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Published in: BMC Health Services Research 1/2009

Open Access 01-12-2009 | Research article

Trends in laboratory testing for diabetes in Ontario, Canada 1995–2005: A population-based study

Authors: Sarah E Wilson, Lorraine L Lipscombe, Laura C Rosella, Douglas G Manuel

Published in: BMC Health Services Research | Issue 1/2009

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Abstract

Background

There are concerns that testing for type 2 diabetes is low and many people with diabetes are not diagnosed. We sought to describe the rates of diabetes-related lab testing in Ontario from 1995–2005, among adults without diabetes, and to explore the extent to which the Canadian clinical practice guidelines for screening are being followed.

Methods

Descriptive counts of outpatient diabetes laboratory tests performed within Ontario's publicly funded, provincial health insurance program were recorded. The study population was Ontario residents, 20 years and older from 1995 to 2005 (9.3 million people in 2005). The Ontario Diabetes Database, a cumulative registry derived from administrative health records, was used to exclude people who had physician-diagnosed diabetes (n = 839,127 in 2005) from the primary analyses. Diabetes tests included serum blood glucose (SBG), hemoglobin A1c (HbA1c), and oral glucose tolerance tests (OGTT).

Results

In 2005, 37% of Ontario adults without pre-existing diabetes were tested with an SBG test, a 28% increase from 1995. The age-adjusted proportion of adults without diabetes undergoing a HbA1c test increased from 1.7% in 1995 to 6.0% in 2005. In 2005, a similar number of HbA1c tests were performed for individuals with diabetes (483,746) and without diabetes (496,616) despite large differences in the two groups' denominators. Less than 1% of Ontarians underwent OGTT testing in any year between 1995–2005. Nearly two-thirds of adults age 40 years and over had an SBG test over a 3-year period (April 1, 2002–March 31, 2005), in accordance with the Canadian Diabetes Association recommendations.

Conclusion

Diabetes testing is common and has increased over the last ten years. Despite its absence in Canada's diabetes screening recommendations, HbA1c testing among individuals without diabetes is increasing rapidly, and OGTT, which is recommended, is rarely performed.
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Literature
1.
go back to reference King H, Aubert RE, Herman WH: Global burden of diabetes, 1995–2025: prevalence, numerical estimates, and projections. Diabetes Care. 1998, 21: 1414-31. 10.2337/diacare.21.9.1414.CrossRefPubMed King H, Aubert RE, Herman WH: Global burden of diabetes, 1995–2025: prevalence, numerical estimates, and projections. Diabetes Care. 1998, 21: 1414-31. 10.2337/diacare.21.9.1414.CrossRefPubMed
2.
go back to reference Wild S, Roglic G, Green A, Sicree R, King H: Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care. 2004, 27: 1047-53. 10.2337/diacare.27.5.1047.CrossRefPubMed Wild S, Roglic G, Green A, Sicree R, King H: Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care. 2004, 27: 1047-53. 10.2337/diacare.27.5.1047.CrossRefPubMed
3.
go back to reference Lipscombe L, Hux JE: Trends in diabetes prevalence, incidence, and mortality in Ontario, Canada 1995–2005: a population-based study. Lancet. 2007, 369: 750-756. 10.1016/S0140-6736(07)60361-4.CrossRefPubMed Lipscombe L, Hux JE: Trends in diabetes prevalence, incidence, and mortality in Ontario, Canada 1995–2005: a population-based study. Lancet. 2007, 369: 750-756. 10.1016/S0140-6736(07)60361-4.CrossRefPubMed
4.
go back to reference Flegal KM, Carroll MD, Ogden CL, Johnson CL: Prevalence and trends in obesity among US adults, 1999–2000. JAMA. 2002, 288: 1723-1727. 10.1001/jama.288.14.1723.CrossRefPubMed Flegal KM, Carroll MD, Ogden CL, Johnson CL: Prevalence and trends in obesity among US adults, 1999–2000. JAMA. 2002, 288: 1723-1727. 10.1001/jama.288.14.1723.CrossRefPubMed
5.
go back to reference Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM: Prevalence of overweight and obesity in the United States, 1999–2004. JAMA. 2006, 295: 1549-1555. 10.1001/jama.295.13.1549.CrossRefPubMed Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM: Prevalence of overweight and obesity in the United States, 1999–2004. JAMA. 2006, 295: 1549-1555. 10.1001/jama.295.13.1549.CrossRefPubMed
7.
go back to reference Rennie KL, Jebb SA: Prevalence of obesity in Great Britain. Obes Rev. 2005, 6: 11-12. 10.1111/j.1467-789X.2005.00164.x.CrossRefPubMed Rennie KL, Jebb SA: Prevalence of obesity in Great Britain. Obes Rev. 2005, 6: 11-12. 10.1111/j.1467-789X.2005.00164.x.CrossRefPubMed
8.
go back to reference Cameron AJ, Welborn TA, Zimmet PZ, Dunstan DW, Owen N, Salmon J, Dalton M, Jolley D, Shaw J: Overweight and obesity in Australia: the 1999–2000 Australian diabetes, obesity and lifestyle study (AusDiab). Med J Aust. 2003, 178: 427-432.PubMed Cameron AJ, Welborn TA, Zimmet PZ, Dunstan DW, Owen N, Salmon J, Dalton M, Jolley D, Shaw J: Overweight and obesity in Australia: the 1999–2000 Australian diabetes, obesity and lifestyle study (AusDiab). Med J Aust. 2003, 178: 427-432.PubMed
9.
go back to reference Cowie CC, Rust KF, Byrd-Holt DD, Eberhardt MS, Flegal KM, Engelgau MM, Saydah SH, Williams DE, Geiss LS, Gregg EW: Prevalence of Diabetes and Impaired Fasting Glucose in Adults in the US Population. National Health and Nutrition Examination Survey 1999–2002. Diabetes Care. 2006, 29: 1263-1268. 10.2337/dc06-0062.CrossRefPubMed Cowie CC, Rust KF, Byrd-Holt DD, Eberhardt MS, Flegal KM, Engelgau MM, Saydah SH, Williams DE, Geiss LS, Gregg EW: Prevalence of Diabetes and Impaired Fasting Glucose in Adults in the US Population. National Health and Nutrition Examination Survey 1999–2002. Diabetes Care. 2006, 29: 1263-1268. 10.2337/dc06-0062.CrossRefPubMed
10.
go back to reference Harris MI, Flegal KM, Cowie CC, Eberhardt MS, Goldstein DE, Little RR, Wiedmeyer HM, Byrd-Holt DD: Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988–1994. Diabetes Care. 1998, 21: 518-24. 10.2337/diacare.21.4.518.CrossRefPubMed Harris MI, Flegal KM, Cowie CC, Eberhardt MS, Goldstein DE, Little RR, Wiedmeyer HM, Byrd-Holt DD: Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988–1994. Diabetes Care. 1998, 21: 518-24. 10.2337/diacare.21.4.518.CrossRefPubMed
12.
go back to reference Leiter LA, Barr A, Bélanger A, Lubin S, Ross SA, Tildesley HD, Fontaine N: Diabetes screening in Canada (DIASCAN) Study. Diabetes Care. 2001, 24: 1038-1043. 10.2337/diacare.24.6.1038.CrossRefPubMed Leiter LA, Barr A, Bélanger A, Lubin S, Ross SA, Tildesley HD, Fontaine N: Diabetes screening in Canada (DIASCAN) Study. Diabetes Care. 2001, 24: 1038-1043. 10.2337/diacare.24.6.1038.CrossRefPubMed
13.
go back to reference Harris MI, Klein R, Welborn TA, Knuiman MW: Onset of NIDDM occurs at least 4–7 yr before clinical diagnosis. Diabetes Care. 1992, 15: 815-819. 10.2337/diacare.15.7.815.CrossRefPubMed Harris MI, Klein R, Welborn TA, Knuiman MW: Onset of NIDDM occurs at least 4–7 yr before clinical diagnosis. Diabetes Care. 1992, 15: 815-819. 10.2337/diacare.15.7.815.CrossRefPubMed
14.
go back to reference Meltzer S, Lawrence L, Daneman D, Gerstein HC, Lau D, Ludwig S, Yale J-F, Zinman B, Lillie D, Steering and Expert Committees: 1998 clinical practice guidelines for the management of diabetes in Canada. CMAJ. 1998, S1-29. Suppl Meltzer S, Lawrence L, Daneman D, Gerstein HC, Lau D, Ludwig S, Yale J-F, Zinman B, Lillie D, Steering and Expert Committees: 1998 clinical practice guidelines for the management of diabetes in Canada. CMAJ. 1998, S1-29. Suppl
15.
go back to reference Canadian Diabetes Association Clinical Practice Guidelines Expert Committee: Canadian Diabetes Association 2003 clinical practice guidelines for the prevention and management of diabetes in Canada. Can J Diabetes. 2003, 27: S10-S13. Canadian Diabetes Association Clinical Practice Guidelines Expert Committee: Canadian Diabetes Association 2003 clinical practice guidelines for the prevention and management of diabetes in Canada. Can J Diabetes. 2003, 27: S10-S13.
16.
go back to reference Expert Committee of the Canadian Diabetes Advisory Board: Clinical practice guidelines for treatment of diabetes mellitus. CMAJ. 1992, 147: 697-712. Expert Committee of the Canadian Diabetes Advisory Board: Clinical practice guidelines for treatment of diabetes mellitus. CMAJ. 1992, 147: 697-712.
17.
go back to reference Feig DS, Palda VA, Lipscombe L, the Canadian Task Force on Preventive Health Care: Screening for type 2 diabetes mellitus to prevent vascular complications: updated recommendations from the Canadian Task Force on Preventive Health Care. CMAJ. 2005, 172: 177-80.CrossRefPubMedPubMedCentral Feig DS, Palda VA, Lipscombe L, the Canadian Task Force on Preventive Health Care: Screening for type 2 diabetes mellitus to prevent vascular complications: updated recommendations from the Canadian Task Force on Preventive Health Care. CMAJ. 2005, 172: 177-80.CrossRefPubMedPubMedCentral
18.
go back to reference Hux JE, Ivis F, Flintoft V, Bica A: Diabetes in Ontario. Determination of prevalence and incidence using a validated administrative data algorithm. Diabetes Care. 2002, 25: 512-516. 10.2337/diacare.25.3.512.CrossRefPubMed Hux JE, Ivis F, Flintoft V, Bica A: Diabetes in Ontario. Determination of prevalence and incidence using a validated administrative data algorithm. Diabetes Care. 2002, 25: 512-516. 10.2337/diacare.25.3.512.CrossRefPubMed
20.
go back to reference Chiarelli AM, Halapy E, Nadalin V, Shumak R, O'Malley F, Mai V: Performance measures from 10 years of breast screening in the Ontario Breast Screening Program, 1990/91 to 2000. Eur J Cancer Prev. 2006, 15: 34-42. 10.1097/01.cej.0000195713.02567.36.CrossRefPubMed Chiarelli AM, Halapy E, Nadalin V, Shumak R, O'Malley F, Mai V: Performance measures from 10 years of breast screening in the Ontario Breast Screening Program, 1990/91 to 2000. Eur J Cancer Prev. 2006, 15: 34-42. 10.1097/01.cej.0000195713.02567.36.CrossRefPubMed
22.
go back to reference Lofters A, Glazier RH, Agha MM, Creatore MI, Moineddin R: Inadequacy of cervical cancer screening among urban recent immigrants: A population-based study of physician and laboratory claims in Toronto, Canada. Prev Med. 2007, 44: 536-542. 10.1016/j.ypmed.2007.02.019.CrossRefPubMed Lofters A, Glazier RH, Agha MM, Creatore MI, Moineddin R: Inadequacy of cervical cancer screening among urban recent immigrants: A population-based study of physician and laboratory claims in Toronto, Canada. Prev Med. 2007, 44: 536-542. 10.1016/j.ypmed.2007.02.019.CrossRefPubMed
23.
go back to reference Fehringer G, Howlett R, Cotterchio M, Klar N, Majpruz-Moat V, Mai V: Comparison of papanicolaou (Pap) test rates across Ontario and factors associated with cervical screening. Can J Public Health. 2005, 96: 140-4.PubMed Fehringer G, Howlett R, Cotterchio M, Klar N, Majpruz-Moat V, Mai V: Comparison of papanicolaou (Pap) test rates across Ontario and factors associated with cervical screening. Can J Public Health. 2005, 96: 140-4.PubMed
24.
go back to reference Lyon AW, Larsen ET, Edwards AL: The impact of new guidelines for glucose tolerance testing on clinical practice and laboratory services. CMAJ. 2004, 171: 1067-1069.CrossRefPubMedPubMedCentral Lyon AW, Larsen ET, Edwards AL: The impact of new guidelines for glucose tolerance testing on clinical practice and laboratory services. CMAJ. 2004, 171: 1067-1069.CrossRefPubMedPubMedCentral
25.
go back to reference Janssen PGH, Gorter KJ, Stolk RP, Rutten GEHM: Low yield of population-based screening for Type 2 diabetes in the Netherlands: the ADDITION Netherlands study. Family Practice. 2007, 24: 555-561. 10.1093/fampra/cmm052.CrossRefPubMed Janssen PGH, Gorter KJ, Stolk RP, Rutten GEHM: Low yield of population-based screening for Type 2 diabetes in the Netherlands: the ADDITION Netherlands study. Family Practice. 2007, 24: 555-561. 10.1093/fampra/cmm052.CrossRefPubMed
26.
go back to reference DECODE Study Group on behalf of the European Diabetes Epidemiology Study Group: Will new diagnostic criteria for diabetes mellitus change phenotype of patients with diabetes? Reanalysis of European epidemiological data. BMJ. 1998, 317: 371-375.CrossRefPubMedCentral DECODE Study Group on behalf of the European Diabetes Epidemiology Study Group: Will new diagnostic criteria for diabetes mellitus change phenotype of patients with diabetes? Reanalysis of European epidemiological data. BMJ. 1998, 317: 371-375.CrossRefPubMedCentral
27.
go back to reference The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus: Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care. 1997, 20: 1183-1197.CrossRef The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus: Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care. 1997, 20: 1183-1197.CrossRef
28.
go back to reference Barrett-Connor E, Ferrara A: Isolated postchallenge hyperglycemia and the risk of fatal cardiovascular disease in older women and men. Diabetes Care. 1998, 21: 1236-1239. 10.2337/diacare.21.8.1236.CrossRefPubMed Barrett-Connor E, Ferrara A: Isolated postchallenge hyperglycemia and the risk of fatal cardiovascular disease in older women and men. Diabetes Care. 1998, 21: 1236-1239. 10.2337/diacare.21.8.1236.CrossRefPubMed
29.
go back to reference The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus: Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care. 2003, 26: 3160-3167. 10.2337/diacare.26.11.3160.CrossRef The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus: Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care. 2003, 26: 3160-3167. 10.2337/diacare.26.11.3160.CrossRef
30.
go back to reference Bennett CM, Guo M, Dharmage SC: HbA1c as a screening tool for detection of Type 2 diabetes: a systematic review. Diabet Med. 2007, 24: 333-343. 10.1111/j.1464-5491.2007.02106.x.CrossRefPubMed Bennett CM, Guo M, Dharmage SC: HbA1c as a screening tool for detection of Type 2 diabetes: a systematic review. Diabet Med. 2007, 24: 333-343. 10.1111/j.1464-5491.2007.02106.x.CrossRefPubMed
31.
go back to reference Kim KS, Kim SK, Lee YK, Park SW, Cho YW: Diagnostic value of glycated haemoglobin (HbA1c) for the early detection of diabetes in high-risk subjects. Diabet Med. 2008, 25: 997-1000. 10.1111/j.1464-5491.2008.02489.x.CrossRefPubMed Kim KS, Kim SK, Lee YK, Park SW, Cho YW: Diagnostic value of glycated haemoglobin (HbA1c) for the early detection of diabetes in high-risk subjects. Diabet Med. 2008, 25: 997-1000. 10.1111/j.1464-5491.2008.02489.x.CrossRefPubMed
Metadata
Title
Trends in laboratory testing for diabetes in Ontario, Canada 1995–2005: A population-based study
Authors
Sarah E Wilson
Lorraine L Lipscombe
Laura C Rosella
Douglas G Manuel
Publication date
01-12-2009
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2009
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/1472-6963-9-41

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