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Published in: BMC Geriatrics 1/2022

Open Access 01-12-2022 | Urinary Incontinence | Research

Detecting disabilities in everyday life: evidence from a geriatric assessment

Authors: Cornelius Dzien, Petra Unterberger, Paul Hofmarcher, Hannes Winner, Monika Lechleitner

Published in: BMC Geriatrics | Issue 1/2022

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Abstract

Background

The activities of daily living (ADL) score is a widely used index to establish the degree of independence from any help in everyday life situations. Measuring ADL accurately is time-consuming and costly. This paper presents a framework to approximate ADL via variables usually collected in comprehensive geriatric assessments. We show that the selected variables serve as good indicators in explaining the physical disabilities of older patients.

Methods

Our sample included information from a geriatric assessment of 326 patients aged between 64 and 99 years in a hospital in Tyrol, Austria. In addition to ADL, 23 variables reflecting the physical and mental status of these patients were recorded during the assessment. We performed least absolute shrinkage and selection operator (LASSO) to determine which of these variables had the highest impact on explaining ADL. Then, we used receiver operating characteristic (ROC) analysis and logistic regression techniques to validate our model performance. Finally, we calculated cut-off points for each of the selected variables to show the values at which ADL fall below a certain threshold.

Results

Mobility, urinary incontinence, nutritional status and cognitive function were most closely related to ADL and, therefore, to geriatric patients’ functional limitations. Jointly, the selected variables were able to detect neediness with high accuracy (area under the ROC curve (AUC) = 0.89 and 0.91, respectively). If a patient had a limitation in one of these variables, the probability of everyday life disability increased with a statistically significant factor between 2.4 (nutritional status, 95%-CI 1.5–3.9) and 15.1 (urinary incontinence, 95%-CI 3.6–63.4).

Conclusions

Our study highlights the most important impairments of everyday life to facilitate more efficient use of clinical resources, which in turn allows for more targeted treatment of geriatric patients. At the patient level, our approach enables early detection of functional limitations and timely indications of a possible need for assistance in everyday life.
Appendix
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Footnotes
1
For the sake of brevity, we henceforth refer to these variables as “explanatory variables” or “geriatric covariates”.
 
Literature
1.
go back to reference Stuck AE, Siu AL, Wieland GD, Rubenstein L, Adams J. Comprehensive geriatric assessment: A meta-analysis of controlled trials. Lancet. 1993; 342(8878):1032–36.PubMedCrossRef Stuck AE, Siu AL, Wieland GD, Rubenstein L, Adams J. Comprehensive geriatric assessment: A meta-analysis of controlled trials. Lancet. 1993; 342(8878):1032–36.PubMedCrossRef
2.
go back to reference Pepersack T. Minimum geriatric screening tools to detect common geriatric problems. J Nutr Health Aging. 2008; 12(5):348–52.PubMedCrossRef Pepersack T. Minimum geriatric screening tools to detect common geriatric problems. J Nutr Health Aging. 2008; 12(5):348–52.PubMedCrossRef
3.
go back to reference Elsawy B, Higgins KE. The geriatric assessment. Am Fam Physician. 2011; 83(1):48–56.PubMed Elsawy B, Higgins KE. The geriatric assessment. Am Fam Physician. 2011; 83(1):48–56.PubMed
4.
go back to reference Wojtusiak J, Asadzadehzanjani N, Levy C, Alemi F, Williams AE. Computational Barthel index: An automated tool for assessing and predicting activities of daily living among nursing home patients. BMC Med Inform Decis Making. 2021; 21(1):1–15.CrossRef Wojtusiak J, Asadzadehzanjani N, Levy C, Alemi F, Williams AE. Computational Barthel index: An automated tool for assessing and predicting activities of daily living among nursing home patients. BMC Med Inform Decis Making. 2021; 21(1):1–15.CrossRef
5.
go back to reference Hong Y-J, Kim I-J, Ahn SC, Kim H-G. Activity recognition using wearable sensors for elder care. In: 2008 Second International Conference on Future Generation Communication and Networking, vol. 2. Hainan Island: IEEE; 2008. p. 302–05. Hong Y-J, Kim I-J, Ahn SC, Kim H-G. Activity recognition using wearable sensors for elder care. In: 2008 Second International Conference on Future Generation Communication and Networking, vol. 2. Hainan Island: IEEE; 2008. p. 302–05.
6.
go back to reference Liu J, Sohn J, Kim S. Classification of daily activities for the elderly using wearable sensors. J Healthc Eng. 2017; 2017:8934816. Liu J, Sohn J, Kim S. Classification of daily activities for the elderly using wearable sensors. J Healthc Eng. 2017; 2017:8934816.
7.
go back to reference Guralnik JM, Ferrucci L, Pieper CF, Leveille SG, Markides KS, Ostir GV, Studenski S, Berkman LF, Wallace RB. Lower extremity function and subsequent disability: Consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery. J Gerontol A Biol Sci Med Sci. 2000; 55(4):221–31.CrossRef Guralnik JM, Ferrucci L, Pieper CF, Leveille SG, Markides KS, Ostir GV, Studenski S, Berkman LF, Wallace RB. Lower extremity function and subsequent disability: Consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery. J Gerontol A Biol Sci Med Sci. 2000; 55(4):221–31.CrossRef
8.
go back to reference Prasitsiriphon O, Weber D. Objective physical measures and their association with subjective functional limitations in a representative study population of older Thais. BMC Geriatr. 2019; 19(1):1–12.CrossRef Prasitsiriphon O, Weber D. Objective physical measures and their association with subjective functional limitations in a representative study population of older Thais. BMC Geriatr. 2019; 19(1):1–12.CrossRef
9.
go back to reference Jonkman NH, Colpo M, Klenk J, Todd C, Hoekstra T, Del Panta V, Rapp K, Van Schoor NM, Bandinelli S, Heymans MW, et al. Development of a clinical prediction model for the onset of functional decline in people aged 65–75 years: Pooled analysis of four european cohort studies. BMC Geriatr. 2019; 19(1):1–12.CrossRef Jonkman NH, Colpo M, Klenk J, Todd C, Hoekstra T, Del Panta V, Rapp K, Van Schoor NM, Bandinelli S, Heymans MW, et al. Development of a clinical prediction model for the onset of functional decline in people aged 65–75 years: Pooled analysis of four european cohort studies. BMC Geriatr. 2019; 19(1):1–12.CrossRef
10.
go back to reference Collin C, Wade D, Davies S, Horne V. The Barthel ADL index: A reliability study. Int Disabil Stud. 1988; 10(2):61–63.PubMedCrossRef Collin C, Wade D, Davies S, Horne V. The Barthel ADL index: A reliability study. Int Disabil Stud. 1988; 10(2):61–63.PubMedCrossRef
11.
go back to reference Mahoney F, Barthel DW. Functional evaluation: The Barthel index. Maryland State Med J. 1965; 14(2):61–65. Mahoney F, Barthel DW. Functional evaluation: The Barthel index. Maryland State Med J. 1965; 14(2):61–65.
12.
go back to reference Gobbens RJ, van Assen MA. The prediction of ADL and IADL disability using six physical indicators of frailty: A longitudinal study in the Netherlands. Curr Gerontol Geriatr Res. 2014; 2014:358137.PubMedPubMedCentral Gobbens RJ, van Assen MA. The prediction of ADL and IADL disability using six physical indicators of frailty: A longitudinal study in the Netherlands. Curr Gerontol Geriatr Res. 2014; 2014:358137.PubMedPubMedCentral
14.
go back to reference Sinoff G, Ore L. The Barthel activities of daily living index: Self-reporting versus actual performance in the old-old (≥ 75 years). J Am Geriatr Soc. 1997; 45(7):832–36.PubMedCrossRef Sinoff G, Ore L. The Barthel activities of daily living index: Self-reporting versus actual performance in the old-old (≥ 75 years). J Am Geriatr Soc. 1997; 45(7):832–36.PubMedCrossRef
15.
go back to reference Hartigan I. A comparative review of the Katz ADL and the Barthel index in assessing the activities of daily living of older people. Int J Older People Nursing. 2007; 2(3):204–12.CrossRef Hartigan I. A comparative review of the Katz ADL and the Barthel index in assessing the activities of daily living of older people. Int J Older People Nursing. 2007; 2(3):204–12.CrossRef
16.
go back to reference Deppermann K-M, Friedrich C, Herth F, Huber RM. Geriatrische assessments und diagnostik beim älteren patienten. Oncol Res Treat. 2008; 31(Suppl. 3):6–14. Deppermann K-M, Friedrich C, Herth F, Huber RM. Geriatrische assessments und diagnostik beim älteren patienten. Oncol Res Treat. 2008; 31(Suppl. 3):6–14.
17.
go back to reference Tinetti ME. Performance-oriented assessment of mobility problems in elderly patients. J Am Geriatr Soc. 1986; 34(2):119–26.PubMedCrossRef Tinetti ME. Performance-oriented assessment of mobility problems in elderly patients. J Am Geriatr Soc. 1986; 34(2):119–26.PubMedCrossRef
19.
go back to reference Podsiadlo D, Richardson S. The timed "Up & Go": A test of basic functional mobility for frail elderly persons. J Am Geriatr Soc. 1991; 39(2):142–48.PubMedCrossRef Podsiadlo D, Richardson S. The timed "Up & Go": A test of basic functional mobility for frail elderly persons. J Am Geriatr Soc. 1991; 39(2):142–48.PubMedCrossRef
20.
go back to reference Choquette S, Bouchard D, Doyon C, Sénéchal M, Brochu M, Dionne IJ. Relative strength as a determinant of mobility in elders 67–84 years of age. A nuage study: Nutrition as a determinant of successful aging. J Nutr Health Aging. 2010; 14(3):190–95.PubMedCrossRef Choquette S, Bouchard D, Doyon C, Sénéchal M, Brochu M, Dionne IJ. Relative strength as a determinant of mobility in elders 67–84 years of age. A nuage study: Nutrition as a determinant of successful aging. J Nutr Health Aging. 2010; 14(3):190–95.PubMedCrossRef
21.
go back to reference Sommeregger U, Dovjak P, Fasching P, et al. Österreichisches geriatrisches Basisassessment. Österr Ges Geriatr Geronotologie. 2011; 19:1070. Sommeregger U, Dovjak P, Fasching P, et al. Österreichisches geriatrisches Basisassessment. Österr Ges Geriatr Geronotologie. 2011; 19:1070.
22.
go back to reference PHILLIPS P. Grip strength, mental performance and nutritional status as indicators of mortality risk among female geriatric patients. Age Ageing. 1986; 15(1):53–56.PubMedCrossRef PHILLIPS P. Grip strength, mental performance and nutritional status as indicators of mortality risk among female geriatric patients. Age Ageing. 1986; 15(1):53–56.PubMedCrossRef
23.
go back to reference Folstein MF, Folstein SE, McHugh PR. “Mini-Mental State”: A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12(3):189–98.PubMedCrossRef Folstein MF, Folstein SE, McHugh PR. “Mini-Mental State”: A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12(3):189–98.PubMedCrossRef
24.
go back to reference Watson YI, Arfken CL, Birge SJ. Clock completion: An objective screening test for dementia. J Am Geriatr Soc. 1993; 41(11):1235–40.PubMedCrossRef Watson YI, Arfken CL, Birge SJ. Clock completion: An objective screening test for dementia. J Am Geriatr Soc. 1993; 41(11):1235–40.PubMedCrossRef
25.
go back to reference Nikolaus T, Bach M, Oster P, Schlierf G. The timed test of money counting: A simple method of recognizing geriatric patients at risk for increased health care. Aging Clin Exp Res. 1995; 7(3):179–83.CrossRef Nikolaus T, Bach M, Oster P, Schlierf G. The timed test of money counting: A simple method of recognizing geriatric patients at risk for increased health care. Aging Clin Exp Res. 1995; 7(3):179–83.CrossRef
26.
go back to reference Guigoz Y, Vellas B, Garry PJ. Assessing the nutritional status of the elderly: The Mini Nutritional Assessment as part of the geriatric evaluation. Nutr Rev. 1996; 54(1):59.CrossRef Guigoz Y, Vellas B, Garry PJ. Assessing the nutritional status of the elderly: The Mini Nutritional Assessment as part of the geriatric evaluation. Nutr Rev. 1996; 54(1):59.CrossRef
27.
go back to reference Burns R, Nichols L, Calkins E, Blackwell S, Pragay D. Nutritional assessment of community-living well elderly. J Am Geriatr Soc. 1986; 34(11):781–86.PubMedCrossRef Burns R, Nichols L, Calkins E, Blackwell S, Pragay D. Nutritional assessment of community-living well elderly. J Am Geriatr Soc. 1986; 34(11):781–86.PubMedCrossRef
28.
go back to reference Schutz Y, Kyle U, Pichard C. Fat-free mass index and fat mass index percentiles in Caucasians aged 18–98 y. Int J Obes. 2002; 26(7):953–60.CrossRef Schutz Y, Kyle U, Pichard C. Fat-free mass index and fat mass index percentiles in Caucasians aged 18–98 y. Int J Obes. 2002; 26(7):953–60.CrossRef
29.
go back to reference Brown JS, Bradley CS, Subak LL, Richter HE, Kraus SR, Brubaker L, Lin F, Vittinghoff E, Grady D. The sensitivity and specificity of a simple test to distinguish between urge and stress urinary incontinence. Ann Intern Med. 2006; 144(10):715–23.PubMedPubMedCentralCrossRef Brown JS, Bradley CS, Subak LL, Richter HE, Kraus SR, Brubaker L, Lin F, Vittinghoff E, Grady D. The sensitivity and specificity of a simple test to distinguish between urge and stress urinary incontinence. Ann Intern Med. 2006; 144(10):715–23.PubMedPubMedCentralCrossRef
30.
go back to reference Carabellese C, Appollonio I, Rozzini R, Bianchetti A, Frisoni GB, Frattola L, Trabucchi M. Sensory impairment and quality of life in a community elderly population. J Am Geriatr Soc. 1993; 41(4):401–07.PubMedCrossRef Carabellese C, Appollonio I, Rozzini R, Bianchetti A, Frisoni GB, Frattola L, Trabucchi M. Sensory impairment and quality of life in a community elderly population. J Am Geriatr Soc. 1993; 41(4):401–07.PubMedCrossRef
31.
go back to reference Chapman CR, Casey K, Dubner R, Foley K, Gracely R, Reading A. Pain measurement: An overview. Pain. 1985; 22(1):1–31.PubMedCrossRef Chapman CR, Casey K, Dubner R, Foley K, Gracely R, Reading A. Pain measurement: An overview. Pain. 1985; 22(1):1–31.PubMedCrossRef
32.
go back to reference Sheikh JI, Yesavage JA. Geriatric Depression Scale (GDS): Recent evidence and development of a shorter version. Clin Gerontol J Aging Ment Health. 1986; 5(1–2):165–73. Sheikh JI, Yesavage JA. Geriatric Depression Scale (GDS): Recent evidence and development of a shorter version. Clin Gerontol J Aging Ment Health. 1986; 5(1–2):165–73.
33.
go back to reference Nikolaus T, Bach M, Oster P, Schlierf G. Prospective value of self-report and performance-based tests of functional status for 18-month outcomes in elderly patients. Aging Clin Exp Res. 1996; 8(4):271–76.CrossRef Nikolaus T, Bach M, Oster P, Schlierf G. Prospective value of self-report and performance-based tests of functional status for 18-month outcomes in elderly patients. Aging Clin Exp Res. 1996; 8(4):271–76.CrossRef
34.
go back to reference Bahat G, Tufan A, Tufan F, Kilic C, Akpinar TS, Kose M, Erten N, Karan MA, Cruz-Jentoft AJ. Cut-off points to identify sarcopenia according to european working group on sarcopenia in older people (EWGSOP) definition. Clin Nutr. 2016; 35(6):1557–63.PubMedCrossRef Bahat G, Tufan A, Tufan F, Kilic C, Akpinar TS, Kose M, Erten N, Karan MA, Cruz-Jentoft AJ. Cut-off points to identify sarcopenia according to european working group on sarcopenia in older people (EWGSOP) definition. Clin Nutr. 2016; 35(6):1557–63.PubMedCrossRef
35.
go back to reference Tibshirani R. The LASSO method for variable selection in the Cox model. Stat Med. 1997;16(4):385–95.PubMedCrossRef Tibshirani R. The LASSO method for variable selection in the Cox model. Stat Med. 1997;16(4):385–95.PubMedCrossRef
36.
go back to reference Friedman J, Hastie T, Tibshirani R, Narasimhan B. Package ‘glmnet’. CRAN R Repositary. 2021. Friedman J, Hastie T, Tibshirani R, Narasimhan B. Package ‘glmnet’. CRAN R Repositary. 2021.
37.
go back to reference Zou KH, Yu C-R, Liu K, Carlsson MO, Cabrera J. Optimal thresholds by maximizing or minimizing various metrics via ROC-type analysis. Acad Radiol. 2013; 20(7):807–15.PubMedCrossRef Zou KH, Yu C-R, Liu K, Carlsson MO, Cabrera J. Optimal thresholds by maximizing or minimizing various metrics via ROC-type analysis. Acad Radiol. 2013; 20(7):807–15.PubMedCrossRef
38.
go back to reference Unal I. Defining an optimal cut-point value in ROC analysis: An alternative approach. Comput Math Meth Med. 2017;2017:1–14.CrossRef Unal I. Defining an optimal cut-point value in ROC analysis: An alternative approach. Comput Math Meth Med. 2017;2017:1–14.CrossRef
40.
go back to reference Perkins NJ, Schisterman EF. The Youden index and the optimal cut-point corrected for measurement error. Biom J J Math Meth Biosci. 2005; 47(4):428–41. Perkins NJ, Schisterman EF. The Youden index and the optimal cut-point corrected for measurement error. Biom J J Math Meth Biosci. 2005; 47(4):428–41.
41.
go back to reference Greiner M, Pfeiffer D, Smith R. Principles and practical application of the receiver-operating characteristic analysis for diagnostic tests. Prev Vet Med. 2000; 45(1-2):23–41.PubMedCrossRef Greiner M, Pfeiffer D, Smith R. Principles and practical application of the receiver-operating characteristic analysis for diagnostic tests. Prev Vet Med. 2000; 45(1-2):23–41.PubMedCrossRef
42.
go back to reference R Core Team. R: A language and environment for statistical computing. 2021. R Foundation for Statistical Computing. R Core Team. R: A language and environment for statistical computing. 2021. R Foundation for Statistical Computing.
43.
44.
go back to reference Khan MRA, Brandenburger T. ROCit: Performance assessment of binary classifier with visualization. 2020. R Package Version 2.1.1. Khan MRA, Brandenburger T. ROCit: Performance assessment of binary classifier with visualization. 2020. R Package Version 2.1.1.
46.
go back to reference Sallinen J, Stenholm S, Rantanen T, Heliövaara M, Sainio P, Koskinen S. Hand-grip strength cut points to screen older persons at risk for mobility limitation. J Am Geriatr Soc. 2010;58(9):1721–26.PubMedPubMedCentralCrossRef Sallinen J, Stenholm S, Rantanen T, Heliövaara M, Sainio P, Koskinen S. Hand-grip strength cut points to screen older persons at risk for mobility limitation. J Am Geriatr Soc. 2010;58(9):1721–26.PubMedPubMedCentralCrossRef
47.
go back to reference Galasko D, Klauber MR, Hofstetter CR, Salmon DP, Lasker B, Thal LJ. The Mini-Mental State Examination in the early diagnosis of Alzheimer’s disease. Arch Neurol. 1990; 47(1):49–52.PubMedCrossRef Galasko D, Klauber MR, Hofstetter CR, Salmon DP, Lasker B, Thal LJ. The Mini-Mental State Examination in the early diagnosis of Alzheimer’s disease. Arch Neurol. 1990; 47(1):49–52.PubMedCrossRef
48.
go back to reference McDowell I, Kristjansson B, Hill G, Hebert R. Community screening for dementia: The Mini Mental State Exam (MMSE) and Modified Mini-Mental State Exam (3MS) compared. J Clin Epidemiol. 1997; 50(4):377–83.PubMedCrossRef McDowell I, Kristjansson B, Hill G, Hebert R. Community screening for dementia: The Mini Mental State Exam (MMSE) and Modified Mini-Mental State Exam (3MS) compared. J Clin Epidemiol. 1997; 50(4):377–83.PubMedCrossRef
49.
go back to reference Trzepacz PT, Hochstetler H, Wang S, Walker B, Saykin AJ. Relationship between the montreal cognitive assessment and Mini-Mental State Examination for assessment of mild cognitive impairment in older adults. BMC Geriatr. 2015; 15(1):1–9.CrossRef Trzepacz PT, Hochstetler H, Wang S, Walker B, Saykin AJ. Relationship between the montreal cognitive assessment and Mini-Mental State Examination for assessment of mild cognitive impairment in older adults. BMC Geriatr. 2015; 15(1):1–9.CrossRef
50.
go back to reference Perneczky R, Wagenpfeil S, Komossa K, Grimmer T, Diehl J, Kurz A. Mapping scores onto stages: Mini-Mental State Examination and clinical dementia rating. Am J Geriatr Psychiatr. 2006; 14(2):139–44.CrossRef Perneczky R, Wagenpfeil S, Komossa K, Grimmer T, Diehl J, Kurz A. Mapping scores onto stages: Mini-Mental State Examination and clinical dementia rating. Am J Geriatr Psychiatr. 2006; 14(2):139–44.CrossRef
Metadata
Title
Detecting disabilities in everyday life: evidence from a geriatric assessment
Authors
Cornelius Dzien
Petra Unterberger
Paul Hofmarcher
Hannes Winner
Monika Lechleitner
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Geriatrics / Issue 1/2022
Electronic ISSN: 1471-2318
DOI
https://doi.org/10.1186/s12877-022-03368-x

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