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European Archives of Oto-Rhino-Laryngology

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06-01-2024 | Vestibular Schwannoma | Otology

Analysis of the association between vestibular schwannoma and hearing status using a newly developed radiomics technique

Authors: Kang Hyeon Lim, Seung-hak Lee, Insik Song, Hee Soo Yoon, Hong Jin Kim, Ye Hwan Lee, Eunjin Kim, Yoon Chan Rah, June Choi

Published in: European Archives of Oto-Rhino-Laryngology | Issue 6/2024

Abstract

Purpose

Vestibular schwannoma is a benign tumor originating from Schwann cells surrounding the eighth cranial nerve and can cause hearing loss, tinnitus, balance problems, and facial nerve disorders. Because of the slow growth of the tumor, predicting the hearing function of patients with vestibular schwannoma’s is important to obtain information that would be useful for deciding the treatment modality. This study aimed to analyze the association between magnetic resonance imaging features and hearing status using a new radiomics technique.

Methods

We retrospectively analyzed 115 magnetic resonance images and hearing results from 73 patients with vestibular schwannoma. A total of 70 radiomics features from each tumor volume were calculated using T1-weighted magnetic resonance imaging. Radiomics features were classified as histogram-based, shape-based, texture-based, and filter-based. The least absolute shrinkage and selection operator method was used to select the radiomics features among the 70 features that best predicted the hearing test. To ensure the stability of the selected features, the least absolute shrinkage and selection operator method was repeated 10 times. Finally, features set five or more times were selected as radiomics signatures.

Results

The radiomics signatures selected using the least absolute shrinkage and selection operator method were: minimum, variance, maximum 3D diameter, size zone variance, log skewness, skewness slope, and kurtosis slope. In random forest, the mean performance was 0.66 (0.63–0.77), and the most important feature was Log skewness.

Conclusions

Newly developed radiomics features are associated with hearing status in patients with vestibular schwannoma and could provide information when deciding the treatment modality.

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Title: Analysis of the association between vestibular schwannoma and hearing status using a newly developed radiomics technique
Authors: Kang Hyeon Lim
Seung-hak Lee
Insik Song
Hee Soo Yoon
Hong Jin Kim
Ye Hwan Lee
Eunjin Kim
Yoon Chan Rah
June Choi
Publication date: 06-01-2024
Publisher: Springer Berlin Heidelberg
Keywords: Vestibular Schwannoma
Vestibular Schwannoma
Magnetic Resonance Imaging
Magnetic Resonance Imaging
Schwannoma
Published in: European Archives of Oto-Rhino-Laryngology / Issue 6/2024
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-023-08410-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Analysis of the association between vestibular schwannoma and hearing status using a newly developed radiomics technique

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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