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Published in: International Urogynecology Journal 12/2008

01-12-2008 | Original Article

Urodynamic characterization of obese women with urinary incontinence undergoing a weight loss program: the Program to Reduce Incontinence by Diet and Exercise (PRIDE) trial

Authors: Holly E. Richter, Jennifer M. Creasman, Deborah L. Myers, Thomas L. Wheeler, Kathryn L. Burgio, Leslee L. Subak, for the Program to Reduce Incontinence by Diet and Exercise (PRIDE) Research Group

Published in: International Urogynecology Journal | Issue 12/2008

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Abstract

The purpose of this study was to describe urodynamic characteristics of overweight or obese women with urinary incontinence and explore the relationship between urodynamic parameters, body mass index (BMI), and abdominal circumference (AC). One hundred ten women underwent a standardized cough stress test and urodynamic study. Eighty-six percent of women had urodynamic stress incontinence and 15% detrusor overactivity. Intra-abdominal pressure (Pabd) at maximum cystometric capacity (MCC) increased 0.4 cm H2O per kg/m2 unit of BMI (95% confidence interval [CI] = 0.0,0.7, p = 0.04) and 0.4 cm H2O per 2 cm increase in AC (CI = 0.2, 0.7, p < 0.01). Intravesical pressure (Pves) at MCC increased 0.4 cm H2O per 2 cm increase in AC (CI = 0.0, 0.8, p = 0.05) but was not associated with BMI (p = 0.18). BMI and AC had a stronger association with Pabd than with Pves, suggesting a possible mechanism for the association between obesity and urinary incontinence.
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Metadata
Title
Urodynamic characterization of obese women with urinary incontinence undergoing a weight loss program: the Program to Reduce Incontinence by Diet and Exercise (PRIDE) trial
Authors
Holly E. Richter
Jennifer M. Creasman
Deborah L. Myers
Thomas L. Wheeler
Kathryn L. Burgio
Leslee L. Subak
for the Program to Reduce Incontinence by Diet and Exercise (PRIDE) Research Group
Publication date
01-12-2008
Publisher
Springer-Verlag
Published in
International Urogynecology Journal / Issue 12/2008
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-008-0694-8

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