Skip to main content
Top
Published in: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 1/2015

Open Access 01-12-2015 | Original research

Validity of modified early warning, Glasgow Blatchford, and pre-endoscopic Rockall scores in predicting prognosis of patients presenting to emergency department with upper gastrointestinal bleeding

Authors: Seyran Bozkurt, Ataman Köse, Engin Deniz Arslan, Semra Erdoğan, Enver Üçbilek, İbrahim Çevik, Cüneyt Ayrık, Orhan Sezgin

Published in: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine | Issue 1/2015

Login to get access

Abstract

Background

GBS, MEWS, and PER scoring systems are not commonly used for patients presenting to emergency department with GIS bleeding. This study aimed to determine the value of MEWS, GBS, and PER scores in predicting bleeding at follow-up, endoscopic therapy and blood transfusion need, mortality, and rebleeding within a 1-month period.

Methods

A total of 202 consecutive patients with upper GIS bleeding between July 2013 and November 2014 were prospectively enrolled in the study. The relationship between MEWS, GBS, and PER scores and hospital outcome, bleeding at follow-up, endoscopic therapy, transfusion need, rebleeding, and death were examined.

Results

The study included a total of 202 subjects, with 84 (41.6 %) females and 118 (58.4 %) males. There was a significant correlation between GBS, MEWS, and PER scores and hospital outcomes (p <0.004, p <0.001, p <0.001, respectively). A GBS score greater than 11 succesfully predicted bleeding at follow-up (p = 0.0237). GBS score's sensitivity for predicting endoscopic therapy was greater than those of other scoring systems. The discriminatory power of each scoring system was significant for predicting transfusion (p <0.0001, p = 0.0470, and p = 0.0014, respectively). A GBS score greater than 13, a MEWS score greater than 2, and a PER score greater than 3 predicted death. A PER score greater than 3 predicted rebleeding (p <0.0001).

Conclusion

The scoring systems in question can be easily calculated in patients presenting to ED with upper GIS bleeding and may be beneficial for risk stratification, determination of transfusion need, prediction of rebleeding, and decisions of hospitalization or discharge.
Literature
1.
go back to reference Camellini L, Merighi A, Pagnini C, Azzolini F, Guazzetti S, Scarcelli A, et al. Comparison of three different risk scoring systems in non-variceal upper gastrointestinal bleeding. Dig Liver Dis. 2004;36:271–7.PubMedCrossRef Camellini L, Merighi A, Pagnini C, Azzolini F, Guazzetti S, Scarcelli A, et al. Comparison of three different risk scoring systems in non-variceal upper gastrointestinal bleeding. Dig Liver Dis. 2004;36:271–7.PubMedCrossRef
2.
go back to reference Köksal Ö, Özeren G, Özdemir F, Armağan E, Aydın Ş, Ayyıldız T. Prospective validation of the Glasgow Blatchford scoring system in patients with upper gastrointestinal bleeding in the emergency department. Turk J Gastroenterol. 2012;23(5):448–55.PubMed Köksal Ö, Özeren G, Özdemir F, Armağan E, Aydın Ş, Ayyıldız T. Prospective validation of the Glasgow Blatchford scoring system in patients with upper gastrointestinal bleeding in the emergency department. Turk J Gastroenterol. 2012;23(5):448–55.PubMed
3.
go back to reference Göksu E, Erken O, Erçetin Y, Kılıçaslan I, Çete Y. Factors effecting mortality and demographic properties of patients presenting to the Emergency Department of Akdeniz University Hospital with upper gastrointestinal bleeding. Turk J Emerg Med. 2004;4:121–6. Göksu E, Erken O, Erçetin Y, Kılıçaslan I, Çete Y. Factors effecting mortality and demographic properties of patients presenting to the Emergency Department of Akdeniz University Hospital with upper gastrointestinal bleeding. Turk J Emerg Med. 2004;4:121–6.
4.
go back to reference Wang CH, Chen YW, Young YR, Yang CJ, Chen IC. A prospective comparison of scoring systems in upper gastrointestinal bleeding. Am J Emerg Med. 2013;31:775–8.PubMedCrossRef Wang CH, Chen YW, Young YR, Yang CJ, Chen IC. A prospective comparison of scoring systems in upper gastrointestinal bleeding. Am J Emerg Med. 2013;31:775–8.PubMedCrossRef
5.
go back to reference Lim JK, Ahmed A. Endoscopic approach to the treatment of gastrointestinal bleeding. Tech Vasc Interv Rad. 2004;7:123–9.CrossRef Lim JK, Ahmed A. Endoscopic approach to the treatment of gastrointestinal bleeding. Tech Vasc Interv Rad. 2004;7:123–9.CrossRef
6.
go back to reference Blatchford O, Murray WR, Blatchford M. A risk score to predict need for treatment for uppergastrointestinal haemorrhage. Lancet. 2000;356:1318–21.PubMedCrossRef Blatchford O, Murray WR, Blatchford M. A risk score to predict need for treatment for uppergastrointestinal haemorrhage. Lancet. 2000;356:1318–21.PubMedCrossRef
7.
go back to reference Farooq FT, Lee MH, Das A, Dixit R, Wong RC. Clinical triage decision vs risk scores in predicting the need for endotherapy in upper gastrointestinal bleeding. Am J Emerg Med. 2012;30:129–34.PubMedCrossRef Farooq FT, Lee MH, Das A, Dixit R, Wong RC. Clinical triage decision vs risk scores in predicting the need for endotherapy in upper gastrointestinal bleeding. Am J Emerg Med. 2012;30:129–34.PubMedCrossRef
8.
go back to reference Pang SH, Ching JY, Lau JY, Sung JJ, Graham DY, Chan FK. Comparing the Blatchford and pre-endoscopic Rockall score in predicting the need for endoscopic therapy in patients with upper GI hemorrhage. Gastrointest Endosc. 2010;71:1134–40.PubMedCrossRef Pang SH, Ching JY, Lau JY, Sung JJ, Graham DY, Chan FK. Comparing the Blatchford and pre-endoscopic Rockall score in predicting the need for endoscopic therapy in patients with upper GI hemorrhage. Gastrointest Endosc. 2010;71:1134–40.PubMedCrossRef
9.
go back to reference Ludikhuize J, Smorenburg SM, Rooij SE, Jonge E. Identification of deteriorating patients on general wards; measurement of vital parameters and potential effectiveness of the Modified Early Warning Score. J Crit Care. 2012;27(4):424. e7-13.PubMedCrossRef Ludikhuize J, Smorenburg SM, Rooij SE, Jonge E. Identification of deteriorating patients on general wards; measurement of vital parameters and potential effectiveness of the Modified Early Warning Score. J Crit Care. 2012;27(4):424. e7-13.PubMedCrossRef
10.
go back to reference Fullerton JN, Price CL, Silvey NE, Brace SJ, Perkins GD. Is the Modified Early Warning Score (MEWS) superior to clinician judgement in detecting critical illness in the pre-hospital environment? Resuscitation. 2012;83:557–62.PubMedCrossRef Fullerton JN, Price CL, Silvey NE, Brace SJ, Perkins GD. Is the Modified Early Warning Score (MEWS) superior to clinician judgement in detecting critical illness in the pre-hospital environment? Resuscitation. 2012;83:557–62.PubMedCrossRef
11.
go back to reference Rockall TA. Risk scoring in acute upper gastrointestinal haemorrhage. Dig Liver Dis. 2006;38(1):10–1.PubMedCrossRef Rockall TA. Risk scoring in acute upper gastrointestinal haemorrhage. Dig Liver Dis. 2006;38(1):10–1.PubMedCrossRef
12.
go back to reference Chandra S, Hess EP, Agarwal D, Nestler DM, Montori VM, Song LM, et al. External validation of the Glasgow-Blatchford Bleeding Score and the Rockall Score in the US setting. Am J Emerg Med. 2012;30:673–9.PubMedCrossRef Chandra S, Hess EP, Agarwal D, Nestler DM, Montori VM, Song LM, et al. External validation of the Glasgow-Blatchford Bleeding Score and the Rockall Score in the US setting. Am J Emerg Med. 2012;30:673–9.PubMedCrossRef
13.
go back to reference Cheng DW, Lu YW, Sekhon HK, Wu BU. A modified Glasgow Blatchford Score improves risk stratification in upper gastrointestinal bleed: a prospective comparison of scoring systems. Aliment Pharmacol Ther. 2012;36(8):782–9.PubMedCrossRef Cheng DW, Lu YW, Sekhon HK, Wu BU. A modified Glasgow Blatchford Score improves risk stratification in upper gastrointestinal bleed: a prospective comparison of scoring systems. Aliment Pharmacol Ther. 2012;36(8):782–9.PubMedCrossRef
14.
go back to reference Blanche MT, Durrheim K, Painter D. Research in practice applied methods for sociel sciences. South Africa: University of Cape Town Press Ltd; 2006. Blanche MT, Durrheim K, Painter D. Research in practice applied methods for sociel sciences. South Africa: University of Cape Town Press Ltd; 2006.
15.
go back to reference Khamaysi I, Gralnek IM. Acute upper gastrointestinal bleeding (UGIB)-Initial evaluation and management. Best Pract Res Clin Gastroenterol. 2013;27:633–8.PubMedCrossRef Khamaysi I, Gralnek IM. Acute upper gastrointestinal bleeding (UGIB)-Initial evaluation and management. Best Pract Res Clin Gastroenterol. 2013;27:633–8.PubMedCrossRef
16.
go back to reference Srirajaskanthan R, Conn R, Bulwer C, Irving P. The Glasgow Blatchford scoring system enables accurate risk stratification of patients with upper gastrointestinal haemorrhage. Int J Clin Practice. 2010;64:868–74.CrossRef Srirajaskanthan R, Conn R, Bulwer C, Irving P. The Glasgow Blatchford scoring system enables accurate risk stratification of patients with upper gastrointestinal haemorrhage. Int J Clin Practice. 2010;64:868–74.CrossRef
17.
go back to reference Subbe CP, Kruger M, Rutherford P, Gemmel L. Validation of modified early warning score in medical admissions. QJM. 2001;94:521–6.PubMedCrossRef Subbe CP, Kruger M, Rutherford P, Gemmel L. Validation of modified early warning score in medical admissions. QJM. 2001;94:521–6.PubMedCrossRef
18.
go back to reference Bryant RV, Kuo P, Williamson K, Yam C, Schoeman MN, Holloway RH, et al. Performance of the Glasgow-Blatchford score in predicting clinical outcomes and intervention in hospitalized patients with upper GI bleeding. Gastrointest Endosc. 2013;78(4):576–83.PubMedCrossRef Bryant RV, Kuo P, Williamson K, Yam C, Schoeman MN, Holloway RH, et al. Performance of the Glasgow-Blatchford score in predicting clinical outcomes and intervention in hospitalized patients with upper GI bleeding. Gastrointest Endosc. 2013;78(4):576–83.PubMedCrossRef
20.
go back to reference Stephens JR, Hare NC, Warshow U, Hamad N, Fellows HJ, Pritchard C, et al. Management of minor upper gastrointestinal haemorrhage in the community using the Glasgow BlatchfordScore. Eur J Gastroenterol Hepatol. 2009;21(12):1340–6.PubMedCrossRef Stephens JR, Hare NC, Warshow U, Hamad N, Fellows HJ, Pritchard C, et al. Management of minor upper gastrointestinal haemorrhage in the community using the Glasgow BlatchfordScore. Eur J Gastroenterol Hepatol. 2009;21(12):1340–6.PubMedCrossRef
21.
go back to reference Stanley AJ, Dalton HR, Blatchford O, Ashley D, Mowat C, Cahill A, et al. Multicentre comparison of the Glasgow Blatchford and Rockall scores in the prediction of clinical end points after upper gastrointestinal haemorrhage. Aliment Pharmacol Ther. 2011;34(4):470–5.PubMedCrossRef Stanley AJ, Dalton HR, Blatchford O, Ashley D, Mowat C, Cahill A, et al. Multicentre comparison of the Glasgow Blatchford and Rockall scores in the prediction of clinical end points after upper gastrointestinal haemorrhage. Aliment Pharmacol Ther. 2011;34(4):470–5.PubMedCrossRef
22.
go back to reference Meltzer AC, Burnett S, Pinchbeck C, Brown AL, Choudhri T, Yadav K, et al. Pre-endoscopic Rockall and Blatchford scores to identify which emergency department patients with suspected gastrointestinal bleed do not need endoscopic hemostasis. J Emerg Med. 2013;44(6):1083–7.PubMedCrossRef Meltzer AC, Burnett S, Pinchbeck C, Brown AL, Choudhri T, Yadav K, et al. Pre-endoscopic Rockall and Blatchford scores to identify which emergency department patients with suspected gastrointestinal bleed do not need endoscopic hemostasis. J Emerg Med. 2013;44(6):1083–7.PubMedCrossRef
23.
go back to reference Chen IC, Hung MS, Chiu TF, Chen JC, Hsiao CT. Risk scoring systems to predict need for clinical intervention for patients with nonvariceal upper gastrointestinal tract bleeding. Am J Emerg Med. 2007;25(7):774–9.PubMedCrossRef Chen IC, Hung MS, Chiu TF, Chen JC, Hsiao CT. Risk scoring systems to predict need for clinical intervention for patients with nonvariceal upper gastrointestinal tract bleeding. Am J Emerg Med. 2007;25(7):774–9.PubMedCrossRef
24.
go back to reference Ali H, Lang E, Barkan A. Emergency department risk stratification in upper gastrointestinal bleeding. CJEM. 2012;14(1):45–9.PubMed Ali H, Lang E, Barkan A. Emergency department risk stratification in upper gastrointestinal bleeding. CJEM. 2012;14(1):45–9.PubMed
25.
go back to reference Dicu D, Pop F, Lonescu D, Dicu T. Comparison of risk scoring systems in predicting clinical outcome at upper gastrointestinal bleeding patients in an emergency unit. Am J Emerg Med. 2013;31(1):94–9.PubMedCrossRef Dicu D, Pop F, Lonescu D, Dicu T. Comparison of risk scoring systems in predicting clinical outcome at upper gastrointestinal bleeding patients in an emergency unit. Am J Emerg Med. 2013;31(1):94–9.PubMedCrossRef
26.
go back to reference Stanley AJ, Ashley D, Dalton HR, Mowat C, Gaya DR, Thompson E, et al. Outpatient management of patients with low-risk upper-gastrointestinal haemorrhage: multicentre validation and prospective evaluation. Lancet. 2009;373:42–7.PubMedCrossRef Stanley AJ, Ashley D, Dalton HR, Mowat C, Gaya DR, Thompson E, et al. Outpatient management of patients with low-risk upper-gastrointestinal haemorrhage: multicentre validation and prospective evaluation. Lancet. 2009;373:42–7.PubMedCrossRef
27.
go back to reference Masaoka T, Suzuki H, Hori S, Aikawa N, Hibi T. Blatchford scoring system is a useful scoring system for detecting patients with upper gastrointestinal bleeding who do not need endoscopic intervention. J Gastroenterol Hepatol. 2007;22:1404–8.PubMedCrossRef Masaoka T, Suzuki H, Hori S, Aikawa N, Hibi T. Blatchford scoring system is a useful scoring system for detecting patients with upper gastrointestinal bleeding who do not need endoscopic intervention. J Gastroenterol Hepatol. 2007;22:1404–8.PubMedCrossRef
Metadata
Title
Validity of modified early warning, Glasgow Blatchford, and pre-endoscopic Rockall scores in predicting prognosis of patients presenting to emergency department with upper gastrointestinal bleeding
Authors
Seyran Bozkurt
Ataman Köse
Engin Deniz Arslan
Semra Erdoğan
Enver Üçbilek
İbrahim Çevik
Cüneyt Ayrık
Orhan Sezgin
Publication date
01-12-2015
Publisher
BioMed Central
DOI
https://doi.org/10.1186/s13049-015-0194-z

Other articles of this Issue 1/2015

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 1/2015 Go to the issue