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Open Access 01-12-2024 | Vulgar Psoriasis | Original Paper

Ocular complications in adults with psoriasis: a cross-sectional study in a referral center in Brazil

Authors: Ricardo Danilo Chagas Oliveira, Adriano Cypriano Faneli, Dillan Cunha Amaral, Julia Motta Chagas, Jaime Guedes, Ivonise Follador, Maria de Fatima Santos Paim de Oliveira, Bruno F. Fernandes, Luis Claudio Lemos Correia

Published in: International Ophthalmology | Issue 1/2024

Abstract

Purpose

There is limited literature on the ocular manifestations in patients with psoriasis. Therefore, this study aimed to identify the prevalence of and factors associated with ocular manifestations in adults with psoriasis.

Methods

This cross-sectional study included Brazilian adults with psoriasis. The dermatological evaluation included diagnosis, clinical form, Psoriasis Area and Severity Index (PASI) measurement, and location of the lesions. Patients underwent a full ophthalmological examination, including the Schirmer I test, Rose Bengala staining, and tear breakup time tests. The results were analyzed using chi-square and Pearson’s linear correlation tests.

Results

Of the 130 patients assessed, 118 (90.8%) exhibited ocular abnormalities, with meibomian gland dysfunction (MGD) being the most prevalent (59.2%), followed by dry eye disease (DED) (56.2%). A significant correlation was observed between MGD and PASI (p = 0.05), and between MGD and certain treatment modalities. DED was significantly associated with PASI (p < 0.05). Concurrent use of acitretin was identified as an independent predictor of MGD (odds ratio [OR] = 3.5, p < 0.05), whereas PASI was a protective factor against DED (OR = 0.39, p < 0.01).

Conclusion

Given the high prevalence of eye disease among individuals with psoriasis, routine ophthalmological assessments are recommended to prevent possible ocular complications.

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Title: Ocular complications in adults with psoriasis: a cross-sectional study in a referral center in Brazil
Authors: Ricardo Danilo Chagas Oliveira
Adriano Cypriano Faneli
Dillan Cunha Amaral
Julia Motta Chagas
Jaime Guedes
Ivonise Follador
Maria de Fatima Santos Paim de Oliveira
Bruno F. Fernandes
Luis Claudio Lemos Correia
Publication date: 01-12-2024
Publisher: Springer Netherlands
Keywords: Vulgar Psoriasis
Xerophthalmia
Uveitis
Published in: International Ophthalmology / Issue 1/2024
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-024-03147-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Ocular complications in adults with psoriasis: a cross-sectional study in a referral center in Brazil

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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