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Graefe's Archive for Clinical and Experimental Ophthalmology

05-04-2024 | Vitrectomy | Retinal Disorders

Bilateral vitrectomy in patients with proliferative diabetic retinopathy—characteristics and surgical outcomes

Authors: Yun Hsia, Chung-May Yang

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology

Abstract

Purpose

Comparing characteristics and outcomes of patients with bilateral proliferative diabetic retinopathy (PDR) undergoing concurrent and sequential vitrectomy.

Methods

Patients having bilateral vitrectomy were classified into concurrent (requiring bilateral surgery simultaneously) and sequential (indicating vitrectomy in one eye later) groups. Clinical characteristics and outcomes were compared, and correlation between the first and second-operated eyes was analyzed.

Results

One hundred eight and 126 eyes were in the concurrent and sequential groups, respectively. The sequential group was older (50 vs. 45 years, P = 0.017), had less retinal detachment (54 vs. 77%, P < 0.001), and better visual outcomes (0.79 vs. 1.30, P = 0.021), especially the second-operated eyes. The concurrent group had weaker correlations of disease severity (phi coefficient: 0.36 vs. 0.61) and post-operative visual acuity (r: 0.12 vs. 0.34) between the first- and second-operated eyes than the sequential group. Prior intravitreal injection of anti-vascular endothelial growth factor (odds ratio [OR] 0.37, 95% confidence interval [CI] 0.15–0.86, P = 0.025) predicted better outcomes, while post-operative neovascular glaucoma predicted worse outcomes (OR 6.5, 95% CI 1.7–27.9, P = 0.008).

Conclusions

PDR patients requiring surgery concurrently were younger and had more severe diseases and worse outcomes. However, poor outcomes in the first eye did not predict similar outcomes in the second eye.

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Title: Bilateral vitrectomy in patients with proliferative diabetic retinopathy—characteristics and surgical outcomes
Authors: Yun Hsia
Chung-May Yang
Publication date: 05-04-2024
Publisher: Springer Berlin Heidelberg
Keywords: Vitrectomy
Diabetic Retinopathy
Diabetic Retinopathy
Retinal Detachment
Glaucoma
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-024-06462-5

At a glance: The STEP trials

Springer Medicine

Bilateral vitrectomy in patients with proliferative diabetic retinopathy—characteristics and surgical outcomes

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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