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Published in: Journal of Gastrointestinal Surgery 1/2016

01-01-2016

Venous Thromboembolism Prophylaxis in Liver Surgery

Authors: Thomas A. Aloia, William H. Geerts, Bryan M. Clary, Ryan W. Day, Alan W. Hemming, Luiz Carneiro D’Albuquerque, Charles M. Vollmer Jr., Jean-Nicolas Vauthey, Giles J. Toogood

Published in: Journal of Gastrointestinal Surgery | Issue 1/2016

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Abstract

Background

At a recently concluded Americas Hepato-Pancreato-Biliary Association Annual Meeting, a Clinical Practice Guidelines Conference Series was convened with the topic focusing on Venous Thromboembolism (VTE) Prophylaxis in Liver Surgery. The symposium brought together hepatobiliary surgeons from three continents as well as medical experts in hematology and coagulation.

Methods

The content of the discussion included literature reviews, evaluation of multi-institutional VTE outcome data, and examination of practice patterns at multiple high-volume centers.

Results

Literature review demonstrated that, within gastrointestinal surgery, liver resection patients are at particularly high-risk for VTE. Recent evidence clearly indicates a direct relationship between the magnitude of hepatectomy and postoperative VTE rates, however, the PT/INR does not accurately reflect the coagulation status of the post-hepatectomy patient. Evaluation of available data and practice patterns regarding the utilization and timing of anticoagulant VTE prophylaxis led to recommendations regarding preoperative and postoperative thromboprophylaxis for liver surgery patients.

Conclusions

This conference was effective in consolidating our knowledge of coagulation abnormalities after liver resection. Based on the expert review of the available data and practice patterns, a number of recommendations were developed.
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Metadata
Title
Venous Thromboembolism Prophylaxis in Liver Surgery
Authors
Thomas A. Aloia
William H. Geerts
Bryan M. Clary
Ryan W. Day
Alan W. Hemming
Luiz Carneiro D’Albuquerque
Charles M. Vollmer Jr.
Jean-Nicolas Vauthey
Giles J. Toogood
Publication date
01-01-2016
Publisher
Springer US
Published in
Journal of Gastrointestinal Surgery / Issue 1/2016
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-015-2902-4

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