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Published in: BMC Health Services Research 1/2015

Open Access 01-06-2015 | Research article

Type 2 diabetes patients’ and providers’ differing perspectives on medication nonadherence: a qualitative meta-synthesis

Authors: Francesca Brundisini, Meredith Vanstone, Danielle Hulan, Deirdre DeJean, Mita Giacomini

Published in: BMC Health Services Research | Issue 1/2015

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Abstract

Background

Poor adherence to medication regimens increases adverse outcomes for patients with Type 2 diabetes. Improving medication adherence is a growing priority for clinicians and health care systems. We examine the differences between patient and provider understandings of barriers to medication adherence for Type 2 diabetes patients.

Methods

We searched systematically for empirical qualitative studies on the topic of barriers to medication adherence among Type 2 diabetes patients published between 2002–2013; 86 empirical qualitative studies qualified for inclusion. Following qualitative meta-synthesis methods, we coded and analyzed thematically the findings from studies, integrating and comparing findings across studies to yield a synthetic interpretation and new insights from this body of research.

Results

We identify 7 categories of barriers: (1) emotional experiences as positive and negative motivators to adherence, (2) intentional non-compliance, (3) patient-provider relationship and communication, (4) information and knowledge, (5) medication administration, (6) social and cultural beliefs, and (7) financial issues. Patients and providers express different understandings of what patients require to improve adherence. Health beliefs, life context and lay understandings all inform patients’ accounts. They describe barriers in terms of difficulties adapting medication regimens to their lifestyles and daily routines. In contrast, providers' understandings of patients poor medication adherence behaviors focus on patients’ presumed needs for more information about the physiological and biomedical aspect of diabetes.

Conclusions

This study highlights key discrepancies between patients’ and providers’ understandings of barriers to medication adherence. These misunderstandings span the many cultural and care contexts represented by 86 qualitative studies. Counseling and interventions aimed at improving medication adherence among Type 2 diabetes might become more effective through better integration of the patient’s perspective and values concerning adherence difficulties and solutions.
Literature
1.
go back to reference Sabate E. Adherence to Long-Term Therapies: Evidence for Action: World Health Organization 2003 Sabate E. Adherence to Long-Term Therapies: Evidence for Action: World Health Organization 2003
3.
go back to reference Global status report on noncommunicable diseases 2010. Geneva, Switzerland: World Health Organization2011 Global status report on noncommunicable diseases 2010. Geneva, Switzerland: World Health Organization2011
4.
go back to reference IDF Diabetes Atlas. Brussels, Belgium: International Diabetes Federation; 2013. IDF Diabetes Atlas. Brussels, Belgium: International Diabetes Federation; 2013.
5.
go back to reference Canada PHAo. Diabetes in Canada: Facts and figures from a public health perspective. Ottawa2011 Canada PHAo. Diabetes in Canada: Facts and figures from a public health perspective. Ottawa2011
6.
go back to reference Cushing A, Metcalfe R. Optimizing medicines management: From compliance to concordance. Ther Clin Risk Manag. 2007;3(6):1047–58.PubMedCentralPubMed Cushing A, Metcalfe R. Optimizing medicines management: From compliance to concordance. Ther Clin Risk Manag. 2007;3(6):1047–58.PubMedCentralPubMed
7.
go back to reference Elwyn G, Edwards A, Britten N. “Doing prescribing”: how might clinicians work differently for better, safer care. Qual Saf Health Care. 2003;12 Suppl 1:i33–6.PubMedCentralPubMedCrossRef Elwyn G, Edwards A, Britten N. “Doing prescribing”: how might clinicians work differently for better, safer care. Qual Saf Health Care. 2003;12 Suppl 1:i33–6.PubMedCentralPubMedCrossRef
8.
go back to reference Haynes RB, McKibbon KA, Kanani R. Systematic review of randomised trials of interventions to assist patients to follow prescriptions for medications. Lancet. 1996;348(9024):383–6.PubMedCrossRef Haynes RB, McKibbon KA, Kanani R. Systematic review of randomised trials of interventions to assist patients to follow prescriptions for medications. Lancet. 1996;348(9024):383–6.PubMedCrossRef
9.
go back to reference van Dulmen S, Sluijs E, van Dijk L, de Ridder D, Heerdink R, Bensing J. Patient adherence to medical treatment: a review of reviews. BMC Health Serv Res. 2007;7(1):55.PubMedCentralPubMedCrossRef van Dulmen S, Sluijs E, van Dijk L, de Ridder D, Heerdink R, Bensing J. Patient adherence to medical treatment: a review of reviews. BMC Health Serv Res. 2007;7(1):55.PubMedCentralPubMedCrossRef
10.
go back to reference Vermeire E, Hearnshaw H, Van Royen P, Denekens J. Patient adherence to treatment: three decades of research. A comprehensive review. J Clin Pharm Ther. 2001;26(5):331–42.PubMedCrossRef Vermeire E, Hearnshaw H, Van Royen P, Denekens J. Patient adherence to treatment: three decades of research. A comprehensive review. J Clin Pharm Ther. 2001;26(5):331–42.PubMedCrossRef
12.
go back to reference DiMatteo MR. Variations in patients’ adherence to medical recommendations: a quantitative review of 50 years of research. Med Care. 2004;42(3):200–9.PubMedCrossRef DiMatteo MR. Variations in patients’ adherence to medical recommendations: a quantitative review of 50 years of research. Med Care. 2004;42(3):200–9.PubMedCrossRef
16.
go back to reference Mead N, Bower P. Patient-centredness: a conceptual framework and review of the empirical literature. Soc Sci Med (1982). 2000;51(7):1087–110.CrossRef Mead N, Bower P. Patient-centredness: a conceptual framework and review of the empirical literature. Soc Sci Med (1982). 2000;51(7):1087–110.CrossRef
18.
go back to reference Hunt LM, Kreiner M, Brody H. The changing face of chronic illness management in primary care: a qualitative study of underlying influences and unintended outcomes. Ann Fam Mede. 2012;10(5):452–60.CrossRef Hunt LM, Kreiner M, Brody H. The changing face of chronic illness management in primary care: a qualitative study of underlying influences and unintended outcomes. Ann Fam Mede. 2012;10(5):452–60.CrossRef
19.
go back to reference Garrett DG, Martin LA. The Asheville Project: participants’ perceptions of factors contributing to the success of a patient self-management diabetes program. J Am Pharm Assoc. 2003;43(2):185–90.CrossRef Garrett DG, Martin LA. The Asheville Project: participants’ perceptions of factors contributing to the success of a patient self-management diabetes program. J Am Pharm Assoc. 2003;43(2):185–90.CrossRef
20.
go back to reference Renfrew MR, Taing E, Cohen MJ, Betancourt JR, Pasinski R, Green AR. Barriers to Care for Cambodian Patients with Diabetes: Results from a Qualitative Study. J Health Care Poor Underserved. 2013;24(2):633–55.PubMedCrossRef Renfrew MR, Taing E, Cohen MJ, Betancourt JR, Pasinski R, Green AR. Barriers to Care for Cambodian Patients with Diabetes: Results from a Qualitative Study. J Health Care Poor Underserved. 2013;24(2):633–55.PubMedCrossRef
21.
go back to reference Vanstone M, Brundisini F, Hulan D, DeJean D, Giacomini M. Patient Experiences of Medication Adherence: A Systematic Review and Qualitative Meta-Synthesis. Toronto, ON.2014 Vanstone M, Brundisini F, Hulan D, DeJean D, Giacomini M. Patient Experiences of Medication Adherence: A Systematic Review and Qualitative Meta-Synthesis. Toronto, ON.2014
22.
go back to reference Shaw RL, Booth A, Sutton AJ, Miller T, Smith JA, Young B, et al. Finding qualitative research: an evaluation of search strategies. BMC Med Res Methodol. 2004;4(1):5.PubMedCentralPubMedCrossRef Shaw RL, Booth A, Sutton AJ, Miller T, Smith JA, Young B, et al. Finding qualitative research: an evaluation of search strategies. BMC Med Res Methodol. 2004;4(1):5.PubMedCentralPubMedCrossRef
23.
go back to reference Wilczynski NL, Marks S, Haynes RB. Search strategies for identifying qualitative studies in CINAHL. Qual Health Res. 2007;17(5):705–10.PubMedCrossRef Wilczynski NL, Marks S, Haynes RB. Search strategies for identifying qualitative studies in CINAHL. Qual Health Res. 2007;17(5):705–10.PubMedCrossRef
24.
go back to reference Wong S, Wilczynski NL, Haynes RB. Developing optimal search strategies for detecting clinically relevant qualitative studies in MEDLINE. Medinfo. 2004;11(pt 1):311–6. Wong S, Wilczynski NL, Haynes RB. Developing optimal search strategies for detecting clinically relevant qualitative studies in MEDLINE. Medinfo. 2004;11(pt 1):311–6.
25.
go back to reference Sandelowski M, Barroso J. Creating metasummaries of qualitative findings. Nursing Res. 2003;52(4):226–33.CrossRef Sandelowski M, Barroso J. Creating metasummaries of qualitative findings. Nursing Res. 2003;52(4):226–33.CrossRef
27.
go back to reference Sandelowski M, Barroso J. Handbook for synthesizing qualitative research. New York, NY: Springer Pub. Co.; 2006. Sandelowski M, Barroso J. Handbook for synthesizing qualitative research. New York, NY: Springer Pub. Co.; 2006.
28.
go back to reference Saini M, Shlonsky A. Systematic synthesis of qualitative research. Pocket Guides to Social Research Methods. New York: Oxford University Press; 2012.CrossRef Saini M, Shlonsky A. Systematic synthesis of qualitative research. Pocket Guides to Social Research Methods. New York: Oxford University Press; 2012.CrossRef
29.
go back to reference Melia KM. Recognizing quality in qualitative research. In: Bourgeault IL, DeVries R, Dingwall R, editors. SAGE Handbook of Qualitative Health Research. Thousand Oaks: Sage; 2010. p. 559–74.CrossRef Melia KM. Recognizing quality in qualitative research. In: Bourgeault IL, DeVries R, Dingwall R, editors. SAGE Handbook of Qualitative Health Research. Thousand Oaks: Sage; 2010. p. 559–74.CrossRef
32.
go back to reference Noblit G, Hare RD. Meta-ethnography: Synthesizing qualitative studies. Newbury Park: Sage Publications; 1988. Noblit G, Hare RD. Meta-ethnography: Synthesizing qualitative studies. Newbury Park: Sage Publications; 1988.
33.
go back to reference Paterson B. Coming out as ill: understanding self-disclosure in chronic illness from a meta-synthesis of qualitative research. Reviewing Research Evidence for Nursing Practice. 2007:73–83 Paterson B. Coming out as ill: understanding self-disclosure in chronic illness from a meta-synthesis of qualitative research. Reviewing Research Evidence for Nursing Practice. 2007:73–83
34.
go back to reference Sandelowski M, Barroso J. Finding the findings in qualitative studies. J Nurs Scholarsh. 2002;34(3):213–9.PubMedCrossRef Sandelowski M, Barroso J. Finding the findings in qualitative studies. J Nurs Scholarsh. 2002;34(3):213–9.PubMedCrossRef
35.
go back to reference Charmaz K. Constructing grounded theory : a practical guide through qualitative analysis. London: Sage Publications; 2006. Charmaz K. Constructing grounded theory : a practical guide through qualitative analysis. London: Sage Publications; 2006.
36.
go back to reference Corbin JM. Basics of qualitative research : techniques and procedures for developing grounded theory. 3rd ed. ed. Los Angeles: Sage Publications Inc.; 2008. Corbin JM. Basics of qualitative research : techniques and procedures for developing grounded theory. 3rd ed. ed. Los Angeles: Sage Publications Inc.; 2008.
38.
go back to reference Noakes H. Perceptions of black African and African-Caribbean people regarding insulin. J Diab Nurs. 2010;14(4):148. Noakes H. Perceptions of black African and African-Caribbean people regarding insulin. J Diab Nurs. 2010;14(4):148.
39.
go back to reference Parry O, Peel E, Douglas M, Lawton J. Issues of cause and control in patient accounts of Type 2 diabetes. Health Educ Res. 2006;21(1):97–107.PubMedCrossRef Parry O, Peel E, Douglas M, Lawton J. Issues of cause and control in patient accounts of Type 2 diabetes. Health Educ Res. 2006;21(1):97–107.PubMedCrossRef
40.
go back to reference Wong M, Haswell-Elkins M, Tamwoy E, McDermott R, D’Abbs P. Perspectives on clinic attendance, medication and foot-care among people with diabetes in the Torres Strait Islands and Northern Peninsula Area. Aust J Rural Health. 2005;13(3):172–7.PubMedCrossRef Wong M, Haswell-Elkins M, Tamwoy E, McDermott R, D’Abbs P. Perspectives on clinic attendance, medication and foot-care among people with diabetes in the Torres Strait Islands and Northern Peninsula Area. Aust J Rural Health. 2005;13(3):172–7.PubMedCrossRef
41.
go back to reference Morris JE, Povey RC, Street CG. Experiences of people with type 2 diabetes who have changed from oral medication to self-administered insulin injections: a qualitative study. Practical Diabetes International. 2005;22(7):239–43.CrossRef Morris JE, Povey RC, Street CG. Experiences of people with type 2 diabetes who have changed from oral medication to self-administered insulin injections: a qualitative study. Practical Diabetes International. 2005;22(7):239–43.CrossRef
42.
43.
go back to reference Lee DY, Armour C, Krass I. The development and evaluation of written medicines information for type 2 diabetes. Health Educ Res. 2007;22(6):918–30.PubMedCrossRef Lee DY, Armour C, Krass I. The development and evaluation of written medicines information for type 2 diabetes. Health Educ Res. 2007;22(6):918–30.PubMedCrossRef
44.
go back to reference Nair KM, Levine MA, Lohfeld LH, Gerstein HC. “I take what I think works for me”: a qualitative study to explore patient perception of diabetes treatment benefits and risks. Can J Clin Pharmacol. 2007;14(2):e251–9.PubMed Nair KM, Levine MA, Lohfeld LH, Gerstein HC. “I take what I think works for me”: a qualitative study to explore patient perception of diabetes treatment benefits and risks. Can J Clin Pharmacol. 2007;14(2):e251–9.PubMed
46.
go back to reference Cardol M, Rijken M, van Schrojenstein Lantman-de Valk H. People with mild to moderate intellectual disability talking about their diabetes and how they manage. J Intellect Disabil Res. 2012;56(4):351–60.PubMedCrossRef Cardol M, Rijken M, van Schrojenstein Lantman-de Valk H. People with mild to moderate intellectual disability talking about their diabetes and how they manage. J Intellect Disabil Res. 2012;56(4):351–60.PubMedCrossRef
48.
go back to reference Goering EM, Matthias MS. Coping with chronic illness: information use and treatment adherence among people with diabetes. Commun Medicine. 2010;7(2):107–18. Goering EM, Matthias MS. Coping with chronic illness: information use and treatment adherence among people with diabetes. Commun Medicine. 2010;7(2):107–18.
49.
go back to reference Mathew R, Gucciardi E, De Melo M, Barata P. Self-management experiences among men and women with type 2 diabetes mellitus: a qualitative analysis. BMC Fam Pract. 2012;13:122.PubMedCentralPubMedCrossRef Mathew R, Gucciardi E, De Melo M, Barata P. Self-management experiences among men and women with type 2 diabetes mellitus: a qualitative analysis. BMC Fam Pract. 2012;13:122.PubMedCentralPubMedCrossRef
50.
go back to reference Mishra SI, Gioia D, Childress S, Barnet B, Webster RL. Adherence to Medication Regimens among Low-Income Patients with Multiple Comorbid Chronic Conditions. Health Soc Work. 2011;36(4):249–58.PubMedCentralPubMedCrossRef Mishra SI, Gioia D, Childress S, Barnet B, Webster RL. Adherence to Medication Regimens among Low-Income Patients with Multiple Comorbid Chronic Conditions. Health Soc Work. 2011;36(4):249–58.PubMedCentralPubMedCrossRef
51.
go back to reference Moser A, van der Bruggen H, Widdershoven G, Spreeuwenberg C. Self-management of type 2 diabetes mellitus: a qualitative investigation from the perspective of participants in a nurse-led, shared-care programme in the Netherlands. BMC Public Health. 2008;8:91.PubMedCentralPubMedCrossRef Moser A, van der Bruggen H, Widdershoven G, Spreeuwenberg C. Self-management of type 2 diabetes mellitus: a qualitative investigation from the perspective of participants in a nurse-led, shared-care programme in the Netherlands. BMC Public Health. 2008;8:91.PubMedCentralPubMedCrossRef
52.
go back to reference Vinter-Repalust N, Petricek G, Katic M. Obstacles which patients with type 2 diabetes meet while adhering to the therapeutic regimen in everyday life: qualitative study. Croat Med J. 2004;45(5):630–6.PubMed Vinter-Repalust N, Petricek G, Katic M. Obstacles which patients with type 2 diabetes meet while adhering to the therapeutic regimen in everyday life: qualitative study. Croat Med J. 2004;45(5):630–6.PubMed
53.
go back to reference Barton SS, Anderson N, Thommasen HV. The diabetes experiences of Aboriginal people living in a rural Canadian community. Aust J Rural Health. 2005;13(4):242–6.PubMedCrossRef Barton SS, Anderson N, Thommasen HV. The diabetes experiences of Aboriginal people living in a rural Canadian community. Aust J Rural Health. 2005;13(4):242–6.PubMedCrossRef
54.
go back to reference Felea MG, Covrig M, Manea DI, Titan E. Perceptions of Life Burdens and of the Positive Side of Life in a Group of Elderly Patients with Diabetes: A Qualitative Analysis through Grounded Theory. Rev Cercet Interv Soc. 2013;40:7–20. Felea MG, Covrig M, Manea DI, Titan E. Perceptions of Life Burdens and of the Positive Side of Life in a Group of Elderly Patients with Diabetes: A Qualitative Analysis through Grounded Theory. Rev Cercet Interv Soc. 2013;40:7–20.
56.
go back to reference Helsel D, Mochel M, Bauer R. Chronic illness and Hmong shamans. J Transcult Nurs. 2005;16(2):150–4.PubMedCrossRef Helsel D, Mochel M, Bauer R. Chronic illness and Hmong shamans. J Transcult Nurs. 2005;16(2):150–4.PubMedCrossRef
57.
go back to reference Morrow AS, Haidet P, Skinner J, Naik AD. Integrating diabetes self-management with the health goals of older adults: a qualitative exploration. Patient Educ Couns. 2008;72(3):418–23.PubMedCentralPubMedCrossRef Morrow AS, Haidet P, Skinner J, Naik AD. Integrating diabetes self-management with the health goals of older adults: a qualitative exploration. Patient Educ Couns. 2008;72(3):418–23.PubMedCentralPubMedCrossRef
58.
go back to reference Bogatean MP, H√¢ncu N. People with type 2 diabetes facing the reality of starting insulin therapy: factors involved in psychological insulin resistance. Pract Diabetes Int. 2004;21(7):247–52.CrossRef Bogatean MP, H√¢ncu N. People with type 2 diabetes facing the reality of starting insulin therapy: factors involved in psychological insulin resistance. Pract Diabetes Int. 2004;21(7):247–52.CrossRef
59.
go back to reference Borgsteede SD, Westerman MJ, Kok IL, Meeuse JC, de Vries T, Hugtenburg JG. Factors related to high and low levels of drug adherence according to patients with type 2 diabetes. Int J Clin Phar. 2011;33(5):779–87. doi:10.1007/s11096-011-9534-x.CrossRef Borgsteede SD, Westerman MJ, Kok IL, Meeuse JC, de Vries T, Hugtenburg JG. Factors related to high and low levels of drug adherence according to patients with type 2 diabetes. Int J Clin Phar. 2011;33(5):779–87. doi:10.​1007/​s11096-011-9534-x.CrossRef
60.
go back to reference George SR, Thomas SP. Lived experience of diabetes among older, rural people. J Adv Nurs. 2010;66(5):1092–100.PubMedCrossRef George SR, Thomas SP. Lived experience of diabetes among older, rural people. J Adv Nurs. 2010;66(5):1092–100.PubMedCrossRef
62.
go back to reference Lawton J, Ahmad N, Hallowell N, Hanna L, Douglas M. Perceptions and experiences of taking oral hypoglycaemic agents among people of Pakistani and Indian origin: qualitative study. BMJ. 2005;330(7502):28.CrossRef Lawton J, Ahmad N, Hallowell N, Hanna L, Douglas M. Perceptions and experiences of taking oral hypoglycaemic agents among people of Pakistani and Indian origin: qualitative study. BMJ. 2005;330(7502):28.CrossRef
63.
go back to reference Rise MB, Pellerud A, Rygg LO, Steinsbekk A. Making and Maintaining Lifestyle Changes after Participating in Group Based Type 2 Diabetes Self-Management Educations: A Qualitative Study. PLoS One. 2013;8(5):7. doi:10.1371/journal.pone.0064009.CrossRef Rise MB, Pellerud A, Rygg LO, Steinsbekk A. Making and Maintaining Lifestyle Changes after Participating in Group Based Type 2 Diabetes Self-Management Educations: A Qualitative Study. PLoS One. 2013;8(5):7. doi:10.​1371/​journal.​pone.​0064009.CrossRef
64.
go back to reference Tjia J, Givens JL, Karlawish JH, Okoli-Umeweni A, Barg FK. Beneath the surface: discovering the unvoiced concerns of older adults with type 2 diabetes mellitus. Health Educ Res. 2008;23(1):40–52.PubMedCrossRef Tjia J, Givens JL, Karlawish JH, Okoli-Umeweni A, Barg FK. Beneath the surface: discovering the unvoiced concerns of older adults with type 2 diabetes mellitus. Health Educ Res. 2008;23(1):40–52.PubMedCrossRef
65.
go back to reference Shaw JL, Brown J, Khan B, Mau MK, Dillard D. Resources, roadblocks and turning points: a qualitative study of American Indian/Alaska Native adults with type 2 diabetes. J Community Health. 2013;38(1):86–94.PubMedCrossRef Shaw JL, Brown J, Khan B, Mau MK, Dillard D. Resources, roadblocks and turning points: a qualitative study of American Indian/Alaska Native adults with type 2 diabetes. J Community Health. 2013;38(1):86–94.PubMedCrossRef
66.
68.
70.
go back to reference Nagelkerk J, Reick K, Meengs L. Perceived barriers and effective strategies to diabetes self-management. J Adv Nurs. 2006;54(2):151–8.PubMedCrossRef Nagelkerk J, Reick K, Meengs L. Perceived barriers and effective strategies to diabetes self-management. J Adv Nurs. 2006;54(2):151–8.PubMedCrossRef
71.
go back to reference Brown K, Avis M, Hubbard M. Health beliefs of African-Caribbean people with type 2 diabetes: a qualitative study. Br J Gen Pract. 2007;57(539):461–9.PubMedCentralPubMed Brown K, Avis M, Hubbard M. Health beliefs of African-Caribbean people with type 2 diabetes: a qualitative study. Br J Gen Pract. 2007;57(539):461–9.PubMedCentralPubMed
72.
go back to reference Grant RW, Pabon-Nau L, Ross KM, Youatt EJ, Pandiscio JC, Park ER. Diabetes oral medication initiation and intensification: patient views compared with current treatment guidelines. Diabetes Educ. 2011;37(1):78–84.PubMedCentralPubMedCrossRef Grant RW, Pabon-Nau L, Ross KM, Youatt EJ, Pandiscio JC, Park ER. Diabetes oral medication initiation and intensification: patient views compared with current treatment guidelines. Diabetes Educ. 2011;37(1):78–84.PubMedCentralPubMedCrossRef
73.
go back to reference Hayes RP, Bowman L, Monahan PO, Marrero DG, McHorney CA. Understanding diabetes medications from the perspective of patients with type 2 diabetes: prerequisite to medication concordance. Diabetes Educ. 2006;32(3):404–14.PubMedCrossRef Hayes RP, Bowman L, Monahan PO, Marrero DG, McHorney CA. Understanding diabetes medications from the perspective of patients with type 2 diabetes: prerequisite to medication concordance. Diabetes Educ. 2006;32(3):404–14.PubMedCrossRef
74.
go back to reference Henderson LC. Divergent models of diabetes among American Indian elders. J Cross Cult Gerontol. 2010;25(4):303–16.PubMedCrossRef Henderson LC. Divergent models of diabetes among American Indian elders. J Cross Cult Gerontol. 2010;25(4):303–16.PubMedCrossRef
75.
go back to reference Lutfey K. On practices of ‘good doctoring’: reconsidering the relationship between provider roles and patient adherence. Sociol Health Illn. 2005;27(4):421–47.PubMedCrossRef Lutfey K. On practices of ‘good doctoring’: reconsidering the relationship between provider roles and patient adherence. Sociol Health Illn. 2005;27(4):421–47.PubMedCrossRef
76.
go back to reference Rahim-Williams B. Beliefs, behaviors, and modifications of type 2 diabetes self-management among African American women. J Natl Med Assoc. 2011;103(3):203–15.PubMedCrossRef Rahim-Williams B. Beliefs, behaviors, and modifications of type 2 diabetes self-management among African American women. J Natl Med Assoc. 2011;103(3):203–15.PubMedCrossRef
79.
go back to reference Mc Sharry J, Bishop FL, Moss-Morris R, Kendrick T. ‘The chicken and egg thing’: cognitive representations and self-management of multimorbidity in people with diabetes and depression. Psychol Health. 2013;28(1):103–19.PubMedCrossRef Mc Sharry J, Bishop FL, Moss-Morris R, Kendrick T. ‘The chicken and egg thing’: cognitive representations and self-management of multimorbidity in people with diabetes and depression. Psychol Health. 2013;28(1):103–19.PubMedCrossRef
80.
go back to reference Stack RJ, Elliott RA, Noyce PR, Bundy C. A qualitative exploration of multiple medicines beliefs in co-morbid diabetes and cardiovascular disease. Diabetic Med. 2008;25(10):1204–10.PubMedCrossRef Stack RJ, Elliott RA, Noyce PR, Bundy C. A qualitative exploration of multiple medicines beliefs in co-morbid diabetes and cardiovascular disease. Diabetic Med. 2008;25(10):1204–10.PubMedCrossRef
82.
go back to reference Agarwal G, Nair K, Cosby J, Dolovich L, Levine M, Kaczorowski J, et al. GPs’ approach to insulin prescribing in older patients: a qualitative study. Br J Gen Pract. 2008;58(553):569–75.PubMedCentralPubMedCrossRef Agarwal G, Nair K, Cosby J, Dolovich L, Levine M, Kaczorowski J, et al. GPs’ approach to insulin prescribing in older patients: a qualitative study. Br J Gen Pract. 2008;58(553):569–75.PubMedCentralPubMedCrossRef
83.
go back to reference Brown JB, Harris SB, Webster-Bogaert S, Wetmore S, Faulds C, Stewart M. The role of patient, physician and systemic factors in the management of type 2 diabetes mellitus. Fam Pract. 2002;19(4):344–9.PubMedCrossRef Brown JB, Harris SB, Webster-Bogaert S, Wetmore S, Faulds C, Stewart M. The role of patient, physician and systemic factors in the management of type 2 diabetes mellitus. Fam Pract. 2002;19(4):344–9.PubMedCrossRef
84.
go back to reference Jeavons D, Hungin AP, Cornford CS. Patients with poorly controlled diabetes in primary care: healthcare clinicians’ beliefs and attitudes. Postgrad Med J. 2006;82(967):347–50.PubMedCentralPubMedCrossRef Jeavons D, Hungin AP, Cornford CS. Patients with poorly controlled diabetes in primary care: healthcare clinicians’ beliefs and attitudes. Postgrad Med J. 2006;82(967):347–50.PubMedCentralPubMedCrossRef
85.
go back to reference Wens J, Vermeire E, Royen PV, Sabbe B, Denekens J. GPs’ perspectives of type 2 diabetes patients’ adherence to treatment: A qualitative analysis of barriers and solutions. BMC Fam Pract. 2005;6(1):12.CrossRef Wens J, Vermeire E, Royen PV, Sabbe B, Denekens J. GPs’ perspectives of type 2 diabetes patients’ adherence to treatment: A qualitative analysis of barriers and solutions. BMC Fam Pract. 2005;6(1):12.CrossRef
86.
go back to reference Phillips A. Starting patients on insulin therapy: diabetes nurse specialist views. Nurs Stand. 2007;21(30):35–40.CrossRef Phillips A. Starting patients on insulin therapy: diabetes nurse specialist views. Nurs Stand. 2007;21(30):35–40.CrossRef
87.
go back to reference Connor U, Anton M, Goering E, Lauten K, Hayat A, Roach P, et al. Listening to patients’ voices: linguistic indicators related to diabetes self-management. Commun Med. 2012;9(1):1–12.PubMed Connor U, Anton M, Goering E, Lauten K, Hayat A, Roach P, et al. Listening to patients’ voices: linguistic indicators related to diabetes self-management. Commun Med. 2012;9(1):1–12.PubMed
88.
go back to reference Ho EY, James J. Cultural barriers to initiating insulin therapy in Chinese people with type 2 diabetes living in Canada. Can J Diab. 2006;30(4):390–6.CrossRef Ho EY, James J. Cultural barriers to initiating insulin therapy in Chinese people with type 2 diabetes living in Canada. Can J Diab. 2006;30(4):390–6.CrossRef
89.
go back to reference Lynch EB, Fernandez A, Lighthouse N, Mendenhall E, Jacobs E. Concepts of diabetes self-management in Mexican American and African American low-income patients with diabetes. Health Educ Res. 2012;27(5):814–24.PubMedCrossRef Lynch EB, Fernandez A, Lighthouse N, Mendenhall E, Jacobs E. Concepts of diabetes self-management in Mexican American and African American low-income patients with diabetes. Health Educ Res. 2012;27(5):814–24.PubMedCrossRef
91.
go back to reference Mohan AV, Riley MB, Boyington DR, Kripalani S. Illustrated medication instructions as a strategy to improve medication management among Latinos: a qualitative analysis. J Health Psychol. 2013;18(2):187–97.PubMedCentralPubMedCrossRef Mohan AV, Riley MB, Boyington DR, Kripalani S. Illustrated medication instructions as a strategy to improve medication management among Latinos: a qualitative analysis. J Health Psychol. 2013;18(2):187–97.PubMedCentralPubMedCrossRef
92.
go back to reference Barko R, Corbett CF, Allen CB, Shultz JA. Perceptions of diabetes symptoms and self-management strategies: a cross-cultural comparison. J Transcult Nurs. 2011;22(3):274–81.PubMedCrossRef Barko R, Corbett CF, Allen CB, Shultz JA. Perceptions of diabetes symptoms and self-management strategies: a cross-cultural comparison. J Transcult Nurs. 2011;22(3):274–81.PubMedCrossRef
94.
go back to reference Wang Y, Chuang L, Bateman WB. Focus group study assessing self-management skills of Chinese Americans with type 2 diabetes mellitus. J Immigr Minor Health. 2012;14(5):869–74.PubMedCrossRef Wang Y, Chuang L, Bateman WB. Focus group study assessing self-management skills of Chinese Americans with type 2 diabetes mellitus. J Immigr Minor Health. 2012;14(5):869–74.PubMedCrossRef
95.
go back to reference Ab E, Denig P, van Vliet T, Dekker JH. Reasons of general practitioners for not prescribing lipid-lowering medication to patients with diabetes: a qualitative study. BMC Fam Pract. 2009;10:24.PubMedCentralPubMedCrossRef Ab E, Denig P, van Vliet T, Dekker JH. Reasons of general practitioners for not prescribing lipid-lowering medication to patients with diabetes: a qualitative study. BMC Fam Pract. 2009;10:24.PubMedCentralPubMedCrossRef
96.
go back to reference Venkatesh S, Weatherspoon L. Social and health care provider support in diabetes self-management. Am J Health Behav. 2013;37(1):112–21.PubMedCrossRef Venkatesh S, Weatherspoon L. Social and health care provider support in diabetes self-management. Am J Health Behav. 2013;37(1):112–21.PubMedCrossRef
97.
go back to reference Vermeire E, Hearnshaw H, Ratsep A, Levasseur G, Petek D, van Dam H, et al. Obstacles to adherence in living with type-2 diabetes: an international qualitative study using meta-ethnography (EUROBSTACLE). Prim Care Diabetes. 2007;1(1):25–33.PubMedCrossRef Vermeire E, Hearnshaw H, Ratsep A, Levasseur G, Petek D, van Dam H, et al. Obstacles to adherence in living with type-2 diabetes: an international qualitative study using meta-ethnography (EUROBSTACLE). Prim Care Diabetes. 2007;1(1):25–33.PubMedCrossRef
98.
go back to reference Courtenay M, Stenner K, Carey N. The views of patients with diabetes about nurse prescribing. Diabetic Med. 2010;27(9):1049–54.PubMedCrossRef Courtenay M, Stenner K, Carey N. The views of patients with diabetes about nurse prescribing. Diabetic Med. 2010;27(9):1049–54.PubMedCrossRef
99.
go back to reference Onwudiwe NC, Mullins CD, Winston RA, Shaya FT, Pradel FG, Laird A, et al. Barriers to self-management of diabetes: a qualitative study among low-income minority diabetics. Ethnicity & Disease. 2011;21(1):27–32. Onwudiwe NC, Mullins CD, Winston RA, Shaya FT, Pradel FG, Laird A, et al. Barriers to self-management of diabetes: a qualitative study among low-income minority diabetics. Ethnicity & Disease. 2011;21(1):27–32.
100.
go back to reference Jenkins N, Hallowell N, Farmer AJ, Holman RR, Lawton J. Participants’ experiences of intensifying insulin therapy during the Treating to Target in Type 2 Diabetes (4-T) trial: qualitative interview study. Diabetic Med. 2011;28(5):543–8.PubMedCrossRef Jenkins N, Hallowell N, Farmer AJ, Holman RR, Lawton J. Participants’ experiences of intensifying insulin therapy during the Treating to Target in Type 2 Diabetes (4-T) trial: qualitative interview study. Diabetic Med. 2011;28(5):543–8.PubMedCrossRef
102.
go back to reference Rayman K, Ellison G. Home alone: the experience of women with type 2 diabetes who are new to intensive control. Health Care Women Int. 2004;25(10):900–15.PubMedCrossRef Rayman K, Ellison G. Home alone: the experience of women with type 2 diabetes who are new to intensive control. Health Care Women Int. 2004;25(10):900–15.PubMedCrossRef
104.
go back to reference Wilson PM, Kataria N, McNeilly E. Patient and carer experience of obtaining regular prescribed medication for chronic disease in the English National Health Service: a qualitative study. BMC Health Serv Res. 2013;13:11. doi:10.1186/1472-6963-13-192.CrossRef Wilson PM, Kataria N, McNeilly E. Patient and carer experience of obtaining regular prescribed medication for chronic disease in the English National Health Service: a qualitative study. BMC Health Serv Res. 2013;13:11. doi:10.​1186/​1472-6963-13-192.CrossRef
107.
go back to reference Guell C. Self-care at the margins: meals and meters in migrants’ diabetes tactics. Med Anthropol Q. 2012;26(4):518–33.PubMedCrossRef Guell C. Self-care at the margins: meals and meters in migrants’ diabetes tactics. Med Anthropol Q. 2012;26(4):518–33.PubMedCrossRef
108.
go back to reference Frandsen KB, Kristensen JS. Diet and lifestyle in type 2 diabetes: the patient’s perspective. Pract Diab Int. 2002;19(3):77–80.CrossRef Frandsen KB, Kristensen JS. Diet and lifestyle in type 2 diabetes: the patient’s perspective. Pract Diab Int. 2002;19(3):77–80.CrossRef
109.
go back to reference Borovoy A, Hine J. Managing the unmanageable: elderly Russian Jewish emigres and the biomedical culture of diabetes care. Med Anthropol Q. 2008;22(1):1–26.PubMedCrossRef Borovoy A, Hine J. Managing the unmanageable: elderly Russian Jewish emigres and the biomedical culture of diabetes care. Med Anthropol Q. 2008;22(1):1–26.PubMedCrossRef
110.
go back to reference Patel N, Stone MA, Chauhan A, Davies MJ, Khunti K. Insulin initiation and management in people with Type 2 diabetes in an ethnically diverse population: the healthcare provider perspective. Diabetic Med. 2012;29(10):1311–6.PubMedCrossRef Patel N, Stone MA, Chauhan A, Davies MJ, Khunti K. Insulin initiation and management in people with Type 2 diabetes in an ethnically diverse population: the healthcare provider perspective. Diabetic Med. 2012;29(10):1311–6.PubMedCrossRef
111.
go back to reference Sibley A, Latter S, Richard C, Lussier MT, Roberge D, Skinner TC, et al. Medication discussion between nurse prescribers and people with diabetes: an analysis of content and participation using MEDICODE. J Adv Nurs. 2011;67:2323–36.PubMedCrossRef Sibley A, Latter S, Richard C, Lussier MT, Roberge D, Skinner TC, et al. Medication discussion between nurse prescribers and people with diabetes: an analysis of content and participation using MEDICODE. J Adv Nurs. 2011;67:2323–36.PubMedCrossRef
112.
go back to reference Thorlby R, Jorgensen S, Ayanian JZ, Sequist TD. Clinicians’ views of an intervention to reduce racial disparities in diabetes outcomes. J Natl Med Assoc. 2011;103(9–10):968–77.PubMedCentralPubMedCrossRef Thorlby R, Jorgensen S, Ayanian JZ, Sequist TD. Clinicians’ views of an intervention to reduce racial disparities in diabetes outcomes. J Natl Med Assoc. 2011;103(9–10):968–77.PubMedCentralPubMedCrossRef
114.
go back to reference Lippa KD, Klein HA. Portraits of patient cognition: how patients understand diabetes self-care. Can J Nurs Res. 2008;40(3):80–95.PubMed Lippa KD, Klein HA. Portraits of patient cognition: how patients understand diabetes self-care. Can J Nurs Res. 2008;40(3):80–95.PubMed
115.
go back to reference Lippa KD, Klein HA, Shalin VL. Everyday expertise: cognitive demands in diabetes selfmanagement. Hum Factors. 2008;50(1):112–20.PubMedCrossRef Lippa KD, Klein HA, Shalin VL. Everyday expertise: cognitive demands in diabetes selfmanagement. Hum Factors. 2008;50(1):112–20.PubMedCrossRef
116.
go back to reference Coronado GD, Thompson B, Tejeda S, Godina R. Attitudes and beliefs among Mexican Americans about type 2 diabetes. J Health Care Poor Underserved. 2004;15(4):576–88.PubMedCrossRef Coronado GD, Thompson B, Tejeda S, Godina R. Attitudes and beliefs among Mexican Americans about type 2 diabetes. J Health Care Poor Underserved. 2004;15(4):576–88.PubMedCrossRef
117.
go back to reference Bhattacharya G. Self-management of type 2 diabetes among African Americans in the Arkansas Delta: a strengths perspective in social-cultural context. J Health Care Poor Underserved. 2012;23(1):161–78.PubMedCrossRef Bhattacharya G. Self-management of type 2 diabetes among African Americans in the Arkansas Delta: a strengths perspective in social-cultural context. J Health Care Poor Underserved. 2012;23(1):161–78.PubMedCrossRef
118.
go back to reference Mayberry LS, Osborn CY. Family support, medication adherence, and glycemic control among adults with type 2 diabetes. Diabetes Care. 2012;35(6):1239–45.PubMedCentralPubMedCrossRef Mayberry LS, Osborn CY. Family support, medication adherence, and glycemic control among adults with type 2 diabetes. Diabetes Care. 2012;35(6):1239–45.PubMedCentralPubMedCrossRef
119.
go back to reference Raphael D, Daiski I, Pilkington B, Bryant T, Dinca-Panaitescu M, Dinca-Panaitescu S. A toxic combination of poor social policies and programmes, unfair economic arrangements and bad politics: the experiences of poor Canadians with Type 2 diabetes. Critical Public Health. 2012;22(2):127–45. doi:10.1080/09581596.2011.607797.CrossRef Raphael D, Daiski I, Pilkington B, Bryant T, Dinca-Panaitescu M, Dinca-Panaitescu S. A toxic combination of poor social policies and programmes, unfair economic arrangements and bad politics: the experiences of poor Canadians with Type 2 diabetes. Critical Public Health. 2012;22(2):127–45. doi:10.​1080/​09581596.​2011.​607797.CrossRef
120.
go back to reference Bezreh T, Laws MB, Taubin T, Rifkin DE, Wilson IB. Challenges to physician–patient communication about medication use: a window into the skeptical patient’s world. Patient preference and adherence. 2012;6:11–8. doi:10.2147/PPA.S25971.PubMedCentralPubMed Bezreh T, Laws MB, Taubin T, Rifkin DE, Wilson IB. Challenges to physician–patient communication about medication use: a window into the skeptical patient’s world. Patient preference and adherence. 2012;6:11–8. doi:10.​2147/​PPA.​S25971.PubMedCentralPubMed
122.
go back to reference Vermeire E, Hearnshaw H, Ratsep A, Levasseur G, Petek D, van Dam H, et al. Obstacles to adherence in living with type-2 diabetes: an international qualitative study using meta-ethnography (EUROBSTACLE). Prim Care Diabetes. 2007;1(1):25–33. doi:10.1016/j.pcd.2006.07.002.PubMedCrossRef Vermeire E, Hearnshaw H, Ratsep A, Levasseur G, Petek D, van Dam H, et al. Obstacles to adherence in living with type-2 diabetes: an international qualitative study using meta-ethnography (EUROBSTACLE). Prim Care Diabetes. 2007;1(1):25–33. doi:10.​1016/​j.​pcd.​2006.​07.​002.PubMedCrossRef
124.
go back to reference Institute of Medicine Committee on Quality of Health Care in A. Crossing the Quality Chasm: A New Health System for the 21st Century. Washington (DC): National Academies Press (US); 2001. Copyright 2001 by the National Academy of Sciences. All rights reserved. Institute of Medicine Committee on Quality of Health Care in A. Crossing the Quality Chasm: A New Health System for the 21st Century. Washington (DC): National Academies Press (US); 2001. Copyright 2001 by the National Academy of Sciences. All rights reserved.
125.
go back to reference Sondergaard E, Willadsen TG, Guassora AD, Vestergaard M, Tomasdottir MO, Borgquist L, et al. Problems and challenges in relation to the treatment of patients with multimorbidity: General practitioners’ views and attitudes. Scand J Prim Health Care. 2015;33(2):121–6. doi:10.3109/02813432.2015.1041828.PubMed Sondergaard E, Willadsen TG, Guassora AD, Vestergaard M, Tomasdottir MO, Borgquist L, et al. Problems and challenges in relation to the treatment of patients with multimorbidity: General practitioners’ views and attitudes. Scand J Prim Health Care. 2015;33(2):121–6. doi:10.​3109/​02813432.​2015.​1041828.PubMed
126.
go back to reference Krall J, Gabbay R, Zickmund S, Hamm ME, Williams KR, Siminerio L. Current perspectives on psychological insulin resistance: primary care provider and patient views. Diabetes Technol Ther. 2015;17(4):268–74. doi:10.1089/dia.2014.0268.PubMedCrossRef Krall J, Gabbay R, Zickmund S, Hamm ME, Williams KR, Siminerio L. Current perspectives on psychological insulin resistance: primary care provider and patient views. Diabetes Technol Ther. 2015;17(4):268–74. doi:10.​1089/​dia.​2014.​0268.PubMedCrossRef
128.
go back to reference Jones L, Crabb S, Turnbull D, Oxlad M. Barriers and facilitators to effective type 2 diabetes management in a rural context: a qualitative study with diabetic patients and health professionals. J Health Psychol. 2014;19(3):441–53. doi:10.1177/1359105312473786.PubMedCrossRef Jones L, Crabb S, Turnbull D, Oxlad M. Barriers and facilitators to effective type 2 diabetes management in a rural context: a qualitative study with diabetic patients and health professionals. J Health Psychol. 2014;19(3):441–53. doi:10.​1177/​1359105312473786​.PubMedCrossRef
133.
go back to reference Campbell R, Pound P, Pope C, Britten N, Pill R, Morgan M, et al. Evaluating meta-ethnography: a synthesis of qualitative research on lay experiences of diabetes and diabetes care. Soc Sci Med (1982). 2003;56(4):671–84.CrossRef Campbell R, Pound P, Pope C, Britten N, Pill R, Morgan M, et al. Evaluating meta-ethnography: a synthesis of qualitative research on lay experiences of diabetes and diabetes care. Soc Sci Med (1982). 2003;56(4):671–84.CrossRef
135.
go back to reference Cramer JA. A systematic review of adherence with medications for diabetes. Diabetes Care. 2004;27(5):1218–24.PubMedCrossRef Cramer JA. A systematic review of adherence with medications for diabetes. Diabetes Care. 2004;27(5):1218–24.PubMedCrossRef
137.
138.
go back to reference Ismail K, Winkley K, Rabe-Hesketh S. Systematic review and meta-analysis of randomised controlled trials of psychological interventions to improve glycaemic control in patients with type 2 diabetes. Lancet. 2004;363(9421):1589–97. doi:10.1016/s0140-6736(04)16202-8.PubMedCrossRef Ismail K, Winkley K, Rabe-Hesketh S. Systematic review and meta-analysis of randomised controlled trials of psychological interventions to improve glycaemic control in patients with type 2 diabetes. Lancet. 2004;363(9421):1589–97. doi:10.​1016/​s0140-6736(04)16202-8.PubMedCrossRef
139.
go back to reference Van Camp YP, Van Rompaey B, Elseviers MM. Nurse-led interventions to enhance adherence to chronic medication: systematic review and meta-analysis of randomised controlled trials. Eur J Clin Pharmacol. 2013;69(4):761–70. doi:10.1007/s00228-012-1419-y.PubMedCrossRef Van Camp YP, Van Rompaey B, Elseviers MM. Nurse-led interventions to enhance adherence to chronic medication: systematic review and meta-analysis of randomised controlled trials. Eur J Clin Pharmacol. 2013;69(4):761–70. doi:10.​1007/​s00228-012-1419-y.PubMedCrossRef
Metadata
Title
Type 2 diabetes patients’ and providers’ differing perspectives on medication nonadherence: a qualitative meta-synthesis
Authors
Francesca Brundisini
Meredith Vanstone
Danielle Hulan
Deirdre DeJean
Mita Giacomini
Publication date
01-06-2015
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2015
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/s12913-015-1174-8

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