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01-12-2016 | Original Article

Validity of muscle thickness-based prediction equation for quadriceps femoris volume in middle-aged and older men and women

Authors: Miyuki Nakatani, Yohei Takai, Ryota Akagi, Taku Wakahara, Norihide Sugisaki, Megumi Ohta, Yasuo Kawakami, Tetsuo Fukunaga, Hiroaki Kanehisa

Published in: European Journal of Applied Physiology | Issue 11-12/2016

Abstract

Background

This study examined the validity of muscle thickness (MT)-based prediction equation for the muscle volume of the quadriceps femoris (QFMV) by evaluating the applicability of a prediction equation previously derived from young men and by developing a new prediction equation in middle-aged and older individuals.

Methods

The MT at the midpoint of the thigh anterior and QFMV were determined using ultrasonography and magnetic resonance imaging in 30 men and 30 women aged 51 to 77 years. First, we examined the validity of the MT-based prediction equation previously developed for young men to estimate the QFMV of middle-aged and older individuals. Second, we allocated the subjects to validation or cross-validation group and developed a prediction equation for estimating the QFMV using a stepwise multiple regression analysis.

Results

The published equation generated a small but a significant difference between the measured and estimated QFMV, with a systematic error depending on the size of QFMV. A multiple regression analysis for the validation group produced the following equation: QFMV (cm³) = (sex × 267.7) + (MT × 249.3) + (thigh length × 41.1) − 1663.7 (sex: man = 1, woman = 0). R ² and SEE of the regression equation were 0.888 and 124.4 cm³ (12.0 %), respectively. The developed equation was validated and cross-validated.

Conclusion

For middle-aged and older individuals, the prediction equation previously derived from young men is not applicable, and the newly developed prediction equation with sex, MT, and thigh length as independent variables is applicable for estimating QFMV.

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Title: Validity of muscle thickness-based prediction equation for quadriceps femoris volume in middle-aged and older men and women
Authors: Miyuki Nakatani
Yohei Takai
Ryota Akagi
Taku Wakahara
Norihide Sugisaki
Megumi Ohta
Yasuo Kawakami
Tetsuo Fukunaga
Hiroaki Kanehisa
Publication date: 01-12-2016
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Applied Physiology / Issue 11-12/2016
Print ISSN: 1439-6319
Electronic ISSN: 1439-6327
DOI: https://doi.org/10.1007/s00421-016-3464-1

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Validity of muscle thickness-based prediction equation for quadriceps femoris volume in middle-aged and older men and women

Abstract

Background

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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