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Indian Journal of Hematology and Blood Transfusion

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01-09-2014 | Case Report

Unilateral Renal Vein Thrombosis and Adrenal Hemorrhage in A Newborn with Homozygous Factor V Leiden and Heterozygous Of MTHFR-677T, MTHFR-1298C Gene Mutations

Authors: Gonca Sandal, Elvan Arıkan, Ayça Esra Kuybulu, Ahmet Rifat Ormecı

Published in: Indian Journal of Hematology and Blood Transfusion | Special Issue 1/2014

Abstract

Renal vein thrombosis (RVT) occurs as an acute and life-threatening event in neonates. RVT is the most common non–catheter-related thrombosis in infancy and occurs primarily in the newborn period. Non-catheter-related abdominal thrombosis on neonates has a higher incidence of genetic prothrombotic risk factors. RVT and adrenal hemorrhage can both be encountered in the neonatal period and they may occur at the same time (Bokenkamp et al., Eur J Pediatr 159:44–8, 2000; Lau et al. Pediatrics 120:1278–84, 2007). We report a case of unilateral RVT and adrenal hemorrhage in a newborn with homozygous factor V Leiden mutation and heterozygous of the methylene tetrahydrofolate reductase (MTHFR) gene mutations.

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Title: Unilateral Renal Vein Thrombosis and Adrenal Hemorrhage in A Newborn with Homozygous Factor V Leiden and Heterozygous Of MTHFR-677T, MTHFR-1298C Gene Mutations
Authors: Gonca Sandal
Elvan Arıkan
Ayça Esra Kuybulu
Ahmet Rifat Ormecı
Publication date: 01-09-2014
Publisher: Springer India
Published in: Indian Journal of Hematology and Blood Transfusion / Issue Special Issue 1/2014
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI: https://doi.org/10.1007/s12288-014-0364-6

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