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BMC Medical Imaging
Published in: BMC Medical Imaging 1/2024

Open Access 01-12-2024 | Urothelial Cancer | Research

Application of contrast-enhanced ultrasound in diagnosis and grading of bladder urothelial carcinoma

Authors: Hui-ping Zhang, Rong-xi Liang, Xue-ying Lin, En-sheng Xue, Qin Ye, Yi-fan Zhu

Published in: BMC Medical Imaging | Issue 1/2024

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Abstract

Purpose

To explore the application of contrast-enhanced ultrasound (CEUS) for the diagnosis and grading of bladder urothelial carcinoma (BUC).

Methods

The results of a two-dimensional ultrasound, color Doppler ultrasound and CEUS, were analyzed in 173 bladder lesion cases. The ultrasound and surgical pathology results were compared, and their diagnostic efficacy was analyzed.

Results

There were statistically significant differences between BUC and benign lesions in terms of color blood flow distribution intensity and CEUS enhancement intensity (both P < 0.05). The area under the time-intensity curve (AUC), rising slope, and peak intensity of BUC were significantly higher than those of benign lesions (all P < 0.05). The H/T (height H / basal width T)value of 0.63 was the critical value for distinguishing high- and low-grade BUC, had a diagnostic sensitivity of 80.0% and a specificity of 60.0%.

Conclusion

The combination of CEUS and TIC can help improve the diagnostic accuracy of BUC. There is a statistically significant difference between high- and low-grade BUC in contrast enhancement intensity (P < 0.05); The decrease of H/T value indicates the possible increase of the BUC grade.
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Metadata
Title
Application of contrast-enhanced ultrasound in diagnosis and grading of bladder urothelial carcinoma
Authors
Hui-ping Zhang
Rong-xi Liang
Xue-ying Lin
En-sheng Xue
Qin Ye
Yi-fan Zhu
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Medical Imaging / Issue 1/2024
Electronic ISSN: 1471-2342
DOI
https://doi.org/10.1186/s12880-024-01199-3

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