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Graefe's Archive for Clinical and Experimental Ophthalmology

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01-05-2021 | Vitrectomy | Basic Science

Experimental assessment of the performance of vitreous cutters with fluids with different rheological properties

Authors: Irene Nepita, Rodolfo Repetto, Andrea Dodero, Silvia Vicini, Mariantonia Ferrara, Mario R. Romano, Alessandro Stocchino

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 5/2021

Abstract

Purpose

To assess the influence of rheological properties of an artificial vitreous (AV) on the performance of double-blade (DB) and single-blade (SB) guillotine vitreous cutters, with 23-, 25-, and 27-gauge (G) probes.

Methods

We evaluate the aspiration flow rate, using an optical method, based on image processing. Experiments are conducted using ten viscoelastic vitreous phantoms, with different properties that are measured with rheological tests.

Results

Aspiration rate strongly varies with fluid properties. Regardless of cutter geometry and operational conditions, the flow rate significantly decreases as vitreous viscosity and elasticity increase.

Conclusions

All tested vitreous probes are very sensitive to changes in fluid rheology. SB cutters produce smaller flow rates compared with DB ones of the same caliber; however, they are less sensitive to fluid properties at low aspiration pressures. The use of vitreous substitutes for test performance guarantees comparability between flow rate results achieved with different vitrectomy systems operating in different media. This outcome is further confirmed by the low values of estimated flow rate relative errors.

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Title: Experimental assessment of the performance of vitreous cutters with fluids with different rheological properties
Authors: Irene Nepita
Rodolfo Repetto
Andrea Dodero
Silvia Vicini
Mariantonia Ferrara
Mario R. Romano
Alessandro Stocchino
Publication date: 01-05-2021
Publisher: Springer Berlin Heidelberg
Keyword: Vitrectomy
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 5/2021
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-020-05061-4

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Experimental assessment of the performance of vitreous cutters with fluids with different rheological properties

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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