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Acta Epileptologica
Published in: Acta Epileptologica 1/2024

Open Access 01-12-2024 | Vagus Nerve Stimulation | Review

Research progress on the electrophysiological indicators to predict the efficacy of vagus nerve stimulation for drug-refractory epilepsy

Authors: Guangli Li, Zhenguang Li, Yingting Liu

Published in: Acta Epileptologica | Issue 1/2024

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Abstract

Vagus nerve stimulation (VNS) is an important treatment option for drug-refractory epilepsy (DRE), with well-established efficacy and safety in clinical practice for more than 20 years. However, it is very difficult to find the optimal electrophysiological indicators for the effectiveness of VNS on DRE because the mechanism of action is unknown. In this review, we provide an update of the potential applications of VNS outcomes in patients with drug-resistant epilepsy. Electroencephalographic (EEG) activity, event-related potentials, EEG synchronization levels, magnetoencephalographic, laryngeal muscle evoked potentials, and heart rate variability are potential biomarkers for VNS outcomes in people with DRE.
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Metadata
Title
Research progress on the electrophysiological indicators to predict the efficacy of vagus nerve stimulation for drug-refractory epilepsy
Authors
Guangli Li
Zhenguang Li
Yingting Liu
Publication date
01-12-2024
Publisher
BioMed Central
Published in
Acta Epileptologica / Issue 1/2024
Print ISSN: 2096-9384
Electronic ISSN: 2524-4434
DOI
https://doi.org/10.1186/s42494-023-00147-y

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