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Published in: Clinical Drug Investigation 5/2010

01-05-2010 | Case Report

Two Cases of Statin-Induced Rhabdomyolysis Associated with Mononeuropathy

Authors: Dr Gian Paolo Fadini, Enzo Manzato, Cristina Crepaldi, Saula de Kreutzenberg, Antonio Tiengo, Angelo Avogaro

Published in: Clinical Drug Investigation | Issue 5/2010

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Abstract

HMG-CoA reductase inhibitors (statins) are highly effective drugs for prevention of cardiovascular events in high-risk patients. Due to the widespread prescription of these agents, special attention should be given to their rare adverse effects when these may have severe outcomes. Here, we report two cases of localized rhabdomyolysis associated with mononeuropathy in patients taking statins and suggest possible explanations for this uncommon association. Close monitoring for myopathic/neuropathic events is warranted in high-risk patients with pre-existing neuropathies who are taking statins.
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Metadata
Title
Two Cases of Statin-Induced Rhabdomyolysis Associated with Mononeuropathy
Authors
Dr Gian Paolo Fadini
Enzo Manzato
Cristina Crepaldi
Saula de Kreutzenberg
Antonio Tiengo
Angelo Avogaro
Publication date
01-05-2010
Publisher
Springer International Publishing
Published in
Clinical Drug Investigation / Issue 5/2010
Print ISSN: 1173-2563
Electronic ISSN: 1179-1918
DOI
https://doi.org/10.2165/11535470-000000000-00000

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