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Current Treatment Options in Neurology
Published in: Current Treatment Options in Neurology 8/2015

01-08-2015 | Dementia (E McDade, Section Editor)

Treatment of Primary Progressive Aphasia

Authors: Donna C. Tippett, MPH, MA, Argye E. Hillis, MD, MA, Kyrana Tsapkini, PhD

Published in: Current Treatment Options in Neurology | Issue 8/2015

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Opinion statement

Primary progressive aphasia (PPA) is a neurodegenerative disease that primarily affects language functions and often begins in the fifth or sixth decade of life. The devastating effects on work and home life call for the investigation of treatment alternatives. In this paper, we present a review of the literature on treatment approaches for this neurodegenerative disease. We also present new data from two intervention studies we have conducted, a behavioral one and a neuromodulatory one using transcranial direct current stimulation (tDCS) combined with written production intervention. We show that speech-language intervention improves language outcomes in individuals with PPA, and especially in the short term, tDCS augments generalization and maintenance of positive language outcomes. We also outline current issues and challenges in intervention approaches in PPA.
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Metadata
Title
Treatment of Primary Progressive Aphasia
Authors
Donna C. Tippett, MPH, MA
Argye E. Hillis, MD, MA
Kyrana Tsapkini, PhD
Publication date
01-08-2015
Publisher
Springer US
Published in
Current Treatment Options in Neurology / Issue 8/2015
Print ISSN: 1092-8480
Electronic ISSN: 1534-3138
DOI
https://doi.org/10.1007/s11940-015-0362-5

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