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Child's Nervous System

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27-10-2023 | Vestibular Schwannoma | Original Article

Sporadic vestibular schwannoma in a pediatric population: a case series

Authors: Nikitha Kosaraju, Lindsay S. Moore, Jip Y. Mulders, Nikolas H. Blevins

Published in: Child's Nervous System | Issue 3/2024

Abstract

Purpose

To describe the characteristics, management, and outcomes of pediatric patients with sporadic vestibular schwannoma (sVS).

Methods

This was a case series at a tertiary care center. Patients were identified through a research repository and chart review. Interventions were microsurgery, stereotactic radiosurgery (SRS), and observation. Outcome measures were tumor control, facial nerve function, and hearing.

Results

Eight patients over 2006–2022 fulfilled inclusion criteria (unilateral VS without genetic or clinical evidence of neurofibromatosis type 2 (NF2); age ≤ 21) with a mean age of 17 years (14–20). Average greatest tumor length in the internal auditory canal was 9.7 mm (4.0–16.1). Average greatest tumor dimension (4/8 tumors) in the cerebellopontine angle was 19.1 mm (11.3–26.8). Primary treatment was microsurgery in five (62.5%) patients, observation in two (25%), and SRS in one (12.5%). Four (80%) surgical patients had gross total resections, and one (20%) had regrowth post-near total resection and underwent SRS. One observed patient and the primary SRS patient have remained radiographically stable for 3.5 and 7 years, respectively. The other observed patient required surgery for tumor growth after 12 months of observation. Two surgical patients had poor facial nerve outcomes. All post-procedural patients developed anacusis. Mean follow-up was 3 years (0.5–7).

Conclusions

We describe one of the largest reported cohorts of pediatric sVS in the USA. Diligent exclusion of NF2 is critical. Given the high likelihood of eventually requiring intervention and known adverse effects of SRS, microsurgery remains the preferred treatment. However, observation can be considered in select situations.

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Title: Sporadic vestibular schwannoma in a pediatric population: a case series
Authors: Nikitha Kosaraju
Lindsay S. Moore
Jip Y. Mulders
Nikolas H. Blevins
Publication date: 27-10-2023
Publisher: Springer Berlin Heidelberg
Keywords: Vestibular Schwannoma
Vestibular Schwannoma
Published in: Child's Nervous System / Issue 3/2024
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI: https://doi.org/10.1007/s00381-023-06184-9

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Springer Medicine

Sporadic vestibular schwannoma in a pediatric population: a case series

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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