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Published in: Journal of Cardiothoracic Surgery 1/2021

Open Access 01-12-2021 | Transesophageal Echocardiography | Case report

A potential misdiagnosis in the COVID-19 pandemic era: a case report of superimposed thrombosis or tumor recurrence

Authors: Arezou Zoroufian, Reza Mohseni-Badalabadi, Mehrdad Mahalleh, Seyyed Mojtaba Ghorashi, Sharam Momtahen, Negar Omidi

Published in: Journal of Cardiothoracic Surgery | Issue 1/2021

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Abstract

Background

The clinical manifestations of coronavirus disease 2019 (COVID-19) overlap with those of other disorders, especially cardiovascular disease.

Case presentation

We herein describe a 58-year-old woman who presented with syncopal episodes and dyspnea on exertion with a left atrial (LA) mass, scheduled for surgical removal and mitral valve replacement. Nearly 3 months later, the patient developed dyspnea, fever, and a sore throat, resulting in hospital admission with suspected COVID-19. During the diagnostic evaluation, a larger LA mass was detected. The mass seemed to be a COVID-19–induced organized thrombus with prosthetic mitral valve malfunction. Resection was, therefore, planned. An immunohistochemistry study revealed a liposarcoma.

Conclusions

The unusual early recurrence of liposarcomas and the misdiagnosis with COVID-19–induced thrombosis are the hallmark of the present case.
Literature
1.
go back to reference Shafi AM, Shaikh SA, Shirke MM, Iddawela S, Harky A. Cardiac manifestations in COVID-19 patients—A systematic review. J Card Surg. 2020;35(8):1988–2008.CrossRef Shafi AM, Shaikh SA, Shirke MM, Iddawela S, Harky A. Cardiac manifestations in COVID-19 patients—A systematic review. J Card Surg. 2020;35(8):1988–2008.CrossRef
2.
go back to reference Bansal M. Cardiovascular disease and COVID-19. Diabetes Metab Syndrome Clin Res Rev. 2020;14:257.CrossRef Bansal M. Cardiovascular disease and COVID-19. Diabetes Metab Syndrome Clin Res Rev. 2020;14:257.CrossRef
3.
go back to reference Hoffmeier A, Sindermann JR, Scheld HH, Martens S. Cardiac tumors–diagnosis and surgical treatment. Deutsches Arzteblatt Int. 2014;111(12):205–11. Hoffmeier A, Sindermann JR, Scheld HH, Martens S. Cardiac tumors–diagnosis and surgical treatment. Deutsches Arzteblatt Int. 2014;111(12):205–11.
4.
go back to reference Ramlawi B, Leja MJ, Abu Saleh WK, Al Jabbari O, Benjamin R, Ravi V, Shapira OM, Blackmon SH, Bruckner BA, Reardon MJ. Surgical treatment of primary cardiac sarcomas: review of a single-institution experience. Ann Thorac Surg. 2016;101(2):698–702.CrossRef Ramlawi B, Leja MJ, Abu Saleh WK, Al Jabbari O, Benjamin R, Ravi V, Shapira OM, Blackmon SH, Bruckner BA, Reardon MJ. Surgical treatment of primary cardiac sarcomas: review of a single-institution experience. Ann Thorac Surg. 2016;101(2):698–702.CrossRef
5.
go back to reference Look Hong NJ, Pandalai PK, Hornick JL, Shekar PS, Harmon DC, Chen YL, Butrynski JE, Baldini EH, Raut CP. Cardiac angiosarcoma management and outcomes: 20-year single-institution experience. Ann Surg Oncol. 2012;19(8):2707–15.CrossRef Look Hong NJ, Pandalai PK, Hornick JL, Shekar PS, Harmon DC, Chen YL, Butrynski JE, Baldini EH, Raut CP. Cardiac angiosarcoma management and outcomes: 20-year single-institution experience. Ann Surg Oncol. 2012;19(8):2707–15.CrossRef
6.
go back to reference Conyers R, Young S, Thomas DM. Liposarcoma: molecular genetics and therapeutics. Sarcoma. 2011;2011:483154.CrossRef Conyers R, Young S, Thomas DM. Liposarcoma: molecular genetics and therapeutics. Sarcoma. 2011;2011:483154.CrossRef
7.
go back to reference Steger CM. Primary liposarcoma of the heart. Case Rep. 2011, 2011:bcr0320114013. Steger CM. Primary liposarcoma of the heart. Case Rep. 2011, 2011:bcr0320114013.
8.
go back to reference Ghadimi MP, Al-Zaid T, Madewell J, Peng T, Colombo C, Hoffman A, Creighton CJ, Zhang Y, Zhang A, Lazar AJ, et al. Diagnosis, management, and outcome of patients with dedifferentiated liposarcoma systemic metastasis. Ann Surg Oncol. 2011;18(13):3762–70.CrossRef Ghadimi MP, Al-Zaid T, Madewell J, Peng T, Colombo C, Hoffman A, Creighton CJ, Zhang Y, Zhang A, Lazar AJ, et al. Diagnosis, management, and outcome of patients with dedifferentiated liposarcoma systemic metastasis. Ann Surg Oncol. 2011;18(13):3762–70.CrossRef
9.
go back to reference Travis WD, Brambilla E, Burke AP, Marx A, Nicholson AG. Introduction to the 2015 World Health Organization classification of tumors of the lung, pleura, thymus, and heart. J Thora Oncol: Off Publ Int Assoc Study Lung Cancer. 2015;10(9):1240–2.CrossRef Travis WD, Brambilla E, Burke AP, Marx A, Nicholson AG. Introduction to the 2015 World Health Organization classification of tumors of the lung, pleura, thymus, and heart. J Thora Oncol: Off Publ Int Assoc Study Lung Cancer. 2015;10(9):1240–2.CrossRef
10.
go back to reference Simpson L, Kumar SK, Okuno SH, Schaff HV, Porrata LF, Buckner JC, Moynihan TJ. Malignant primary cardiac tumors: review of a single institution experience. Cancer. 2008;112(11):2440–6.CrossRef Simpson L, Kumar SK, Okuno SH, Schaff HV, Porrata LF, Buckner JC, Moynihan TJ. Malignant primary cardiac tumors: review of a single institution experience. Cancer. 2008;112(11):2440–6.CrossRef
11.
Metadata
Title
A potential misdiagnosis in the COVID-19 pandemic era: a case report of superimposed thrombosis or tumor recurrence
Authors
Arezou Zoroufian
Reza Mohseni-Badalabadi
Mehrdad Mahalleh
Seyyed Mojtaba Ghorashi
Sharam Momtahen
Negar Omidi
Publication date
01-12-2021
Publisher
BioMed Central
Published in
Journal of Cardiothoracic Surgery / Issue 1/2021
Electronic ISSN: 1749-8090
DOI
https://doi.org/10.1186/s13019-021-01697-3

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