Skip to main content
Top
Published in: Hernia 5/2013

Open Access 01-10-2013 | Original Article

Use of antibiotic prophylaxis in elective inguinal hernia repair in adults in London and south-east England: a cross-sectional survey

Authors: A. M. Aiken, J. B. Haddow, N. R. A. Symons, S. Kaptanis, A. C. Katz-Summercorn, D. Debnath, H. Dent, S. Tayeh, V. Kung, S. Clark, J. Gahir, S. Dindyal, S. Farag, A. Lazaridis, C. P. Bretherton, S. Williams, A. Currie, H. West, J. Davies, S. Arora, A. Kheraj, B. M. Stubbs, N. Yassin, S. Mallappa, G. Garrett, S. Hislop, A. Bhangu, Y. Abbey, I. Al-Shoek, U. Ahmad, G. Sharp, A. Memarzadeh, A. Patel, F. Ali, H. Kaderbhai, C. H. Knowles

Published in: Hernia | Issue 5/2013

Login to get access

Abstract

Purpose

Evidence regarding whether or not antibiotic prophylaxis is beneficial in preventing post-operative surgical site infection in adult inguinal hernia repair is conflicting. A recent Cochrane review based on 17 randomised trials did not reach a conclusion on this subject. This study aimed to describe the current practice and determine whether clinical equipoise is prevalent.

Methods

Surgeons in training were recruited to administer the Survey of Hernia Antibiotic Prophylaxis usE survey to consultant-level general surgeons in London and the south-east of England on their practices and beliefs regarding antibiotic prophylaxis in adult elective inguinal hernia repair. Local prophylaxis guidelines for the participating hospital sites were also determined.

Results

The study was conducted at 34 different sites and received completed surveys from 229 out of a possible 245 surgeons, a 93 % response rate. Overall, a large majority of hospital guidelines (22/28) and surgeons’ personal beliefs (192/229, 84 %) supported the use of single-dose pre-operative intravenous antibiotic prophylaxis in inguinal hernia repair, although there was considerable variation in the regimens in use. The most widely used regimen was intravenous co-amoxiclav (1.2 g). Less than half of surgeons were adherent to their own hospital antibiotic guidelines for this procedure, although many incorrectly believed that they were following these.

Conclusion

In the south-east of England, there is a strong majority of surgical opinion in favour of the use of antibiotic prophylaxis in this procedure. It is therefore likely to be extremely difficult to conduct further randomised studies in the UK to support or refute the effectiveness of prophylaxis in this commonly performed procedure.
Appendix
Available only for authorised users
Literature
1.
3.
go back to reference Bowater RJ, Stirling SA, Lilford RJ (2009) Is antibiotic prophylaxis in surgery a generally effective intervention? Testing a generic hypothesis over a set of meta-analyses. Ann Surg 249(4):551–556PubMedCrossRef Bowater RJ, Stirling SA, Lilford RJ (2009) Is antibiotic prophylaxis in surgery a generally effective intervention? Testing a generic hypothesis over a set of meta-analyses. Ann Surg 249(4):551–556PubMedCrossRef
4.
go back to reference Bratzler DW, Houck PM (2004) Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project. Clin Infect Dis 38(12):1706–1715PubMedCrossRef Bratzler DW, Houck PM (2004) Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project. Clin Infect Dis 38(12):1706–1715PubMedCrossRef
5.
go back to reference Hedrick TL, Sawyer RG (2012) The end of postoperative antimicrobial prophylaxis? Lancet Infect Dis 12(5):357–358PubMedCrossRef Hedrick TL, Sawyer RG (2012) The end of postoperative antimicrobial prophylaxis? Lancet Infect Dis 12(5):357–358PubMedCrossRef
6.
go back to reference Sanchez-Manuel FJ, Lozano-Garcia J, Seco-Gil JL (2012) Antibiotic prophylaxis for hernia repair. Cochrane Database Syst Rev 2:003769 Sanchez-Manuel FJ, Lozano-Garcia J, Seco-Gil JL (2012) Antibiotic prophylaxis for hernia repair. Cochrane Database Syst Rev 2:003769
7.
go back to reference Li JF et al (2012) Meta-analysis of the effectiveness of prophylactic antibiotics in the prevention of postoperative complications after tension-free hernioplasty. Can J Surg 55(1):27–32PubMed Li JF et al (2012) Meta-analysis of the effectiveness of prophylactic antibiotics in the prevention of postoperative complications after tension-free hernioplasty. Can J Surg 55(1):27–32PubMed
8.
go back to reference Ergul Z et al (2012) Prophylactic antibiotic use in elective inguinal hernioplasty in a trauma center. Hernia 16(2):145–151PubMedCrossRef Ergul Z et al (2012) Prophylactic antibiotic use in elective inguinal hernioplasty in a trauma center. Hernia 16(2):145–151PubMedCrossRef
11.
go back to reference Simons MP et al (2009) European Hernia Society guidelines on the treatment of inguinal hernia in adult patients. Hernia 13(4):343–403PubMedCrossRef Simons MP et al (2009) European Hernia Society guidelines on the treatment of inguinal hernia in adult patients. Hernia 13(4):343–403PubMedCrossRef
12.
go back to reference Latthe PM et al (2005) Measurement of beliefs about effectiveness of laparoscopic uterosacral nerve ablation. BJOG 112(2):243–246PubMedCrossRef Latthe PM et al (2005) Measurement of beliefs about effectiveness of laparoscopic uterosacral nerve ablation. BJOG 112(2):243–246PubMedCrossRef
13.
go back to reference von Elm E et al (2007) The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet 370(9596):1453–1457CrossRef von Elm E et al (2007) The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet 370(9596):1453–1457CrossRef
14.
go back to reference McHugh SM et al (2011) The role of topical antibiotics used as prophylaxis in surgical site infection prevention. J Antimicrob Chemother 66(4):693–701PubMedCrossRef McHugh SM et al (2011) The role of topical antibiotics used as prophylaxis in surgical site infection prevention. J Antimicrob Chemother 66(4):693–701PubMedCrossRef
15.
go back to reference Codina C et al (1999) Perioperative antibiotic prophylaxis in Spanish hospitals: results of a questionnaire survey. Hospital Pharmacy Antimicrobial Prophylaxis Study Group. Infect Control Hosp Epidemiol 20(6):436–439PubMedCrossRef Codina C et al (1999) Perioperative antibiotic prophylaxis in Spanish hospitals: results of a questionnaire survey. Hospital Pharmacy Antimicrobial Prophylaxis Study Group. Infect Control Hosp Epidemiol 20(6):436–439PubMedCrossRef
16.
go back to reference Heineck I, Ferreira MB, Schenkel EP (1999) Prescribing practice for antibiotic prophylaxis for 3 commonly performed surgeries in a teaching hospital in Brazil. Am J Infect Control 27(3):296–300PubMedCrossRef Heineck I, Ferreira MB, Schenkel EP (1999) Prescribing practice for antibiotic prophylaxis for 3 commonly performed surgeries in a teaching hospital in Brazil. Am J Infect Control 27(3):296–300PubMedCrossRef
17.
go back to reference Pleat JM et al (2004) Prospective survey of factors affecting risk discussion during consent in a surgical specialty. Br J Surg 91(10):1377–1380PubMedCrossRef Pleat JM et al (2004) Prospective survey of factors affecting risk discussion during consent in a surgical specialty. Br J Surg 91(10):1377–1380PubMedCrossRef
18.
go back to reference Callaghan CJ et al (2002) Breast reconstruction in the United Kingdom and Ireland. Br J Surg 89(3):335–340PubMedCrossRef Callaghan CJ et al (2002) Breast reconstruction in the United Kingdom and Ireland. Br J Surg 89(3):335–340PubMedCrossRef
19.
go back to reference Johnson N, Lilford RJ, Brazier W (1991) At what level of collective equipoise does a clinical trial become ethical? J Med Ethics 17(1):30–34PubMedCrossRef Johnson N, Lilford RJ, Brazier W (1991) At what level of collective equipoise does a clinical trial become ethical? J Med Ethics 17(1):30–34PubMedCrossRef
Metadata
Title
Use of antibiotic prophylaxis in elective inguinal hernia repair in adults in London and south-east England: a cross-sectional survey
Authors
A. M. Aiken
J. B. Haddow
N. R. A. Symons
S. Kaptanis
A. C. Katz-Summercorn
D. Debnath
H. Dent
S. Tayeh
V. Kung
S. Clark
J. Gahir
S. Dindyal
S. Farag
A. Lazaridis
C. P. Bretherton
S. Williams
A. Currie
H. West
J. Davies
S. Arora
A. Kheraj
B. M. Stubbs
N. Yassin
S. Mallappa
G. Garrett
S. Hislop
A. Bhangu
Y. Abbey
I. Al-Shoek
U. Ahmad
G. Sharp
A. Memarzadeh
A. Patel
F. Ali
H. Kaderbhai
C. H. Knowles
Publication date
01-10-2013
Publisher
Springer Paris
Published in
Hernia / Issue 5/2013
Print ISSN: 1265-4906
Electronic ISSN: 1248-9204
DOI
https://doi.org/10.1007/s10029-013-1061-3

Other articles of this Issue 5/2013

Hernia 5/2013 Go to the issue