Published in:
Open Access
01-12-2016 | Workshop presentation
Venous oxygen saturation estimation from multiple T2 maps with varying inter-echo spacing
Authors:
Juliet Varghese, Rizwan Ahmad, Ning Jin, Lee C Potter, Orlando P Simonetti
Published in:
Journal of Cardiovascular Magnetic Resonance
|
Special Issue 1/2016
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Excerpt
Dependence of blood T2 on O2 saturation has led to non-invasive MRI-based techniques for determining venous O2 saturation (SvO
2) [1-3]. However, applying a general calibration factor derived from in vitro experiments can lead to inaccurate and largely varying SvO
2 estimates in the target population. We aim to show that based on the Luz-Meiboom relation 1/T2 = 1/T2o + Hct(1-Hct) τ
ex[(1-%SO
2/100)αω
0]
2(1-2*τ
ex/τ
180 tanh(τ
180/2*τ
ex))[
4], individual SvO
2 can be determined from multiple T2 maps, each acquired at a specific inter-echo spacing (τ
180). …