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BMC Psychiatry
Published in: BMC Psychiatry 1/2011

Open Access 01-12-2011 | Research article

Validity of the 32-item Hypomania Checklist (HCL-32) in a clinical sample with mood disorders in China

Authors: Hai-chen Yang, Cheng-mei Yuan, Tie-bang Liu, Ling-jiang Li, Hong-jun Peng, Chun-ping Liao, Han Rong, Yi-ru Fang, Jules Angst

Published in: BMC Psychiatry | Issue 1/2011

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Abstract

Background

The 32-item Hypomania Checklist (HCL-32), a questionnaire for screening bipolar disorders, has been utilised in several countries, but it unclear if the Chinese version of the HCL-32 is valid.

Methods

Consecutive patients with bipolar disorders (BP, N = 300) and unipolar major depression (UP, N = 156) completed the Chinese version of the HCL-32. The subjects underwent a structured clinical interview for DSM-IV Axis-I disorders (SCID).

Results

The eigenvalues for the first three factors in the HCL-32 were calculated as 5.16 (active/elated), 2.72 (risk-taking) and 2.48 (irritable) using factor analysis. Cronbach's alpha for the HCL-32 was calculated to be 0.88. Positive responses to twenty-eight items were significantly more frequent by patients with BP than those with UP, and the other four items (7th, 21st, 25th and 32nd) showed no such trend. Fourteen was the optimal cut-off for discriminating between BP and UP. The HCL-32 distinguished between BP-II and UP, with 13 being the optimal cut-off. A cut-off of 13 yielded a sensitivity of 0.77 and a specificity of 0.62 between BP and UP.

Conclusions

This study demonstrated that the simplified Chinese version of HCL-32 was valid for patients with mood disorders. The optimal cut-off of 13 for distinguishing between BP-II and UP was valid and could be used to improve the sensitivity of screening BP-II patients when the HCL-32 is used in psychiatric settings in China.
Appendix
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Metadata
Title
Validity of the 32-item Hypomania Checklist (HCL-32) in a clinical sample with mood disorders in China
Authors
Hai-chen Yang
Cheng-mei Yuan
Tie-bang Liu
Ling-jiang Li
Hong-jun Peng
Chun-ping Liao
Han Rong
Yi-ru Fang
Jules Angst
Publication date
01-12-2011
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2011
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/1471-244X-11-84

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