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01-02-2021 | Trigeminal Neuralgia | Original Article

Prognostic nomogram for microvascular decompression–treated trigeminal neuralgia

Authors: Wen-Bo Zhang, Ya-Ying Zeng, Bo-Wen Chang, Ling-Zhao Min, Qiu-Yang Sun, Bin Li, Bang-Bao Tao, Xiao-Qiang Wang

Published in: Neurosurgical Review | Issue 1/2021

Abstract

This study aimed to establish an effective prognostic nomogram for microvascular decompression (MVD)–treated trigeminal neuralgia (TN). The nomogram was based on a retrospective cohort study of 1054 patients with TN. During the period 2005–2014, 845 patients at our department treated TN with MVD and served as a development cohort. The predictive accuracy and discriminative ability of the nomogram were determined by concordance index (C-index) and calibration curve. The model was externally validated by 209 TN patients during 2014–2016. Multivariate cox analysis suggested that the patient’s age, atypical pain, vascular type, number of offending vessels, and second MVD were significant factors influencing the prognosis of MVD-treated TN. The C index of nomogram in the development cohort was 0.767 (95% CI, 0.739–0.794), and 0.749 (95% CI, 0.688–0.810) in the validation cohort. We developed and validated a nomogram to predict 3-year overall remission rate after MVD treatment of TN. The nomogram can be used in clinical trials to determine the likelihood of pain recurrence in TN patients treated with MVD for 3 years to aid in the comprehensive treatment of TN.

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Title: Prognostic nomogram for microvascular decompression–treated trigeminal neuralgia
Authors: Wen-Bo Zhang
Ya-Ying Zeng
Bo-Wen Chang
Ling-Zhao Min
Qiu-Yang Sun
Bin Li
Bang-Bao Tao
Xiao-Qiang Wang
Publication date: 01-02-2021
Publisher: Springer Berlin Heidelberg
Keyword: Trigeminal Neuralgia
Published in: Neurosurgical Review / Issue 1/2021
Print ISSN: 0344-5607
Electronic ISSN: 1437-2320
DOI: https://doi.org/10.1007/s10143-020-01251-0

At a glance: The STEP trials

Springer Medicine

Prognostic nomogram for microvascular decompression–treated trigeminal neuralgia

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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