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Intensive Care Medicine
Published in: Intensive Care Medicine 7/2010

01-07-2010 | Correspondence

Transfusion-associated graft-versus-host disease presenting as severe high-volume diarrhoea in a patient with Goodpasture’s syndrome

Authors: Karin Amrein, Ursula Posch, Cord Langner, Gregor Gorkiewicz, Christoph Högenauer

Published in: Intensive Care Medicine | Issue 7/2010

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Excerpt

We report a formerly immunocompetent patient with Goodpasture’s syndrome who developed therapy-resistant, high-volume watery diarrhoea caused by transfusion-associated graft-versus-host disease (TA-GVHD) after transfusion of red blood cells. …
Literature
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Agbaht K, Altintas ND, Topeli A, Gokoz O, Ozcebe O (2007) Transfusion-associated graft-versus-host disease in immunocompetent patients: case series and review of the literature. Transfusion 47:1405–1411CrossRefPubMed
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BCSH Blood Transfusion Task Force (1996) Guidelines on gamma irradiation of blood components for the prevention of transfusion-associated graft-versus-host disease. Transfus Med 6:261–271CrossRef
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Leitman SF, Tisdale JF, Bolan CD, Popovsky MA, Klippel JH, Balow JE, Boumpas DT, Illei GG (2003) Transfusion-associated GVHD after fludarabine therapy in a patient with systemic lupus erythematosus. Transfusion 43:1667–1671CrossRefPubMed
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Illei GG, Yarboro CH, Kuroiwa T, Schlimgen R, Austin HA, Tisdale JF, Chitkara P, Fleisher T, Klippel JH, Balow JE, Boumpas DT (2007) Long-term effects of combination treatment with fludarabine and low-dose pulse cyclophosphamide in patients with lupus nephritis. Rheumatology (Oxford) 46:952–956CrossRef
Metadata
Title
Transfusion-associated graft-versus-host disease presenting as severe high-volume diarrhoea in a patient with Goodpasture’s syndrome
Authors
Karin Amrein
Ursula Posch
Cord Langner
Gregor Gorkiewicz
Christoph Högenauer
Publication date
01-07-2010
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 7/2010
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-010-1881-x

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