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Archives of Gynecology and Obstetrics

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01-01-2014 | Reproductive Medicine

Value of follicular fluid vitamin D in predicting the pregnancy rate in an IVF program

Authors: Razieh Dehghani Firouzabadi, Elham Rahmani, Mozhgan Rahsepar, Mohammad Mahdavi Firouzabadi

Published in: Archives of Gynecology and Obstetrics | Issue 1/2014

Abstract

Purpose

This study investigated whether there is a correlation between levels of 25OH-D in the follicular fluid and the serum of infertile women and the results of IVF and rates of pregnancy. The association between the levels of 25OH-D in the follicular fluid and the vitamin D repletion status was also assessed.

Methods

Two hundred and twenty-one infertile women participated in an IVF cycle from 2010 to 2011 in a prospective observational study. Serum and follicular fluid were collected for vitamin D analysis. Deficient, insufficient, and sufficient levels of vitamin D were defined as 10, 10–29, and 30–100 ng/ml, respectively. IVF cycle parameters and clinical pregnancy rates were also compared with the vitamin D level.

Results

The levels of vitamin D deficiency, insufficiency, and sufficiency were 22.6, 70.1, and 7.2 %, respectively. The fertilization rates associated with these three levels of vitamin D were 43.17, 53.37, and 58.77 %, respectively, (P = 0.054), and the implantation rates were 17.33, 15.26, and 18.75 %, respectively, (P = 0.579). No significant correlation was seen between the pregnancy rate and the serum vitamin D level (P = 0.094) or the follicular vitamin D level (P = 0.170). The serum and follicular fluid vitamin D levels showed a significant correlation (P = 0.000).

Conclusion

Although vitamin D is an important hormone in the human body, no correlation was found between the serum and follicular vitamin D level and the pregnancy rate in the IVF cycle.

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Title: Value of follicular fluid vitamin D in predicting the pregnancy rate in an IVF program
Authors: Razieh Dehghani Firouzabadi
Elham Rahmani
Mozhgan Rahsepar
Mohammad Mahdavi Firouzabadi
Publication date: 01-01-2014
Publisher: Springer Berlin Heidelberg
Published in: Archives of Gynecology and Obstetrics / Issue 1/2014
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-013-2959-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Value of follicular fluid vitamin D in predicting the pregnancy rate in an IVF program

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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