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01-01-2024 | Vulgar Psoriasis | ORIGINAL PAPER

Causal effect of educational attainment on psoriasis risk mediated by obesity-related traits: Mendelian randomization study

Authors: Qianqian Dai, Yanfeng Zhang, Qian Liu, Chijin Zhang

Published in: Archives of Dermatological Research | Issue 1/2024

Excerpt

It is widely believed that socioeconomic deprivation may contribute to an elevated susceptibility to psoriasis [1], there are two important considerations that warrant attention. One is that the ability to make causal inferences from observational associations may be limited, and the other is that it remains unclear whether and to what extent the identified risk factors explain the overall effect of socioeconomic deprivation on the occurrence of psoriasis. …

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Mahé E, Beauchet A, Reguiai Z, Maccari F, Ruer-Mulard M, Chaby G, Le Guyadec T, Estève E, Goujon-Henry C, Parier J, Barthelemy H, Bégon E, Steiner HG, Bénéton N, Boyé T, Mery-Bossard L, Schmutz JL, Bravard P, Sigal M-L, GEM RESOPSO (2017) Socioeconomic inequalities and severity of plaque psoriasis at a first consultation in dermatology centers. Acta Derm Venereol 97(5):632–638. https://doi.org/10.2340/00015555-2625CrossRefPubMed

Galobardes B, Shaw M, Lawlor DA, Lynch JW, Davey Smith G (2006) Indicators of socioeconomic position (part 1). J Epidemiol Community Health 60:7–12CrossRefPubMedPubMedCentral

Dalamaga M (2013) Adipocytokines and psoriasis: insights into mechanisms linking obesity and inflammation to psoriasis. World J Dermatol 2:27CrossRef

Cohen AK, Rai M, Rehkopf DH, Abrams B (2013) Educational attainment and obesity: a systematic review. Obes Rev 14(12):989–1005. https://doi.org/10.1111/obr.12062CrossRefPubMedPubMedCentral

Griffiths CE, Barker JN (2007) Pathogenesis and clinical features of psoriasis. Lancet 370(9583):263–271. https://doi.org/10.1016/S0140-6736(07)61128-3CrossRefPubMed

Title: Causal effect of educational attainment on psoriasis risk mediated by obesity-related traits: Mendelian randomization study
Authors: Qianqian Dai
Yanfeng Zhang
Qian Liu
Chijin Zhang
Publication date: 01-01-2024
Publisher: Springer Berlin Heidelberg
Keywords: Vulgar Psoriasis
Obesity
Obesity
Published in: Archives of Dermatological Research / Issue 1/2024
Print ISSN: 0340-3696
Electronic ISSN: 1432-069X
DOI: https://doi.org/10.1007/s00403-023-02780-6

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Causal effect of educational attainment on psoriasis risk mediated by obesity-related traits: Mendelian randomization study

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