Published in:
01-11-2006 | Rhinology
Two cases of malignant melanoma in turbinate and maxillary sinus
Authors:
Yoon-Seok Choi, Gil Soo Han, Jeong-Seok Choi, Tae Young Jang
Published in:
European Archives of Oto-Rhino-Laryngology
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Issue 11/2006
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Abstract
Malignant melanomas develop from malignant transformation of melanocytes that are present in the skin and mucosal linings throughout the body. The overall rate of mucosal melanoma is rare and malignant melanomas developing from turbinates or maxillary sinuses are extremely rare. Symptoms of nasal melanoma are generally nonspecific, and patients often fail to seek prompt medical attention. Diagnosis can be confirmed by the immunochemical profile of staining with anti-S100 and HMB-45 antibodies, even in the case of melanin-free pigment melanoma. The present study reports two cases of primary malignant melanoma in the turbinate and maxillary sinus.