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01-07-2011 | Letter to the Editor

Vitamin D depletion: of clinical significance in advanced cancer?

Authors: Carol A. Stone, Rose Anne Kenny, Martin Healy, J. Bernard Walsh, Peter G. Lawlor

Published in: Supportive Care in Cancer | Issue 7/2011

Excerpt

Evidence has been emerging from laboratory-based and epidemiological studies, over the past two decades, to suggest that that vitamin D has a much bigger role than previously thought; most tissues and cells in the body have vitamin D receptors and many others, in addition to the kidneys, have the capacity to hydroxylate 25-hydroxyvitamin D to the active 1,25-hydroxyvitamin D (1,25-(OH)₂D). Data from observational population-based and preclinical studies implicate vitamin D deficiency in the pathogenesis of cancers, autoimmune and other common diseases [1‐3]. …

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Title: Vitamin D depletion: of clinical significance in advanced cancer?
Authors: Carol A. Stone
Rose Anne Kenny
Martin Healy
J. Bernard Walsh
Peter G. Lawlor
Publication date: 01-07-2011
Publisher: Springer-Verlag
Published in: Supportive Care in Cancer / Issue 7/2011
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-011-1117-9

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