Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Health and Quality of Life Outcomes
Published in: Health and Quality of Life Outcomes 1/2005

Open Access 01-12-2005 | Research

Validation of a patient-administered questionnaire to measure the activity impairment experienced by women with uncomplicated urinary tract infection: the Activity Impairment Assessment (AIA)

Authors: Diane J Wild, Darren J Clayson, Karen Keating, Kathleen Gondek

Published in: Health and Quality of Life Outcomes | Issue 1/2005

Login to get access

Abstract

Background

To validate a questionnaire to assess the activity impairment associated with uncomplicated urinary tract infection (uUTI).

Methods

The Activity Impairment Assessment (AIA) assesses the amount of time an individual's work or regular activities have been impaired as a result of their UTI. The measure was completed by 276 women with uUTI who had participated in a prospective, open-label, non-comparative multi-centre clinical trial of CIPRO® XR (extended-release ciprofloxacin). Baseline scores on the King's Health Questionnaire (KHQ) and clinical symptom evaluations were collected for validation purposes.

Results

An exploratory factor analysis showed that all items loaded >0.84 on a single component. This uni-dimensional structure was supported by Rasch analysis. The AIA was found to have excellent levels of internal consistency (Cronbach's alpha = 0.93), convergent validity (all rs >.70) and divergent validity (rs = .078). The AIA displayed excellent discriminant validity in relation to clinical evaluations, and was found to be responsive to change across all clinical evaluations.

Conclusion

The unidimensional AIA shows high levels of internal reliability, convergent and divergent validity, discriminant validity and responsiveness. It is an excellent tool for measuring activity impairment in UTI.
Literature
1.
Colgan R, Keating K, Dougouih M: Survey of symptom burden in women with uncomplicated urinary tract infections. Clin Drug Invest 2004, 24: 55–60.CrossRef
2.
Nicolle L: Epidemiology of urinary tract infections. Infect Med 2001, 18: 153–162.
3.
Foxman B: Epidemiology of Urinary Tract Infections: Incidence, Morbidity, and Economic Costs. Dis Mon 2003, 49: 53–70. 10.1016/S0011-5029(03)90000-9PubMedCrossRef
4.
Foxman B, Marsh JV, Gillespie B, Sobel JD: Frequency and Response to Vaginal Symptoms Among White and African American Women: Results of a Random Digit Dialing Survey. J Womens Health 1998, 7: 1167–1174.PubMedCrossRef
5.
Rubin RH, Beam TR Jr, Stamm WE: An Approach to Evaluating Antibacterial Agents in the Treatment of Urinary Tract Infection. Clin Infect Dis 1992, 14: S246-S251.PubMedCrossRef
6.
Brumfitt W, Hamilton-Miller JM, Gillespie WA: The Mysterious 'Urethral Syndrome'. BMJ 303: 719–720.
7.
Ellis AK, Verma S: Quality of Life in Women With Urinary Tract Infections: Is Benign Disease a Misnomer? J Am Board Fam Pract 2000, 13: 392–397.PubMedCrossRef
8.
Malterud K, Baerheim A: Peeing Barbed Wire. Symptom Experiences in Women With Lower Urinary Tract Infection. Scand J Prim Health Care 1999, 17: 49–53. 10.1080/028134399750002683PubMedCrossRef
9.
10.
11.
Anderson TP, Newman E, Dryja R, Price M: Urinary Tract Care: Improvement Through Patient Education. Arch Phys Med Rehabil 1983, 64: 314–316.PubMed
12.
Koopman C, Pelletier K, Murray J, Sharda C, Turpin R, Hackleman P, Gibson P, Holmes D, Taylor B: Stanford Presenteeism Scale: Health Status and Employee Productivity. J Occup Environ Med 2002, 44: 14–20.PubMedCrossRef
13.
Kelleher CJ, Cardozo LD, Khullar V, Salvatore S: A New Questionnaire to Assess the Quality of Life of Urinary Incontinent Women. Br J Obstet Gynaecol 1997, 104: 1374–1379.PubMedCrossRef
14.
Reese PR, Pleil AM, Okano GJ, Kelleher CJ: Multinational Study of Reliability and Validity of the King's Health Questionnaire in Patients With Overactive Bladder. Qual Life Res 2003, 12: 427–442. 10.1023/A:1023422208910PubMedCrossRef
15.
Uemura S, Homma Y: Reliability and Validity of King's Health Questionnaire in Patients With Symptoms of Overactive Bladder With Urge Incontinence in Japan. Neurourol Urodyn 2004, 23: 94–100. 10.1002/nau.10169PubMedCrossRef
16.
Statistical Package for Social Sciences In (SPSS) Version 12.0. Chicago, Illinois; 2004.
17.
Sheridan B: RUMM Item Analysis Package: Rasch Unidimensional Measurement Model. Rasch Measurement Transactions 1998,11(4):599.
18.
Hambleton RK, Jones RW: Comparison of classical test theory and item response theory and their applications to test development. Educational Measurement Issues and Practice 1993, 12: 38–47.CrossRef
19.
Cialdella P, Figon G, Haugh MC, Boissel JP: Prescription Intentions in Relation to Therapeutic Information: a Study of 117 French General Practitioners. Soc Sci Med 1991, 33: 1263–1274. 10.1016/0277-9536(91)90074-MPubMedCrossRef
20.
Nunnally JC, Bernstein IH: Psychometric theory . 3rd edition. New York: McGraw- Hill Series in Psychology; 1978.
21.
Kline P: The Handbook of Psychological Testing. London: Routledge; 1993.
Metadata
Title
Validation of a patient-administered questionnaire to measure the activity impairment experienced by women with uncomplicated urinary tract infection: the Activity Impairment Assessment (AIA)
Authors
Diane J Wild
Darren J Clayson
Karen Keating
Kathleen Gondek
Publication date
01-12-2005
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2005
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/1477-7525-3-42

Other articles of this Issue 1/2005

Health and Quality of Life Outcomes 1/2005 Go to the issue

Research

Modification of the asthma quality of life questionnaire (standardised) for patients 12 years and older

Research

Health-related quality of life and physical well-being among a 63-year-old cohort of women with androgenetic alopecia; a Finnish population-based study

Research

Combination of qualitative and quantitative methods for developing a new Health Related Quality of Life measure for patients with anogenital warts

Research

Differential effect sizes of growth hormone replacement on quality of life, well-being and health status in growth hormone deficient patients: a meta-analysis

Research

Ethnic differential item functioning in the assessment of quality of life in cancer patients

Research

Are decisions using cost-utility analyses robust to choice of SF-36/SF-12 preference-based algorithm?