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Published in: World Journal of Surgery 2/2014

01-02-2014

Trauma Whipple: Do or Don’t After Severe Pancreaticoduodenal Injuries? An Analysis of the National Trauma Data Bank (NTDB)

Authors: Gwendolyn M. van der Wilden, D. Dante Yeh, John O. Hwabejire, Eric N. Klein, Peter J. Fagenholz, David R. King, Marc A. de Moya, Yuchiao Chang, George C. Velmahos

Published in: World Journal of Surgery | Issue 2/2014

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Abstract

Background

Pancreaticoduodenectomy for trauma (PDT) is a rare procedure, reserved for severe pancreaticoduodenal injuries. Using the National Trauma Data Bank (NTDB), our aim was to compare outcomes of PDT patients to similarly injured patients who did not undergo a PDT.

Methods

Patients with pancreatic or duodenal injuries treated with PDT (ICD-9-CM 52.7) were identified in the NTDB 2008–2010 Research Data Sets. We excluded those who underwent delayed PDT (>4 days). The PDT group (n = 39) was compared to patients with severe combined pancreaticoduodenal injuries (grade 4 or 5) who did not undergo PDT (non-PDT group, n = 38). Patients who died in the emergency department or did not undergo a laparotomy were excluded. Our primary outcome was death. Secondary outcomes were intensive care unit length of stay (LOS), hospital LOS, and total ventilator days. A multivariate model was used to determine predictors of in-hospital mortality within each group and in the overall cohort.

Results

The non-PDT group had a significantly lower systolic blood pressure and Glasgow Coma Scale values at baseline and more severe duodenal, pancreatic, and liver injuries. There were no significant differences in outcomes between the two groups. The Injury Severity Score was the only independent predictor of mortality among PDT patients [odds ratio (OR) 1.12, 95 % confidence interval (CI) 1.01–1.24] and in the entire cohort (OR 1.06, 95 % CI 1.01–1.12). The operative technique did not influence any of the outcomes.

Conclusions

Compared to non-PDT, PDT did not result in improved outcomes despite a lower physiologic burden among PDT patients. More conservative procedures for high-grade injuries of the pancreaticoduodenal complex may be appropriate.
Literature
1.
go back to reference Whipple AO, Parsons WB, Mullins CR (1935) Treatment of carcinoma of the ampulla of Vater. Ann Surg 102:763–779PubMedCrossRef Whipple AO, Parsons WB, Mullins CR (1935) Treatment of carcinoma of the ampulla of Vater. Ann Surg 102:763–779PubMedCrossRef
2.
go back to reference Wray CJ, Ahmad SA, Matthews JB et al (2005) Surgery for pancreatic cancer: recent controversies and current practice. Gastroenterology 128:1626–1641PubMedCrossRef Wray CJ, Ahmad SA, Matthews JB et al (2005) Surgery for pancreatic cancer: recent controversies and current practice. Gastroenterology 128:1626–1641PubMedCrossRef
3.
go back to reference Yeo CJ, Cameron JL, Sohn TA et al (1997) Six hundred fifty consecutive pancreaticoduodenectomies in the 1990s: pathology, complications, and outcomes. Ann Surg 226:248–257PubMedCrossRef Yeo CJ, Cameron JL, Sohn TA et al (1997) Six hundred fifty consecutive pancreaticoduodenectomies in the 1990s: pathology, complications, and outcomes. Ann Surg 226:248–257PubMedCrossRef
4.
go back to reference Foley WJ, Gaines RD, Fry WJ (1969) Pancreaticoduodenectomy for severe trauma to the head of the pancreas and the associated structures: report of three cases. Ann Surg 170:759–765PubMedCrossRef Foley WJ, Gaines RD, Fry WJ (1969) Pancreaticoduodenectomy for severe trauma to the head of the pancreas and the associated structures: report of three cases. Ann Surg 170:759–765PubMedCrossRef
5.
go back to reference Thal AP, Wilson RF (1964) A pattern of severe blunt trauma to the region of the pancreas. Surg Gynecol Obstet 119:773–778PubMed Thal AP, Wilson RF (1964) A pattern of severe blunt trauma to the region of the pancreas. Surg Gynecol Obstet 119:773–778PubMed
6.
go back to reference Asensio JA, Feliciano DV, Britt LD et al (1993) Management of duodenal injuries. Curr Probl Surg 30:1023–1093PubMedCrossRef Asensio JA, Feliciano DV, Britt LD et al (1993) Management of duodenal injuries. Curr Probl Surg 30:1023–1093PubMedCrossRef
7.
go back to reference Fabian TC, Bee TK (2008) Liver and biliary tract. In: Feliciano DV, Mattox KL, Moore EE (eds) Trauma, 6th edn. McGraw-Hill, New York Fabian TC, Bee TK (2008) Liver and biliary tract. In: Feliciano DV, Mattox KL, Moore EE (eds) Trauma, 6th edn. McGraw-Hill, New York
8.
go back to reference Feliciano DV, Martin TD, Cruse PA et al (1987) Management of combined pancreatoduodenal injuries. Ann Surg 205:673–680PubMedCrossRef Feliciano DV, Martin TD, Cruse PA et al (1987) Management of combined pancreatoduodenal injuries. Ann Surg 205:673–680PubMedCrossRef
9.
go back to reference Graham JM, Mattox KL, Vaughan GD et al (1979) Combined pancreatoduodenal injuries. J Trauma 19:340–346PubMedCrossRef Graham JM, Mattox KL, Vaughan GD et al (1979) Combined pancreatoduodenal injuries. J Trauma 19:340–346PubMedCrossRef
10.
go back to reference Lopez PP, Benjamin R, Cockburn M et al (2005) Recent trends in the management of combined pancreatoduodenal injuries. Am Surg 71:847–852PubMed Lopez PP, Benjamin R, Cockburn M et al (2005) Recent trends in the management of combined pancreatoduodenal injuries. Am Surg 71:847–852PubMed
11.
go back to reference Moore EE, Cogbill TH, Malangoni MA et al (1990) Organ injury scaling. II. Pancreas, duodenum, small bowel, colon, and rectum. J Trauma 30:1427–1429PubMedCrossRef Moore EE, Cogbill TH, Malangoni MA et al (1990) Organ injury scaling. II. Pancreas, duodenum, small bowel, colon, and rectum. J Trauma 30:1427–1429PubMedCrossRef
12.
go back to reference Asensio JA, Petrone P, Roldan G et al (2003) Pancreaticoduodenectomy: a rare procedure for the management of complex pancreaticoduodenal injuries. J Am Coll Surg 197:937–942PubMedCrossRef Asensio JA, Petrone P, Roldan G et al (2003) Pancreaticoduodenectomy: a rare procedure for the management of complex pancreaticoduodenal injuries. J Am Coll Surg 197:937–942PubMedCrossRef
13.
go back to reference Gentilello LM, Cortes V, Buechter KJ et al (1991) Whipple procedure for trauma: is duct ligation a safe alternative to pancreaticojejunostomy? J Trauma 31:661–667PubMedCrossRef Gentilello LM, Cortes V, Buechter KJ et al (1991) Whipple procedure for trauma: is duct ligation a safe alternative to pancreaticojejunostomy? J Trauma 31:661–667PubMedCrossRef
14.
go back to reference Gupta V, Wig JD, Garg H (2008) Trauma pancreaticoduodenectomy for complex pancreaticoduodenal injury: delayed reconstruction. JOP 9:618–623PubMed Gupta V, Wig JD, Garg H (2008) Trauma pancreaticoduodenectomy for complex pancreaticoduodenal injury: delayed reconstruction. JOP 9:618–623PubMed
15.
go back to reference McKone TK, Bursch LR, Scholten DJ (1988) Pancreaticoduodenectomy for trauma: a life-saving procedure. Am Surg 54:361–364PubMed McKone TK, Bursch LR, Scholten DJ (1988) Pancreaticoduodenectomy for trauma: a life-saving procedure. Am Surg 54:361–364PubMed
16.
go back to reference Oreskovich MR, Carrico CJ (1984) Pancreaticoduodenectomy for trauma: a viable option? Am J Surg 147:618–623PubMedCrossRef Oreskovich MR, Carrico CJ (1984) Pancreaticoduodenectomy for trauma: a viable option? Am J Surg 147:618–623PubMedCrossRef
17.
go back to reference Yellin AE, Rosoff L Sr (1975) Pancreatoduodenectomy for combined pancreatoduodenal injuries. Arch Surg 110:1177–1183PubMedCrossRef Yellin AE, Rosoff L Sr (1975) Pancreatoduodenectomy for combined pancreatoduodenal injuries. Arch Surg 110:1177–1183PubMedCrossRef
18.
go back to reference Asensio JA, Demetriades D, Hanpeter DE et al (1999) Management of pancreatic injuries. Curr Probl Surg 36:325–419PubMedCrossRef Asensio JA, Demetriades D, Hanpeter DE et al (1999) Management of pancreatic injuries. Curr Probl Surg 36:325–419PubMedCrossRef
19.
go back to reference Mansour MA, Moore JB, Moore EE et al (1989) Conservative management of combined pancreatoduodenal injuries. Am J Surg 158:531–535PubMedCrossRef Mansour MA, Moore JB, Moore EE et al (1989) Conservative management of combined pancreatoduodenal injuries. Am J Surg 158:531–535PubMedCrossRef
21.
go back to reference Subramanian A, Dente CJ, Feliciano DV (2007) The management of pancreatic trauma in the modern era. Surg Clin North Am 87:1515–1532PubMedCrossRef Subramanian A, Dente CJ, Feliciano DV (2007) The management of pancreatic trauma in the modern era. Surg Clin North Am 87:1515–1532PubMedCrossRef
22.
go back to reference Feliciano D (1989) Abdominal trauma. In: Schwartz SI, Ellis H (eds) Maingot’s abdominal operations, 9th edn. Appleton & Lange, East Norwalk Feliciano D (1989) Abdominal trauma. In: Schwartz SI, Ellis H (eds) Maingot’s abdominal operations, 9th edn. Appleton & Lange, East Norwalk
23.
go back to reference Birkmeyer JD, Stukel TA, Siewers AE et al (2003) Surgeon volume and operative mortality in the United States. N Engl J Med 349:2117–2127PubMedCrossRef Birkmeyer JD, Stukel TA, Siewers AE et al (2003) Surgeon volume and operative mortality in the United States. N Engl J Med 349:2117–2127PubMedCrossRef
24.
go back to reference Eppsteiner RW, Csikesz NG, McPhee JT et al (2009) Surgeon volume impacts hospital mortality for pancreatic resection. Ann Surg 249:635–640PubMedCrossRef Eppsteiner RW, Csikesz NG, McPhee JT et al (2009) Surgeon volume impacts hospital mortality for pancreatic resection. Ann Surg 249:635–640PubMedCrossRef
25.
go back to reference Nathan H, Cameron JL, Choti MA et al (2009) The volume-outcomes effect in hepato-pancreato-biliary surgery: hospital versus surgeon contributions and specificity of the relationship. J Am Coll Surg 208:528–538PubMedCrossRef Nathan H, Cameron JL, Choti MA et al (2009) The volume-outcomes effect in hepato-pancreato-biliary surgery: hospital versus surgeon contributions and specificity of the relationship. J Am Coll Surg 208:528–538PubMedCrossRef
26.
go back to reference Schmidt CM, Turrini O, Parikh P et al (2010) Effect of hospital volume, surgeon experience, and surgeon volume on patient outcomes after pancreaticoduodenectomy: a single-institution experience. Arch Surg 145:634–640PubMedCrossRef Schmidt CM, Turrini O, Parikh P et al (2010) Effect of hospital volume, surgeon experience, and surgeon volume on patient outcomes after pancreaticoduodenectomy: a single-institution experience. Arch Surg 145:634–640PubMedCrossRef
27.
go back to reference The pancreas and duodenum. In: Jacobs LM, Luk SS (eds) Advanced trauma operative management: surgical strategies for penetrating trauma, 2nd edn (2010). Ciné-Med Publishing, Woodbury The pancreas and duodenum. In: Jacobs LM, Luk SS (eds) Advanced trauma operative management: surgical strategies for penetrating trauma, 2nd edn (2010). Ciné-Med Publishing, Woodbury
28.
go back to reference Velmahos GC, Tabbara M, Gross R et al (2009) Blunt pancreatoduodenal injury: a multicenter study of the Research Consortium of New England Centers for Trauma (ReCONECT). Arch Surg 144:413–419PubMedCrossRef Velmahos GC, Tabbara M, Gross R et al (2009) Blunt pancreatoduodenal injury: a multicenter study of the Research Consortium of New England Centers for Trauma (ReCONECT). Arch Surg 144:413–419PubMedCrossRef
29.
go back to reference Duchesne JC, Schmieg R, Islam S et al (2008) Selective nonoperative management of low-grade blunt pancreatic injury: are we there yet? J Trauma 65:49–53PubMedCrossRef Duchesne JC, Schmieg R, Islam S et al (2008) Selective nonoperative management of low-grade blunt pancreatic injury: are we there yet? J Trauma 65:49–53PubMedCrossRef
30.
go back to reference Haider AH, Saleem T, Leow JJ et al (2012) Influence of the National Trauma Data Bank on the study of trauma outcomes: is it time to set research best practices to further enhance its impact? J Am Coll Surg 214:756–768PubMedCentralPubMedCrossRef Haider AH, Saleem T, Leow JJ et al (2012) Influence of the National Trauma Data Bank on the study of trauma outcomes: is it time to set research best practices to further enhance its impact? J Am Coll Surg 214:756–768PubMedCentralPubMedCrossRef
Metadata
Title
Trauma Whipple: Do or Don’t After Severe Pancreaticoduodenal Injuries? An Analysis of the National Trauma Data Bank (NTDB)
Authors
Gwendolyn M. van der Wilden
D. Dante Yeh
John O. Hwabejire
Eric N. Klein
Peter J. Fagenholz
David R. King
Marc A. de Moya
Yuchiao Chang
George C. Velmahos
Publication date
01-02-2014
Publisher
Springer US
Published in
World Journal of Surgery / Issue 2/2014
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-013-2257-5

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