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Published in: European Journal of Nuclear Medicine and Molecular Imaging 4/2005

01-04-2005 | Image of the Month

Visualisation of impaired dopamine biosynthesis in a case of aromatic l-amino acid decarboxylase deficiency by co-registered 18F-FDOPA PET and magnetic resonance imaging

Authors: Hung-Jen Hsieh, Sheng-Hsiang Lin, Hon-Man Liu

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 4/2005

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Excerpt

Aromatic l-amino acid decarboxylase (AADC) converts l-dopa to dopamine and 5-hydroxytryptophan to serotonin. Deficiency of this enzyme, a rare autosomal recessive disorder, leads to decreased brain levels of these neurotransmitters and resultant developmental disorder.
Metadata
Title
Visualisation of impaired dopamine biosynthesis in a case of aromatic l-amino acid decarboxylase deficiency by co-registered 18F-FDOPA PET and magnetic resonance imaging
Authors
Hung-Jen Hsieh
Sheng-Hsiang Lin
Hon-Man Liu
Publication date
01-04-2005
Publisher
Springer-Verlag
Published in
European Journal of Nuclear Medicine and Molecular Imaging / Issue 4/2005
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI
https://doi.org/10.1007/s00259-004-1618-6

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