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01-07-2015 | Case Report

Umbilical metastasis derived from breast cancer: report of a case

Authors: Hajime Abe, Keiichi Yamazaki, Tsuyoshi Mori, Yuki Kawai, Yoshihiro Kubota, Tomoko Umeda, Mitsuaki Ishida, Tohru Tani

Published in: Surgery Today | Issue 7/2015

Abstract

Umbilical metastases mainly arise from malignancies of the digestive and gynecological systems, but rarely from breast cancer. A 64-year-old woman with a history of breast cancer was referred to us for investigation of a painful lesion in the umbilicus. Immunohistochemical staining of a specimen obtained by biopsy from the nodule showed umbilical metastasis of breast cancer. After a work up, she was successfully treated with a combination of surgery and endocrine therapy. We report this case to reinforce that not all periumbilical tumoral deposits are consistent.

Shetty MR. Metastatic tumors of the umbilicus: a review 1980-1989. J Surg Oncol. 1990;45:212.PubMedCrossRef

Gabriele R, Conte M, Egidi F, Borghese M. Umbilical metastases: current viewpoint. World J Surg Oncol. 2005;3:13.PubMedCentralPubMedCrossRef

Galvan VG. Sister Mary Jopseph’s nodule. Ann Intern Med. 1998;128:410.PubMedCrossRef

Bailey H. Demonstrations of physical signs in clinical surgery. 11th ed. Baltimore: Williams & Wilkins; 1949. p. 227.

Esserman LJ, Moore DH, Tsing PJ, Chu PW, Yau C, Ozanne E, et al. Biologic markers determine the risk and the timing of recurrence in breast cancer. Breast Cancer Res Treat. 2011;129:607–16.PubMedCentralPubMedCrossRef

Nishimura R, Osako T, Nishiyama Y, Tashima R, Nakano M, Fujisue M, et al. Evaluation of factors related to late recurrence-later than 10 years after the initial treatment-in primary breast cancer. Oncology. 2013;85:100–10.PubMedCrossRef

Srinivasan R, Ray R, Nijhawan R. Metastatic cutaneous and subcutaneous deposits from internal carcinoma. An analysis of cases diagnosed by fine needle aspiration. Acta Cytol. 1993;37:894–8.PubMed

Powell FC, Cooper AJ, Massa MC, Goellner JR, Su WP. Sister Mary Joseph’s nodule: a clinical and histologic study. J Am Acad Dermatol. 1984;10:610–5.PubMedCrossRef

Ching AS, Lai CW. Sonography of umbilical metastasis (Sister Mary Joseph’s nodule) from embryology to imaging. Abdom Imaging. 2002;27:746–9.PubMedCrossRef

10.

Schneider V, Smyczek B. Sister Mary joseph’s nodule. Diagnosis of umbilical metastases by fine needle aspiration. Acta Cytol. 1990;34:555–8.PubMed

11.

Majmudar B, Wiskind AK, Croft BN, Dudley AG. The Sister (Mary) Joseph nodule: its significance in gynecology. Gynecol Oncol. 1991;40:152–9.PubMedCrossRef

12.

Wick MR, Lillemoe TJ, Copland GT, Swanson PE, Manivel JC, Kiang DT. Gross cystic disease fluid protein-15 as a marker for breast cancer immunohistochemical analysis of 690 kuman neoplasms and comparison with alpha-lactalbumin. Hum Pathol. 1989;20:281–7.PubMedCrossRef

13.

Mazoujian G, Bodian C, Haagensen DE Jr, Haagensen CD. Expression of GCDFP-15 in breast carcinoma; relationship to pathologic and clinical factors. Cancer. 1989;63:2156–61.PubMedCrossRef

14.

Chu P, Wu E, Weiss LM. Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases. Mod Pathol. 2000;13:962–72.PubMedCrossRef

15.

NCCN clinical Practice Guidelines in oncology. ver. 3, 2013. Breast Cancer. http://www.nccn.org/professionals/physisician_gls/pdf/breast.pdf

Title: Umbilical metastasis derived from breast cancer: report of a case
Authors: Hajime Abe
Keiichi Yamazaki
Tsuyoshi Mori
Yuki Kawai
Yoshihiro Kubota
Tomoko Umeda
Mitsuaki Ishida
Tohru Tani
Publication date: 01-07-2015
Publisher: Springer Japan
Published in: Surgery Today / Issue 7/2015
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI: https://doi.org/10.1007/s00595-014-0991-4

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Umbilical metastasis derived from breast cancer: report of a case

Abstract

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