Published in:
Open Access
01-12-2009 | Case report
Tuberous sclerosis with visceral leishmaniasis: a case report
Authors:
Krishna Pandey, Prabhat K Sinha, Vidyanand R Das, Nawin Kumar, Sanjiva Bimal, Rakesh B Verma, Neena Verma, Chandra S Lal, Roshan K Topno, NA Siddiqui, Dharmendra Singh, Pradeep Das
Published in:
Journal of Medical Case Reports
|
Issue 1/2009
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Abstract
Introduction
Visceral leishmaniasis, a tropical infectious disease, is a major public health problem in India. Tuberous sclerosis, a congenital neuro-ectodermosis, is an uncommon disease which requires life long treatment.
Case presentation
A 15-year-old Indian patient, presented to the outpatient department of our institute with a high-grade fever for two months, splenomegaly and a history of generalized tonic-clonic convulsions since childhood. The clinical and laboratory findings suggested visceral leishmaniasis with tuberous sclerosis. The patient was treated with miltefosine and antiepileptics.
Conclusion
The patient responded well and in a follow up six months after presentation, she was found free of visceral leishmaniasis and seizures. Diagnosis and treatment of this rare combination of diseases is difficult.