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European Radiology

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01-07-2017 | Ultrasound

Ultrasound-guided percutaneous laser ablation of unifocal T1N0M0 papillary thyroid microcarcinoma: Preliminary results

Authors: Wei Zhou, Shan Jiang, Weiwei Zhan, Jianqiao Zhou, Shangyan Xu, Lu Zhang

Published in: European Radiology | Issue 7/2017

Abstract

Objectives

To evaluate the efficacy and safety of percutaneous laser ablation (PLA) for unifocal T1N0M0 papillary thyroid microcarcinoma(PTMC).

Methods

A retrospective study was conducted in 30 patients with single PTMC which was diagnosed by fine-needle aspiration biopsy (FNAB). PLA was performed for proper time to achieve adequate ablation zones. The extent of ablation was assessed by contrast-enhanced ultrasound (CEUS) immediately and 7 days after PLA. Complications were recorded. The size and volume of the ablation area and thyroid hormones were measured, and clinical evaluations were performed at 1, 3, 6 and12 months, and every half year thereafter.

Results

The procedure was well tolerated without serious complications. Of the 30 patients, 29 were treated successfully under local anaesthesia in a single session. Only one incomplete ablation was detected by immediate CEUS after PLA, and a second ablation was performed. At the last follow-up, ten (33.3 %) ablation zones had disappeared, and 20 (66.67 %) ablation zones remained as scar-like lesions. No regrowth of treated tumours, local recurrence or distant metastases were detected.

Conclusions

During the short-term follow-up period, ultrasound-guided PLA appears to be effective and safe for treating solitary T1N0M0 PTMC in selected patients who are ineligible for surgery.

Key Points

• Ultrasound is a useful tool in percutaneous laser ablation (PLA).

• PLA is safe for treating papillary thyroid microcarcinoma.

• PLA is effective for single papillary thyroid microcarcinoma.

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Title: Ultrasound-guided percutaneous laser ablation of unifocal T1N0M0 papillary thyroid microcarcinoma: Preliminary results
Authors: Wei Zhou
Shan Jiang
Weiwei Zhan
Jianqiao Zhou
Shangyan Xu
Lu Zhang
Publication date: 01-07-2017
Publisher: Springer Berlin Heidelberg
Published in: European Radiology / Issue 7/2017
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-016-4610-1

At a glance: The STEP trials

Springer Medicine

Ultrasound-guided percutaneous laser ablation of unifocal T1N0M0 papillary thyroid microcarcinoma: Preliminary results

Abstract

Objectives

Methods

Results

Conclusions

Key Points

At a glance: The STEP trials

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

Key Points

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