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European Radiology

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Open Access 01-07-2010 | Head and Neck

Value of MR imaging in the differentiation of benign and malignant orbital tumors in adults

Authors: Junfang Xian, Zhengyu Zhang, Zhenchang Wang, Jing Li, Bentao Yang, Fengyuan Man, Qinglin Chang, Yunting Zhang

Published in: European Radiology | Issue 7/2010

Abstract

Purpose

To prospectively evaluate magnetic resonance (MR) imaging including dynamic contrast-enhanced MR imaging in the differentiation of benign from malignant orbital masses and to evaluate which MR imaging features are most predictive of malignant tumors.

Materials and methods

The study was approved by the institutional review board and signed informed consent was obtained. Nonenhanced, static, and dynamic contrast-enhanced MR imaging was performed in 102 adult patients with an orbital mass. Diagnosis was based on histologic findings. MR imaging features of benign and malignant orbital lesions were evaluated correlated with histological findings. Multivariate logistic regression analysis was employed to identify the best combination of MR imaging features that might be predictive of malignancy.

Results

Nonenhanced, static, and dynamic enhancement MR imaging was significantly superior to two other models in prediction of malignancy (p < 0.05). Multivariate logistic regression analysis identified that the most discriminating MR imaging features were isointense mass on T2-weighted imaging and a washout-type time–intensity curve for both observers.

Conclusion

Nonenhanced, static, and dynamic enhancement MR imaging improved differentiation between benign and malignant orbital masses in adult patients.

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Title: Value of MR imaging in the differentiation of benign and malignant orbital tumors in adults
Authors: Junfang Xian
Zhengyu Zhang
Zhenchang Wang
Jing Li
Bentao Yang
Fengyuan Man
Qinglin Chang
Yunting Zhang
Publication date: 01-07-2010
Publisher: Springer-Verlag
Published in: European Radiology / Issue 7/2010
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-009-1711-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Value of MR imaging in the differentiation of benign and malignant orbital tumors in adults

Abstract

Purpose

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Materials and methods

Results

Conclusion

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