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European Archives of Oto-Rhino-Laryngology

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04-08-2023 | Tympanoplasty | Review Article

Comparison of temporalis muscle fascia and cartilage grafts for primary type 1 tympanoplasty: a meta-analysis of randomized controlled trials

Authors: Ghassan Bin Lajdam, Rana A. Alahmadi, Mohammed Alhakami, Abdullah A. Ghaddaf, Ahmed S. Abdulhamid, Asma Alahmadi, Yassin Abdelsamad, Abdulrahman Hagr

Published in: European Archives of Oto-Rhino-Laryngology | Issue 12/2023

Abstract

Purpose

To compare the efficacy and safety of temporalis fascia (TF) with cartilage grafts for primary type 1 tympanoplasty in chronic otitis media (COM) patients.

Methods

Computerized search was performed in MEDLINE, Embase, and CENTRAL. Eligible for inclusion were randomized controlled trials (RCTs) comparing TF and cartilage grafts in individuals with non-cholesteatoma COM and intact ossicles requiring type 1 tympanoplasty. Primary outcomes were graft success and hearing improvement, measured by the air–bone gap (ABG) closure. The secondary outcome was the occurrence of complications. Standardized mean differences (SMD) and odds ratios (OR) with 95% confidence intervals were calculated.

Results

Eighteen RCTs that enrolled 1273 participants were found eligible. Data were reported at follow-up periods ranging from 6 weeks to 24 months. The pooled effect estimate revealed a higher and statistically significant graft success favoring cartilage grafts at 12 months (OR = 2.24, 95% CI 1.33–3.78) and 24 months (OR = 2.96, 95% CI 1.18–7.43). There was no significant difference between both grafts in post-operative ABG closure across all follow-up periods (6 weeks to 12 months).

Conclusions

Compared to TF, primary type 1 cartilage tympanoplasty offers better graft uptake rates and comparable postoperative hearing outcomes for COM patients.

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Title: Comparison of temporalis muscle fascia and cartilage grafts for primary type 1 tympanoplasty: a meta-analysis of randomized controlled trials
Authors: Ghassan Bin Lajdam
Rana A. Alahmadi
Mohammed Alhakami
Abdullah A. Ghaddaf
Ahmed S. Abdulhamid
Asma Alahmadi
Yassin Abdelsamad
Abdulrahman Hagr
Publication date: 04-08-2023
Publisher: Springer Berlin Heidelberg
Keywords: Tympanoplasty
Chronic Otitis Media
Published in: European Archives of Oto-Rhino-Laryngology / Issue 12/2023
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-023-08170-y

2024 ASCO Annual Meeting

Springer Medicine

Comparison of temporalis muscle fascia and cartilage grafts for primary type 1 tympanoplasty: a meta-analysis of randomized controlled trials

Abstract

Purpose

Methods

Results

Conclusions

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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