H., & Chamundeeswari, D. (2011). Evaluation of antianxiety activity of Ricinus communis. Pharmanest,2, 362–368.

Rahman, H., Eswaraiah, M. C., Ramesh, S., & Rao, B. M. (2013). Study of anxiolytic activity of some essential oils used by inhalational exposure in Mice. Scholars Journal of Applied Medical Sciences,1(1), 1–4.

Rao, V. S., Rao, A., & Karanth, K. S. (2005). Anticonvulsant and neurotoxicity profile of Nardostahys jatamansi in rats. Journal of Ethnopharmacology,102, 351–356.PubMed

Reddy, P. M., Gobinath, M., Rao, K. M., Venugopalaiah, P., & Reena, N. (2011). A review on importance of herbal drugs in cosmetics. International Journal of Advances in Pharmacy and Nanotechnology,1(3), 121–139.

Reshma, M. V., Balachandran, C., Arumughan, C., Sunderasan, A., Sukumaran, D., Thomas, S., et al. (2010). Extraction, separation and characterisation of sesame oil lignan for nutraceutical applications. Food Chemistry,120, 1041–1046.

Saki, K., Bahmani, M., & Rafieian-Kopaei, M. (2014). Identification of medicinal plants effective in infectious diseases in Urmia, northwest of Iran. Asian Pacific Journal of Tropical Biomedicine,7(1), 34–42.

Sangalli, B. C., & Chiang, W. (2000). Toxicology of nutmeg abuse. Journal of Toxicology, Clinical Toxicology,38, 671–678.PubMed

Sarris, J., McIntyre, E., & Camfield, D. A. (2013). Plant-based medicines for anxiety disorders, Part 1: A review of preclinical studies. CNS Drugs,27(3), 207–219.PubMed

Scorer, C. A. (2001). Preclinical and clinical challenges in the development of disease-modifying therapies for Alzheimer’s disease. Drug Discover Today,6(23), 1207–1219.

Sharma, S., Sharma, J., & Kaur, G. (2011). Therapeutic uses of Elettaria cardomum. International Journal of Drug Formulation and Research,2(6), 102–108.

Singh, P. N., & Singh, S. B. (1980). A new saponin from mature tubes of Cyperus rotundus. Phytochemistry,19, 2056–2057.

Singh, S. B., & Singh, P. N. (1986). A new flavanol glycoside from mature leaves of Cyperus rotundus. Journal of the Indian Chemical Society,63, 450–455.

Sonavane, G. S., Palekar, R. C., Kasture, V. S., & Kasture, S. B. (2002). Anticonvulsant and behavioral actions of Myristica fragrans seeds. Indian Journal of Pharmacology,34, 332–338.

Subashini, R., Gnanapragasam, A., Senthilkumar, S., Yogeeta, S., & Devaki, T. (2007a). Standardization and in vitro antioxidant activity of jatamansi rhizome. Journal of Health Science,53, 67–72.

Subashini, R., Prashanth, D., Salma, K., Sreeja, S. L., Pratiti, D., Padmaja, R., et al. (2007b). Screening of selected Indian medicinal plants for acetylcholinesterase inhibitory activity. Journal of Ethnopharmacology,109, 359–363.

Sugawara, Y., Hara, C., Aoki, T., Sugimoto, N., & Masujima, T. (2000). Odor distinctiveness between enantiomers of linalool: Difference in perception and responses elicited by sensory test and forehead surface potential wave measurement. Chemical Senses,25(1), 77–84.PubMed

Sugiura, M., Shoyama, Y., Saito, H., & Nishiyama, N. (1995). Crocin improves the ethanol-induced impairment of learning behaviors of mice in passive avoidance tasks. Proceedings of Japanese Academy,71, 319–324.

Sushma, N., Smitha, P. V., Gopal, Y. V., Vinay, R., Reddy, N. S., Mohan, C. M., et al. (2013). Antidiabetic, antihyperlipidemic and antioxidant activities of buchanania lanzan spreng methanol leaf extract in streptozotocin-induced types I and II diabetic rats. Tropical Journal of Pharmaceutical Research,12(2), 221–226.

Takeda, T., Tsuji, M., & Matsumiya, T. (1998). Changes in head-dipping behavior in the hole-board test reflect the anxiogenic and/or anxiolytic state in mice. European Journal of Pharmacology,350, 21–29.PubMed

Takemoto, H., Yagura, T., & Ito, M. (2009). Evaluation of volatile components from spikenard: Valerena diene is a highly active sedative compound. Journal of Natural Medicines,63, 380–385.PubMed

Tewary, R., & Mishra, J. K. (1997). Hawan. An effective method to reduce fungal load at small work places. Aerobiologia,13, 135–138.

Trauner, G., Khom, S., Baburin, I., Benedek, B., Hering, S., & Kopp, B. (2007). Modulation of GABAA receptors by valerian extracts is related to the content of valerenic acid. Planta Medica,74, 19–24.PubMed

Trauner, G., Khom, S., Baburin, I., Benedek, B., Hering, S., & Kopp, B. (2008). Modulation of GABAA receptors by valerian extracts is related to the content of valerenic acid. Planta Medica,74(1), 19–24.PubMed

Tripathi, K. D. (2010). Essentials of medical pharmacology (Ist ed.). New Delhi: JP Brothers.

Turker, S., Onur, E., & Ozer, Y. (2004). Nasal route and drug delivery systems. Pharmacy World & Science,26, 137–142.

Veerapur, V. P., Prabhakar, K. R., Parihar, V. K., Kandadi, M. R., & Ramakrishnas, Mishra B. (2007). Ficus racemosa stem bark extract a potent antioxidant and a probable natural radioprotector. Evidence-Based Complementary and Alternative Medicine,3, 205–208.

Zhang, Y., Shoyama, Y., Sugiura, M., & Saito, H. (1994). Effects of Crocus sativus L. on the ethanol-induced impairment of passive avoidance performance in mice. Biological and Pharmaceutical Bulletin,17, 217–221.PubMed

Title: Was Hawan Designed to Fight Anxiety-Scientific Evidences?
Authors: R. K. Romana
A. Sharma
V. Gupta
R. Kaur
S. Kumar
P. Bansal
Publication date: 01-02-2020
Publisher: Springer US
Published in: Journal of Religion and Health / Issue 1/2020
Print ISSN: 0022-4197
Electronic ISSN: 1573-6571
DOI: https://doi.org/10.1007/s10943-016-0345-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Was Hawan Designed to Fight Anxiety-Scientific Evidences?

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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