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Virchows Archiv

Issue 3/2022

Content (18 Articles)

Open Access NSCLC Review and Perspectives

Expert opinion on NSCLC small specimen biomarker testing — Part 1: Tissue collection and management

Frédérique Penault-Llorca, Keith M. Kerr, Pilar Garrido, Erik Thunnissen, Elisabeth Dequeker, Nicola Normanno, Simon J. Patton, Jenni Fairley, Joshua Kapp, Daniëlle de Ridder, Aleš Ryška, Holger Moch

Open Access NSCLC Review and Perspectives

Expert opinion on NSCLC small specimen biomarker testing — Part 2: Analysis, reporting, and quality assessment

Frédérique Penault-Llorca, Keith M. Kerr, Pilar Garrido, Erik Thunnissen, Elisabeth Dequeker, Nicola Normanno, Simon J. Patton, Jenni Fairley, Joshua Kapp, Daniëlle de Ridder, Aleš Ryška, Holger Moch

Breast Cancer Original Article

Computational portraits of the tumoral microenvironment in human breast cancer

Dongling Wu, Sean M. Hacking, Hector Chavarria, Mohammed Abdelwahed, Mansoor Nasim

Open Access Prostate Cancer Original Article

The significance of the extent of tissue embedding for the detection of incidental prostate carcinoma on transurethral prostate resection material: the more, the better?

Jens Köllermann, Benedikt Hoeh, Daniel Ruppel, Kevin Smith, Henning Reis, Mike Wenzel, Felix Preisser, Marina Kosiba, Philipp Mandel, Pierre I. Karakiewicz, Andreas Becker, Felix K. H. Chun, Peter Wild, Luis A. Kluth

Urothelial Cancer Original Article

Uroplakin II as a single marker for luminal versus basal molecular subtypes in muscle invasive urothelial carcinoma

Collin Pryma, Carlos Villamil, Ewan A. Gibb, Htoo Zarni Oo, Roland Seiler, Alberto Contreras-Sanz, James Douglas, Peter C. Black, Gang Wang

Open Access Metastasis Original Article

Pathological processing of sentinel lymph nodes in endometrial carcinoma — routine aspects of grossing, ultra-staging, and surgico-pathological parameters in a series of 833 lymph nodes

Tilman T. Rau, Mona V. Deppeler, Lucine Christe, Franziska Siegenthaler, Sara Imboden, Andrea Papadia, Michael D. Mueller

Carcinoid Tumor Original Article

Human epididymis protein 4 (HE4) is a novel immunohistochemical marker of neuroendocrine differentiation

Wenjing Su, Kun Yang, Huifeng Jiang, Haiyun Song, Kun Feng, Qiuyao Li

Original Article

Deglycosylation of pathological specimens alters performance of diagnostic PDL1 antibodies

Franz F. Dressler, Devang S. Dabadghao, Luise Klapper, Sven Perner, Christian Idel, Julika Ribbat-Idel

Correction

Correction to: Deglycosylation of pathological specimens alters performance of diagnostic PDL1 antibodies

Franz F. Dressler, Devang S. Dabadghao, Luise Klapper, Sven Perner, Christian Idel, Julika Ribbat-Idel

Original Article

Neutrophil extracellular traps enriched with IL-1β and IL-17A participate in the hepatic inflammatory process of patients with non-alcoholic steatohepatitis

Stella Arelaki, Triantafyllia Koletsa, Emmanuil Sinakos, Vasileios Papadopoulos, Konstantinos Arvanitakis, Panagiotis Skendros, Evangelos Akriviadis, Konstantinos Ritis, Georgios Germanidis, Prodromos Hytiroglou

Open Access Endoscopy Original Article

Predictive value of p53, Ki67 and TLR5 in neoplastic progression of Barrett’s esophagus: a matched case–control study

Olli Helminen, Jukka Melkko, Juha Saarnio, Eero Sihvo, Teijo Kuopio, Pasi Ohtonen, Joonas H. Kauppila, Tuomo J. Karttunen, Heikki Huhta

Esophageal Cancer Original Article

Clinicopathological and mutational analysis of esophageal basaloid squamous cell carcinoma

Yuka Yanai, Takuo Hayashi, Sho Tsuyama, Motomi Nasu, Takashi Hashimoto, Yoshiaki Kajiyama, Masahiko Tsurumaru, Shinji Mine, Hajime Orita, Tetsu Fukunaga, Takashi Yao, Tsuyoshi Saito

Open Access Lymphoma Original Article

H3K27m3 overexpression as a new, BCL2 independent diagnostic tool in follicular and cutaneous follicle center lymphomas

Magdalena M. Brune, Visar Vela, Ivana Bratic Hench, Susanne Dertinger, Vanessa Borgmann, Stefan Dirnhofer, Alexandar Tzankov

A novel EWSR1-HOXB13 rearrangement in a fibroblastic tumor from the abdomen of a young woman

Harumi Nakamura, Yoji Kukita, Hironari Tamiya, Satoshi Takenaka, Toshinari Yagi

Autopsy Brief Report

Impact of the COVID-19 pandemic on pathology training: a survey among Spanish residents

Irene Carretero-Barrio, Joan Lop-Gros, Mar Iglesias, Carolina Martínez, Xavier Matias-Guiu, Belén Pérez-Mies, José Palacios

Kidney Cancer Brief Report

A primary rectal neoplasm with novel DDX5-TFEB fusion

Mengxin Zhang, Xiaoxue Yin, Junru Chen, Sha Zhu, Linmao Zheng, Hao Zeng, Qiao Zhou, Ni Chen