Published in:
01-03-2012 | Editorial
Transpulmonary pressure as a surrogate of plateau pressure for lung protective strategy: not perfect but more physiologic
Authors:
Jean-Christophe M. Richard, John J. Marini
Published in:
Intensive Care Medicine
|
Issue 3/2012
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Excerpt
During the last pandemic, experience in the management of the most severely affected patients with influenza A (H1N1)-related acute respiratory distress syndrome (ARDS) included increased use of extracorporeal membrane oxygenation (ECMO) [
1,
2]. Growing interest in this technique has been spurred by the results of a large cohort study in which transfer to an ECMO center was associated with lower hospital mortality than matched non-ECMO-referred patients [
3]. To date, it has been difficult to establish recommendations for ECMO referral, since neither the type of patients who benefit from this technique nor the exact timing of the switch from conventional treatment to ECMO have been systematically investigated [
4]. …