Top

Published in:

Open Access 16-10-2023 | Transcatheter Aortic Valve Implantation | Original Article

Clinical impact of non-lying time on hospital-associated functional decline in older patients undergoing transcatheter aortic valve implantation

Authors: Yuji Kono, Masahiko Mukaino, Yushi Ozawa, Koji Mizutani, Yuki Senju, Takayuki Ogasawara, Masumi Yamaguchi, Takashi Muramatsu, Hideo Izawa, Yohei Otaka

Published in: Heart and Vessels | Issue 3/2024

Abstract

The purposes of the present study were: (1) to investigate the relationship between hospital-associated functional decline (HAFD) and non-lying time and (2) to clarify the optimal cut-off value for non-lying time associated with HAFD in older patients undergoing transcatheter aortic valve implantation (TAVI). From January 2021 to December 2022, patients admitted to a university hospital who underwent trans-femoral TAVI were consecutively recruited. We measured short physical performance battery (SPPB) pre and post-TAVI, and non-lying time from post-operative days 3–5. HAFD was defined as at least 1 point decrease in SPPB during pre and post-TAVI. Among 75 patients (47 female, mean age of 84.5 years) enrolled, 14 patients were classified as having HAFD. Non-lying time was significantly shorter in the HAFD group than in the non-HAFD group (371 min vs. 539 min, P < 0.001). Receiver-operating characteristic analysis determined an optimal cut-off value of 477 min for differentiating the patients more likely to experience HAFD (sensitivity, 75%; specificity, 92%; area under the curve, 0.798). The non-lying time could be one of the associated factors of HAFD in older patients with TAVI. Non-lying time of about 480 min (8 h) during hospitalization may be an initial target for preventing HAFD.

Mahmassani ZS, Reidy PT, McKenzie AI, Stubben C, Howard MT, Drummond MJ (2019) Age-dependent skeletal muscle transcriptome response to bed rest-induced atrophy. J Appl Physiol 126:894–902CrossRefPubMedPubMedCentral

Hirsch CH, Sommers L, Olsen A, Mullen L, Winograd CH (1990) The natural history of functional morbidity in hospitalized older patients. J Am Geriatr Soc 38:1296–1303CrossRefPubMed

Nelson AJ, Montarello NJ, Cosgrove CS, Roberts-Thomson RL, Delacroix S, Chokka RG, Montarello JK, Worthley SG (2018) Transcatheter aortic valve implantation: a new standard of care. Med J Aust 209:136–141CrossRefPubMed

Otto CM, Nishimura RA, Bonow RO, Carabello BA, Erwin JP 3rd, Gentile F, Jneid H, Krieger EV, Mack M, McLeod C, O’Gara PT, Rigolin VH, Sundt TM 3rd, Thompson A, Toly C (2021) 2020 ACC/AHA Guideline for the management of patients with valvular heart disease: executive summary: a report of the American college of cardiology/American heart association joint committee on clinical practice guidelines. Circulation 143:e35–e71PubMed

Saitoh M, Saji M, Kozono-Ikeya A, Arimitsu T, Sakuyama A, Ueki H, Nagayama M, Isobe M (2020) Hospital-acquired functional decline and clinical outcomes in older patients undergoing transcatheter aortic valve implantation. Circ J 84:1083–1089CrossRefPubMed

Ashikaga K, Doi S, Yoneyama K, Watanabe M, Suzuki N, Kuwata S, Kaihara T, Koga M, Okuyama K, Kamijima R, Tanabe Y, Takeichi N, Watanabe S, Izumo M, Kida K, Akashi YJ (2021) Impact of perioperative change in physical function on midterm outcomes after transcatheter aortic valve implantation. Heart Vessels 36:1072–1079CrossRefPubMed

Agmon M, Zisberg A, Gil E, Rand D, Yaish NG, Azriel M (2017) Association between 900 steps a day and functional decline in older hospitalized patients. JAMA Intern Med 177:272–274CrossRefPubMed

Kato M, Mori Y, Watanabe D, Onoda H, Fujiyama K, Toda M, Kito K (2021) Relationship between average daily rehabilitation time and decline in instrumental activity of daily living among older patients with heart failure: a preliminary analysis of a multicenter cohort study. Suruga-Care PLoS One 16:e0254128CrossRefPubMed

Pedersen MM, Bodilsen AC, Petersen J, Beyer N, Andersen O, Lawson-Smith L, Kehlet H, Bandholm T (2013) Twenty-four-hour mobility during acute hospitalization in older medical patients. J Gerontol A Biol Sci Med Sci 68:331–337CrossRefPubMed

10.

Satake S, Shimada H, Yamada M, Kim H, Yoshida H, Gondo Y, Matsubayashi K, Matsushita E, Kuzuya M, Kozaki K, Sugimoto K, Senda K, Sakuma M, Endo N, Arai H (2017) Prevalence of frailty among community-dwellers and outpatients in Japan as defined by the Japanese version of the cardiovascular Health Study criteria. Geriatr Gerontol Int 17:2629–2634CrossRefPubMed

11.

Hamada T, Kubo T, Kawai K, Nakaoka Y, Yabe T, Furuno T, Yamada E, Kitaoka H, Kochi YOSACOI Study (2022) Clinical characteristics and frailty status in heart failure with preserved vs. reduced ejection fraction. ESC Heart Fail 9:1853–1863CrossRefPubMedPubMedCentral

12.

Guralnik JM, Simonsick EM, Ferrucci L, Glynn RJ, Berkman LF, Blazer DG, Scherr PA, Wallace RB (1994) A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol 49:M85–M94CrossRefPubMed

13.

Rauen K, Schaffrath J, Pradhan C, Schniepp R, Jahn K (2018) Accelerometric trunk sensors to detect changes of body positions in immobile patients. Sensors 18:3272ADSCrossRefPubMedPubMedCentral

14.

Fortune E, Lugade VA, Kaufman KR (2014) Posture and movement classification: the comparison of tri-axial accelerometer numbers and anatomical placement. J Biomech Eng 136:051003CrossRefPubMed

15.

Ogasawara T, Mukaino M, Matsuura H, Aoshima Y, Suzuki T, Togo H, Nakashima H, Saitoh E, Yamaguchi M, Otaka Y, Tsukada S (2023) Ensemble averaging for categorical variables: validation study of imputing lost data in 24-h recorded postures of inpatients. Front Physiol 14:1094946CrossRefPubMedPubMedCentral

16.

Puthoff ML (2008) Outcome measures in cardiopulmonary physical therapy: short physical performance battery. Cardiopulm Phys Ther J 19:17–22CrossRefPubMedPubMedCentral

17.

Rolland Y, Lauwers-Cances V, Cesari M, Vellas B, Pahor M, Grandjean H (2006) Physical performance measures as predictors of mortality in a cohort of community-dwelling older French women. Eur J Epidemiol 21:113–122CrossRefPubMed

18.

Puthucheary ZA, Rawal J, McPhail M, Connolly B, Ratnayake G, Chan P, Hopkinson NS, Phadke R, Dew T, Sidhu PS, Velloso C, Seymour J, Agley CC, Selby A, Limb M, Edwards LM, Smith K, Rowlerson A, Rennie MJ, Moxham J, Harridge SD, Hart N, Montgomery HE (2013) Acute skeletal muscle wasting in critical illness. JAMA 310:1591–1600CrossRefPubMed

19.

Schweickert WD, Pohlman MC, Pohlman AS, Nigos C, Pawlik AJ, Esbrook CL, Spears L, Miller M, Franczyk M, Deprizio D, Schmidt GA, Bowman A, Barr R, McCallister KE, Hall JB, Kress JP (2009) Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. Lancet 373:1874–1882CrossRefPubMedPubMedCentral

20.

Portney LG, Watkins MP (2001) Validity of measurements, Chapter 6. Foundations of clinical research applications to practice, 2nd edn. Prentice-Hall Inc. pp 92–101

21.

Mizutani K, Hara M, Iwata S, Murakami T, Shibata T, Yoshiyama M, Naganuma T, Yamanaka F, Higashimori A, Tada N, Takagi K, Araki M, Ueno H, Tabata M, Shirai S, Watanabe Y, Yamamoto M, Hayashida K (2017) Elevation of B-type natriuretic peptide at discharge is associated with 2-year mortality after transcatheter aortic valve replacement in patients with severe aortic stenosis: insights from a multicenter prospective OCEAN-TAVI (Optimized transcatheter valvular intervention-transcatheter aortic valve implantation) registry. J Am Heart Assoc 6:e006112CrossRefPubMedPubMedCentral

22.

Shibata K, Yamamoto M, Kano S, Koyama Y, Shimura T, Kagase A, Yamada S, Kobayashi T, Tada N, Naganuma T, Araki M, Yamanaka F, Shirai S, Mizutani K, Tabata M, Ueno H, Takagi K, Higashimori A, Watanabe Y, Otsuka T, Hayashida K, on the behalf of OCEAN-TAVI investigators (2018) Importance of geriatric nutritional risk index assessment in patients undergoing transcatheter aortic valve replacement. Am Heart J 202:68–75CrossRefPubMed

23.

Kano S, Yamamoto M, Shimura T, Kagase A, Tsuzuki M, Kodama A, Koyama Y, Kobayashi T, Shibata K, Tada N, Naganuma T, Araki M, Yamanaka F, Shirai S, Mizutani K, Tabata M, Ueno H, Takagi K, Higashimori A, Otsuka T, Watanabe Y, Hayashida K (2017) Gait speed can predict advanced clinical outcomes in patients who undergo transcatheter aortic valve replacement: insights from a Japanese multicenter registry. Circ Cardiovasc Interv 10:e005088CrossRefPubMed

Title: Clinical impact of non-lying time on hospital-associated functional decline in older patients undergoing transcatheter aortic valve implantation
Authors: Yuji Kono
Masahiko Mukaino
Yushi Ozawa
Koji Mizutani
Yuki Senju
Takayuki Ogasawara
Masumi Yamaguchi
Takashi Muramatsu
Hideo Izawa
Yohei Otaka
Publication date: 16-10-2023
Publisher: Springer Japan
Keyword: Transcatheter Aortic Valve Implantation
Published in: Heart and Vessels / Issue 3/2024
Print ISSN: 0910-8327
Electronic ISSN: 1615-2573
DOI: https://doi.org/10.1007/s00380-023-02326-w

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Clinical impact of non-lying time on hospital-associated functional decline in older patients undergoing transcatheter aortic valve implantation

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 3/2024

Treatment with catheter ablation for patients with arrhythmia-induced cardiomyopathy caused by atrial fibrillation promises a good prognosis

Mid-term outcomes of surgical aortic valve replacement using a mosaic porcine bioprosthesis with concomitant mitral valve repair

Presystolic wave as a predictor of interatrial block in patients with supraventricular tachycardia

Investigation of the predictive value of a novel algorithm based on coronary CT angiography regarding fractional flow reserve and revascularization in patients with stable coronary artery disease

Can arterial shape change with IABP play a role in comparing FlowTrac/EV 1000 vs. pulmonary cardiac output?

Soluble ST2, BCN-Bio-HF calculator and MAGGIC-HF score in long-term risk prediction after an urgent visit for heart failure