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29-12-2022 | Ureterocutaneostomy | Original Article

Comparison of minimally invasive versus open pelvic organ-preserving radical cystectomy in female patients with bladder cancer: a multicenter propensity score matching analysis

Authors: Wenlong Zhong, Jibiao Li, Libo Liu, Peng Hong, Sida Cheng, Kun Xia, Wang He, Han Hao, Lulin Ma, Xuesong Li, Liqun Zhou, Tianxin Lin, Jian Huang

Published in: World Journal of Urology | Issue 2/2023

Abstract

Purpose

To compare the perioperative and oncologic outcomes between minimally invasive pelvic organ-preserving radical cystectomy (MIPOPRC) and open pelvic organ-preserving radical cystectomy (open POPRC) among female patients with bladder cancer (BCa).

Methods

We identified female patients who underwent POPRC for BCa at three centers between January 2006 and April 2018. Female patients who underwent open POPRC were matched with those who underwent MIPOPRC using 1:1 propensity score (PS) matching. The patient demographics and perioperative and oncologic outcomes were evaluated for the comparison between MIPOPRC and open POPRC.

Results

Among the 158 patients enrolled, 83 patients underwent MIPOPRC, and 75 underwent open POPRC. A total of 60 MIPOPRC and 60 open POPRC patients were matched successfully. The cancer-specific survival (CSS) and recurrence-free survival (RFS) did not differ significantly in the propensity score-weighted cohort (p = 0.297 and p = 0.600, respectively). Subgroup analysis by age and pathologic stage in the matched cohort revealed that CSS and RFS were with no differences among all subgroups. Moreover, multivariable Cox regression analyses showed that the surgical approach (MIPOPRC vs open POPRC) was not a predictor of CSS (p = 0.250).

Conclusion

MIPOPRC was non-inferior to open POPRC in terms of oncologic outcomes among female patients. MIPOPRC could be technically feasible in selected female patients with BCa.

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Title: Comparison of minimally invasive versus open pelvic organ-preserving radical cystectomy in female patients with bladder cancer: a multicenter propensity score matching analysis
Authors: Wenlong Zhong
Jibiao Li
Libo Liu
Peng Hong
Sida Cheng
Kun Xia
Wang He
Han Hao
Lulin Ma
Xuesong Li
Liqun Zhou
Tianxin Lin
Jian Huang
Publication date: 29-12-2022
Publisher: Springer Berlin Heidelberg
Keywords: Ureterocutaneostomy
Cystectomy
Minimally Invasive Surgery
Published in: World Journal of Urology / Issue 2/2023
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-022-04232-8

2024 ASCO Annual Meeting

Springer Medicine

Comparison of minimally invasive versus open pelvic organ-preserving radical cystectomy in female patients with bladder cancer: a multicenter propensity score matching analysis

Abstract

Purpose

Methods

Results

Conclusion

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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