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Published in: Current Allergy and Asthma Reports 2/2016

01-02-2016 | Rhinitis (JJ Oppenheimer and J Corren, Section Editors)

Understanding Biofilms in Chronic Sinusitis

Authors: Bobby A. Tajudeen, Joseph S. Schwartz, James N. Palmer

Published in: Current Allergy and Asthma Reports | Issue 2/2016

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Abstract

Chronic sinusitis is a burdensome disease that has substantial individual and societal impact. Although great advances in medical and surgical therapies have been made, some patients continue to have recalcitrant infections. Microbial biofilms have been implicated as a cause of recalcitrant chronic sinusitis, and recent studies have tried to better understand the pathogenesis of chronic sinusitis as it relates to microbial biofilms. Here, we provide an overview of biofilms in chronic sinusitis with emphasis on pathogenesis, treatment, and future directions. In addition, recent evidence is presented, elucidating the role of bitter taste receptors as a possible key factor leading to biofilm formation.
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Metadata
Title
Understanding Biofilms in Chronic Sinusitis
Authors
Bobby A. Tajudeen
Joseph S. Schwartz
James N. Palmer
Publication date
01-02-2016
Publisher
Springer US
Published in
Current Allergy and Asthma Reports / Issue 2/2016
Print ISSN: 1529-7322
Electronic ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-015-0591-4

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