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European Radiology

Published in:

01-05-2019 | Editorial

Variability in quantitative diffusion-weighted MR imaging (DWI) across different scanners and imaging sites: is there a potential consensus that can help reducing the limits of expected bias?

Author: Frederic Carsten Schmeel

Published in: European Radiology | Issue 5/2019

Abstract

Key Points

• Variability of ADC measurements may be substantial across different MRI scanners and imaging sites.

• DWI protocol standardization and increased awareness of frequent sources of error can help reducing the limits of expected bias.

• Focusing on ADC change and normalized ADC values rather than on absolute measurements can facilitate consistent use of ADC in multi-center studies.

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Winfield JM, Collins DJ, Priest AN et al (2016) A framework for optimization of diffusion-weighted MRI protocols for large field-of-view abdominal-pelvic imaging in multicenter studies. Med Phys 43:95–110CrossRefPubMed

Sasaki M, Yamada K, Watanabe Y et al (2008) Variability in absolute apparent diffusion coefficient values across different platforms may be substantial: a multivendor, multi-institutional comparison study. Radiology 249:624–630CrossRefPubMed

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Malyarenko D, Galbán CJ, Londy FJ et al (2013) Multi-system repeatability and reproducibility of apparent diffusion coefficient measurement using an ice-water phantom. J Magn Reson Imaging 37:1238–1246CrossRefPubMed

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10.

Pathak R, Ragheb H, Thacker NA et al (2017) A data-driven statistical model that estimates measurement uncertainty improves interpretation of ADC reproducibility: a multi-site study of liver metastases. Sci Rep 26:14084CrossRef

Title: Variability in quantitative diffusion-weighted MR imaging (DWI) across different scanners and imaging sites: is there a potential consensus that can help reducing the limits of expected bias?
Author: Frederic Carsten Schmeel
Publication date: 01-05-2019
Publisher: Springer Berlin Heidelberg
Published in: European Radiology / Issue 5/2019
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-018-5866-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Variability in quantitative diffusion-weighted MR imaging (DWI) across different scanners and imaging sites: is there a potential consensus that can help reducing the limits of expected bias?

Abstract

Key Points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Key Points

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