Skip to main content
Top
Published in: European Archives of Oto-Rhino-Laryngology 11/2009

01-11-2009 | Laryngology

Vocal symptoms and acoustic changes in relation to the expanded disability status scale, duration and stage of disease in patients with multiple sclerosis

Authors: Bassem Yamout, Nabil Fuleihan, Taghrid Hajj, Abla Sibai, Omar Sabra, Hani Rifai, Abdul-Latif Hamdan

Published in: European Archives of Oto-Rhino-Laryngology | Issue 11/2009

Login to get access

Abstract

Vocal symptoms and acoustic measures of patients with multiple sclerosis (MS) are investigated in relation to the duration of the disease, stage of the disease and the degree of disability. Eighty-two patients were enrolled in this study (40 MS, 42 controls). In the MS group, the most common vocal symptoms were vocal breaks and vocal fatigue present in 10. None of the patients in the control group had voice breaks. In the male group, there was a significant decrease in the fundamental frequency, habitual pitch and maximum phonation time with a significant increase in Shimmer. In the female group, there was a significant decrease in the maximum phonation time only. There was no correlation between vocal symptoms and acoustic measures versus duration of the disease and extent of disability except for vocal fatigue which significantly associated with EDSS (expanded disability status scale) score. Patients with MS may develop vocal symptoms irrespective of the EDSS score, duration and stage of the disease. Vocal fatigue and vocal breaks are more common than hoarseness.
Literature
4.
go back to reference Darley F, Brown J, Goldstein N (1972) Dysarthria in multiple sclerosis. J Speech Hear Res 15:229–245PubMed Darley F, Brown J, Goldstein N (1972) Dysarthria in multiple sclerosis. J Speech Hear Res 15:229–245PubMed
5.
go back to reference Guberman A (1994) An introduction to clinical neurology: pathophysiology, diagnosis, and treatment. Little, Brown, Boston Guberman A (1994) An introduction to clinical neurology: pathophysiology, diagnosis, and treatment. Little, Brown, Boston
6.
go back to reference Hartelius L, Svensson P (1994) Speech and swallowing symptoms associated with Parkinson’s disease and multiple sclerosis: a survey. Folia Phoniatr Logop 46:9–17PubMedCrossRef Hartelius L, Svensson P (1994) Speech and swallowing symptoms associated with Parkinson’s disease and multiple sclerosis: a survey. Folia Phoniatr Logop 46:9–17PubMedCrossRef
7.
go back to reference Matthews WB, Compston A, Allen IV et al (1991) McAlpine’s multiple sclerosis, 2nd edn. Churchill, London, pp 43–105 Matthews WB, Compston A, Allen IV et al (1991) McAlpine’s multiple sclerosis, 2nd edn. Churchill, London, pp 43–105
8.
go back to reference Holstege G, Ehling T (1996) Two motor systems involved in the production of speech. In: Davis PJ, Fletcher NH (eds) Vocal fold physiology—controlling complexity and chaos. Singular, California, pp 153–169 Holstege G, Ehling T (1996) Two motor systems involved in the production of speech. In: Davis PJ, Fletcher NH (eds) Vocal fold physiology—controlling complexity and chaos. Singular, California, pp 153–169
9.
go back to reference Ramig LA, Scherer RC, Titze IR, Ringell SR (1988) Acoustic analysis of voices of patients with neurologic disease: rationale and preliminary data. Ann Otol Laryngol 97:164–172 Ramig LA, Scherer RC, Titze IR, Ringell SR (1988) Acoustic analysis of voices of patients with neurologic disease: rationale and preliminary data. Ann Otol Laryngol 97:164–172
10.
go back to reference Kurtzke JF (1983) Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 33(11):1444–1452PubMed Kurtzke JF (1983) Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 33(11):1444–1452PubMed
11.
go back to reference Norusis MJ SPSS/PC+ advanced statistics 13.0 Chicago: SPSS. Inc, 2004 Norusis MJ SPSS/PC+ advanced statistics 13.0 Chicago: SPSS. Inc, 2004
12.
go back to reference Langer-Gould A, Popat RA, Huang SM, Cobb K, Fontoura P, Gould MK, Nelson LM (2006) Clinical and demographic predictors of long-term disability in patients with relapsing-remitting multiple sclerosis: a systematic review. Arch Neurol 63(12):1686–1691. doi:10.1001/archneur.63.12.1686 PubMedCrossRef Langer-Gould A, Popat RA, Huang SM, Cobb K, Fontoura P, Gould MK, Nelson LM (2006) Clinical and demographic predictors of long-term disability in patients with relapsing-remitting multiple sclerosis: a systematic review. Arch Neurol 63(12):1686–1691. doi:10.​1001/​archneur.​63.​12.​1686 PubMedCrossRef
13.
go back to reference Hast MH, Fischer JM, Wetzel AB, Thompson VE (1974) Cortical motor representation of the laryngeal muscles in Macaca mulatta 73:229–240 Hast MH, Fischer JM, Wetzel AB, Thompson VE (1974) Cortical motor representation of the laryngeal muscles in Macaca mulatta 73:229–240
14.
go back to reference Brodal A (1983) Neurological anatomy in relation to clinical medicine. Edition 1983, 3rd edn. Oxford University Press, Oxford Brodal A (1983) Neurological anatomy in relation to clinical medicine. Edition 1983, 3rd edn. Oxford University Press, Oxford
15.
go back to reference Yoshida Y, Yatake K, Tanaka Y, Imamura R, Fukunaga H, Nagashima T, Hirano M (1998) Morphological observation of laryngeal motoneurons by means of cholera toxin B subunit tracing technique. Acta Otolaryngol Suppl) 539:98–105CrossRef Yoshida Y, Yatake K, Tanaka Y, Imamura R, Fukunaga H, Nagashima T, Hirano M (1998) Morphological observation of laryngeal motoneurons by means of cholera toxin B subunit tracing technique. Acta Otolaryngol Suppl) 539:98–105CrossRef
20.
go back to reference Hallpike JF, Adams CWM (1983) Tourtellotte WW multiple sclerosis: pathology, diagnosis and management, vol 1. pp 1–29 Hallpike JF, Adams CWM (1983) Tourtellotte WW multiple sclerosis: pathology, diagnosis and management, vol 1. pp 1–29
21.
go back to reference Hartelius L, Runmarker B, Andersen O (2000) Prevalence and characteristics of dysarthria in a multiple sclerosis incidence cohort: relation to neurological data. Folia Phoniatr Logop 52(4):160–177. doi:10.1159/000021531 PubMedCrossRef Hartelius L, Runmarker B, Andersen O (2000) Prevalence and characteristics of dysarthria in a multiple sclerosis incidence cohort: relation to neurological data. Folia Phoniatr Logop 52(4):160–177. doi:10.​1159/​000021531 PubMedCrossRef
22.
23.
go back to reference Klugman TM, Ross E (2002) Perceptions of the impact of speech, language, swallowing, and hearing difficulties on quality of life of a group of South African persons with multiple sclerosis. Folia Phoniatr Logop 54(4):201–221. doi:10.1159/000063194 PubMedCrossRef Klugman TM, Ross E (2002) Perceptions of the impact of speech, language, swallowing, and hearing difficulties on quality of life of a group of South African persons with multiple sclerosis. Folia Phoniatr Logop 54(4):201–221. doi:10.​1159/​000063194 PubMedCrossRef
24.
go back to reference Muzeyyen D, Ipek M, Mine Almaz Y et al (2006) Objective and subjective evaluation of voice quality in multiple sclerosis. J Voice June 29 [Epub ahead of print] Muzeyyen D, Ipek M, Mine Almaz Y et al (2006) Objective and subjective evaluation of voice quality in multiple sclerosis. J Voice June 29 [Epub ahead of print]
26.
go back to reference Hartelius L, Buder EH, Strand EA (1997) Long-term phonatory instability in individuals with multiple sclerosis. J Speech Lang Hear Res 40(5):1056–1072PubMed Hartelius L, Buder EH, Strand EA (1997) Long-term phonatory instability in individuals with multiple sclerosis. J Speech Lang Hear Res 40(5):1056–1072PubMed
Metadata
Title
Vocal symptoms and acoustic changes in relation to the expanded disability status scale, duration and stage of disease in patients with multiple sclerosis
Authors
Bassem Yamout
Nabil Fuleihan
Taghrid Hajj
Abla Sibai
Omar Sabra
Hani Rifai
Abdul-Latif Hamdan
Publication date
01-11-2009
Publisher
Springer-Verlag
Published in
European Archives of Oto-Rhino-Laryngology / Issue 11/2009
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-009-1003-y

Other articles of this Issue 11/2009

European Archives of Oto-Rhino-Laryngology 11/2009 Go to the issue