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Acta Neurochirurgica

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01-09-2019 | Vestibular Schwannoma | Original Article - Tumor - Schwannoma

Fatigue in patients with vestibular schwannoma

Authors: Dhanushan Dhayalan, Morten Lund-Johansen, Monica Finnkirk, Øystein Vesterli Tveiten

Published in: Acta Neurochirurgica | Issue 9/2019

Abstract

Background

Patients with vestibular schwannoma (VS) often complain about tiredness, exhaustion, lack of energy, and strength, but such symptoms of fatigue have scarcely been objectified and analyzed in a VS population. We aimed to characterize fatigue in a cohort of patients with VS and compare such symptoms with a control group.

Methods

All patients who attended an educational course for patients with VS were surveyed with validated tools for assessment of fatigue (fatigue severity scale), anxiety and depression (hospital anxiety and depression scale), sleepiness (Epworth sleepiness scale), and apathy (Starkstein apathy scale). Quality of Life was assessed with the disease-specific Penn Acoustic Neuroma Quality of Life (PANQOL). Symptom severity was estimated with a visual analog scale (VAS). The results have been compared to a control group consisting of patient companions.

Results

Data from 88 VS patients and 49 controls were analyzed. The controls had similar age and sex distribution as patients. Fifty-seven percent of VS patients had significant fatigue, compared to 25% in the control group. The mean fatigue score was 4.1 for the patients, and 2.8 for controls. Patients with fatigue were more likely to have depression, anxiety, sleepiness, and apathy. No correlation of fatigue was found with age, gender, or treatment modality. Regression analyses revealed depression, apathy, and vertigo to be predictors of fatigue. Fatigue was strongly correlated to QoL.

Conclusion

Almost six out of ten VS patients had fatigue, significantly higher than the control group. Interest and focus on fatigue in VS patients can improve the patient’s QoL.

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Title: Fatigue in patients with vestibular schwannoma
Authors: Dhanushan Dhayalan
Morten Lund-Johansen
Monica Finnkirk
Øystein Vesterli Tveiten
Publication date: 01-09-2019
Publisher: Springer Vienna
Keywords: Vestibular Schwannoma
Mood Disorders
Vestibular Schwannoma
Affective Disorder
Anxiety
Fatigue
Published in: Acta Neurochirurgica / Issue 9/2019
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI: https://doi.org/10.1007/s00701-019-04003-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Fatigue in patients with vestibular schwannoma

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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